Q8IQN5 (Q8IQN5_DROME) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Notum, isoform B EMBL AAN11756.2

Gene names

Name:	Notum EMBL AAN11756.2
ORF Names:	Dmel_CG13076 EMBL AAN11756.2

Organism

Drosophila melanogaster (Fruit fly)

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	693 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	GPI anchor release Inferred from mutant phenotype. Source: FlyBase Wnt receptor signaling pathway Inferred from mutant phenotype. Source: FlyBase negative regulation of Wnt receptor signaling pathway Non-traceable author statement. Source: FlyBase proteoglycan metabolic process Non-traceable author statement. Source: FlyBase regulation of compound eye pigmentation Inferred from mutant phenotype. Source: FlyBase wing disc dorsal/ventral pattern formation Inferred from genetic interaction. Source: FlyBase
Cellular component	extracellular space Inferred from direct assay. Source: FlyBase
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8IQN5 [UniParc]. Last modified July 5, 2004. Version 2. Checksum: 50FAA91C7A800DAA	FASTA	693	79,491
	10 20 30 40 50 60 MAVEQIDKMA AKAGEATNKW IKPQQPLLTL LLLLATFSQL PAVCSSSILD AASLQEKDPL 70 80 90 100 110 120 RDTSMNMIQR NYMVMHSASG SGDHSRSLKR ANLANTSITC NDGSHAGFYL RKHPSSKKWI 130 140 150 160 170 180 VLLEGGWHCF DVRSCRSRWM RLRHLMTSSQ WPETRDGECD IKINEITMIS NHFILHFPVG 190 200 210 220 230 240 GILSPHPEEN PYWHNANHVL IPYCSSDSWS GTRTEPDTSD RENSWRFMGA LILRQVIAEL 250 260 270 280 290 300 IPVGLGRVPG GELMLVGSSA GGMGVMLNLD RIRDFLVNEK KLQITVRGVS DSGWFLDREP 310 320 330 340 350 360 YTPAAVASNE AVRQGWKLWQ GLLPEECTKS YPTEPWRCYY GYRLYPTLKT PLFVFQWLFD 370 380 390 400 410 420 EAQMRVDNVG APVTPQQWNY IHEMGGALRS SLDNVSAVFA PSCIGHGVLF KRDWVNIKID 430 440 450 460 470 480 DISLPSALRC WEHSTRSRRH DKLKRSTEPS TAVSHPEHAN NQRHQRHRQR LQRQKHNNVA 490 500 510 520 530 540 QSGGQQRKHN HLSKEEREER KRLRQEQRQR RKQRRRQQQQ KKANGGQEHR NKKDNSPKSS 550 560 570 580 590 600 NGNDQRKQRR RQQLTAEERQ EQRKRRRKAQ QQQMKMQREQ PAAGVFLEAS APQKTRSSNN 610 620 630 640 650 660 ASAGTKSKKR HRVPRVPEKC GLRLLERCSW PQCNHSCPTL TNPMTGEEMR FLELLTAFGL 670 680 690 DIEAVAAALG VDMHTLNNME RTELVNMLTQ QAN

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review." Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E. Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed: 12537572] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: Berkeley.
[2]	"The genome sequence of Drosophila melanogaster." Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.H., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Gabor G.L., Abril J.F., Agbayani A., An H.J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., WoodageT, Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C. Science 287:2185-2195(2000) [PubMed: 10731132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE014296 Genomic DNA. Translation: AAN11756.2.
RefSeq	NP_730095.2. NM_168642.2.
UniGene	Dm.12824.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q8IQN5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblMetazoa	FBtr0075436; FBpp0075194; FBgn0044028.
GeneID	39751.
KEGG	dme:Dmel_CG13076.
NMPDR	fig|7227.3.peg.10037.
UCSC	CG13076-RB. d. melanogaster.
Organism-specific databases
CTD	147111.
FlyBase	FBgn0044028. Notum.
Phylogenomic databases
eggNOG	inNOG06201.
GeneTree	EMGT00050000006187.
InParanoid	Q8IQN5.
OMA	WFLDREP.
OrthoDB	EOG4X69QM.
PhylomeDB	Q8IQN5.
Gene expression databases
ArrayExpress	Q8IQN5.
Bgee	Q8IQN5.
Family and domain databases
ProtoNet	Search...
Other
NextBio	815196.

Entry information

Entry name

Q8IQN5_DROME

Accession

Primary (citable) accession number: Q8IQN5

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2003
Last sequence update:	July 5, 2004
Last modified:	January 25, 2012
This is version 60 of the entry and version 2 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)