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Protein

Palmitoyltransferase

Gene

BcDNA:AT31918

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Palmitoyl-CoA + [protein]-L-cysteine = [protein]-S-palmitoyl-L-cysteine + CoA.UniRule annotation

GO - Molecular functioni

  • protein-cysteine S-palmitoyltransferase activity Source: FlyBase

GO - Biological processi

  • protein palmitoylation Source: FlyBase

Keywordsi

Molecular functionAcyltransferaseUniRule annotationImported, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
PalmitoyltransferaseUniRule annotation (EC:2.3.1.225UniRule annotation)
Gene namesi
Name:BcDNA:AT31918Imported
Synonyms:anon-WO0118547.38Imported, Dmel\CG13029Imported
ORF Names:CG13029Imported, Dmel_CG13029Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 3L

Organism-specific databases

FlyBaseiFBgn0036670. CG13029.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei22 – 44HelicalUniRule annotationAdd BLAST23
Transmembranei56 – 73HelicalUniRule annotationAdd BLAST18
Transmembranei149 – 173HelicalUniRule annotationAdd BLAST25
Transmembranei201 – 226HelicalUniRule annotationAdd BLAST26

GO - Cellular componenti

  • endoplasmic reticulum Source: FlyBase
  • integral component of membrane Source: UniProtKB-KW

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiQ8IQN9.
PRIDEiQ8IQN9.

Expressioni

Gene expression databases

BgeeiFBgn0036670.
ExpressionAtlasiQ8IQN9. differential.
GenevisibleiQ8IQN9. DM.

Interactioni

Protein-protein interaction databases

STRINGi7227.FBpp0075095.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini104 – 236zf-DHHCInterPro annotationAdd BLAST133

Domaini

The DHHC domain is required for palmitoyltransferase activity.UniRule annotation

Sequence similaritiesi

Belongs to the DHHC palmitoyltransferase family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

eggNOGiKOG1311. Eukaryota.
COG5273. LUCA.
GeneTreeiENSGT00850000132405.
InParanoidiQ8IQN9.
OMAiGHNNYRY.
OrthoDBiEOG091G0RWR.
PhylomeDBiQ8IQN9.

Family and domain databases

InterProiView protein in InterPro
IPR001594. Palmitoyltrfase_DHHC.
PfamiView protein in Pfam
PF01529. zf-DHHC. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8IQN9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MCFMMIGCKY IANANPKRFA KIVHPSAVGF VLVGTVLFFS VEMFYMLPRI
60 70 80 90 100
YDTDGLFFKI AWLMALFIVY NLLGNMLACH RNSSAVTSLP KDRQIPCPEE
110 120 130 140 150
KHLWHFCDHC QMLVPPRSWH CKVCECCILR RDHHCIFTAT CVGHTNYRYF
160 170 180 190 200
FWFTVYMHIG SLLSLATHVN LLIIDEQIRR QYVVLHFSRF FLFLKPMSCE
210 220 230 240 250
LIALNISFII NIYACILSLI MLGYQIPALY LNTTFYTPKD YRYNQGLLGN
260 270 280
FMAFMGKRGL WTFISPSIRS PLPHDGTKWQ TKQAPTTF
Length:288
Mass (Da):33,598
Last modified:March 1, 2003 - v1
Checksum:i7FCD738BE68B6B7B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014296 Genomic DNA. Translation: AAN11745.1.
RefSeqiNP_648928.1. NM_140671.2.
UniGeneiDm.29701.

Genome annotation databases

EnsemblMetazoaiFBtr0075336; FBpp0075095; FBgn0036670.
GeneIDi39886.
UCSCiCG13029-RC. d. melanogaster.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014296 Genomic DNA. Translation: AAN11745.1.
RefSeqiNP_648928.1. NM_140671.2.
UniGeneiDm.29701.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7227.FBpp0075095.

Proteomic databases

PaxDbiQ8IQN9.
PRIDEiQ8IQN9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0075336; FBpp0075095; FBgn0036670.
GeneIDi39886.
UCSCiCG13029-RC. d. melanogaster.

Organism-specific databases

FlyBaseiFBgn0036670. CG13029.

Phylogenomic databases

eggNOGiKOG1311. Eukaryota.
COG5273. LUCA.
GeneTreeiENSGT00850000132405.
InParanoidiQ8IQN9.
OMAiGHNNYRY.
OrthoDBiEOG091G0RWR.
PhylomeDBiQ8IQN9.

Miscellaneous databases

GenomeRNAii39886.

Gene expression databases

BgeeiFBgn0036670.
ExpressionAtlasiQ8IQN9. differential.
GenevisibleiQ8IQN9. DM.

Family and domain databases

InterProiView protein in InterPro
IPR001594. Palmitoyltrfase_DHHC.
PfamiView protein in Pfam
PF01529. zf-DHHC. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ8IQN9_DROME
AccessioniPrimary (citable) accession number: Q8IQN9
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: April 12, 2017
This is version 114 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.