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Q8IQF8 (Q8IQF8_DROME) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 80. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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to top of pageNames·Attributes·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesSubmitted name:
AT18092p EMBL AAR96205.1
Submitted name:
CG6084, isoform B EMBL AAN11878.1
EC=1.1.1.21 EMBL AAN11878.1
Gene names
ORF Names:CG6084 FlyBase FBgn0036182 EMBL AAR96205.1 FlyBase FBgn0086254, Dmel_CG6084 EMBL AAN11878.1
OrganismDrosophila melanogaster (Fruit fly)
Taxonomic identifier7227 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length350 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

Ontologies

Keywords
   Molecular functionOxidoreductase EMBL AAN11878.1
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Molecular functionalditol:NADP+ 1-oxidoreductase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site841Proton donor By similarity PIRSR PIRSR000097-1

Sequences

Sequence LengthMass (Da)Tools
Q8IQF8 [UniParc].

Last modified March 1, 2003. Version 1.
Checksum: DC24108DE598F031

FASTA35040,110
        10         20         30         40         50         60 
MNTLMKIQLV RPVFRITLRN YGKPERFMWC QKEYARAPKV VCLDGNEIPV IGLGTFNSPK 

        70         80         90        100        110        120 
GQVTEAVKVA IDAGYRHIDC AYVYQNEDEV GDGVEAKIKE GVVKREDLFI TSKLWNTFHR 

       130        140        150        160        170        180 
PDLVKSALEN TLSSLKLKYL DLYLIHWPMG YKEGCDLFPT DKDGKTLYSP VDYVDTWKAM 

       190        200        210        220        230        240 
EKLVEEGLVK SIGVSNFNRR QIERVLEVAT IPPVTNQIEC HPYLTQKKLI DFCKSKDITI 

       250        260        270        280        290        300 
TAYSPLGSPN RPWAKAGDPV ILEEAKIKEI AAKKKKTPGQ ILIRYQVQRA NIVIPKSVTK 

       310        320        330        340        350 
DRIESNFQVF DFELTPEEIE IIESFECNGR LVPLLKDAGT HKYYPFHDEY

« Hide

References

« Hide 'large scale' references
[1]"The genome sequence of Drosophila melanogaster."
Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. expand/collapse author list , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.H., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Gabor G.L., Abril J.F., Agbayani A., An H.J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., WoodageT, Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.
Science 287:2185-2195(2000) [PubMed: 10731132] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Berkeley.
[2]"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review."
Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. expand/collapse author list , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E.
Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed: 12537572] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: Berkeley.
[3]Stapleton M., Carlson J., Chavez C., Frise E., George R., Pacleb J., Park S., Wan K., Yu C., Rubin G.M., Celniker S.
Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE014296 Genomic DNA. Translation: AAN11878.1.
BT011413 mRNA. Translation: AAR96205.1.
RefSeqNP_729726.1. NM_168467.1.
UniGeneDm.6959.

3D structure databases

HSSPHSSP built from PDB template 1AH0 based on UniProtKB P80276.
ProteinModelPortalQ8IQF8.
SMRQ8IQF8. Positions 47-350.
ModBaseSearch...

Protein-protein interaction databases

IntActQ8IQF8. 1 interaction.
MINTMINT-895352.
STRINGQ8IQF8.

Proteomic databases

PRIDEQ8IQF8.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaFBtr0076138; FBpp0075869; FBgn0086254.
GeneID39304.
KEGGdme:Dmel_CG6084.
NMPDRfig|7227.3.peg.9391.
UCSCCG6084-RB. d. melanogaster.

Organism-specific databases

FlyBaseFBgn0086254. CG6084.

Phylogenomic databases

eggNOGinNOG04180.
GeneTreeEMGT00050000002490.
InParanoidQ8IQF8.
OrthoDBEOG4GHX52.
PhylomeDBQ8IQF8.

Gene expression databases

ArrayExpressQ8IQF8.
BgeeQ8IQF8.

Family and domain databases

InterProIPR001395. Aldo/ket_red.
IPR018170. Aldo/ket_reductase_CS.
IPR020471. Aldo/keto_reductase_subgr.
IPR023210. NADP_OxRdtase_dom.
[Graphical view]
Gene3DG3DSA:3.20.20.100. Aldo/ket_red. 1 hit.
KOK00011.
PANTHERPTHR11732. Aldo/ket_red. 1 hit.
PfamPF00248. Aldo_ket_red. 1 hit.
[Graphical view]
PIRSFPIRSF000097. AKR. 1 hit.
PRINTSPR00069. ALDKETRDTASE.
SUPFAMSSF51430. Aldo/ket_red. 1 hit.
PROSITEPS00798. ALDOKETO_REDUCTASE_1. 1 hit.
PS00062. ALDOKETO_REDUCTASE_2. 1 hit.
PS00063. ALDOKETO_REDUCTASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio812958.

Entry information

Entry nameQ8IQF8_DROME
AccessionPrimary (citable) accession number: Q8IQF8
Entry history
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: January 25, 2012
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info