Q8IQ79 (Q8IQ79_DROME) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Sphinx1 EMBL AAN12063.2
EC=3.4.21.- EMBL AAN12063.2

Gene names

Name:	sphinx1 EMBL AAN12063.2 FlyBase FBgn0052383
ORF Names:	Dmel_CG32383 EMBL AAN12063.2

Organism

Drosophila melanogaster (Fruit fly)

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	253 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the peptidase S1 family. RuleBase RU000360

Ontologies

Keywords
Molecular function	Hydrolase EMBL AAN12063.2
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	defense response to Gram-negative bacterium Inferred from mutant phenotype. Source: FlyBase defense response to Gram-positive bacterium Inferred from mutant phenotype. Source: FlyBase defense response to fungus Inferred from mutant phenotype. Source: FlyBase innate immune response Inferred from mutant phenotype. Source: FlyBase positive regulation of Toll signaling pathway Inferred from mutant phenotype. Source: FlyBase proteolysis Inferred from electronic annotation. Source: InterPro
Molecular function	serine-type endopeptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8IQ79 [UniParc]. Last modified November 30, 2010. Version 2. Checksum: 0782F37C983DD793	FASTA	253	29,067
	10 20 30 40 50 60 MKLVVTLLVL SLTVSVGEKN KLSPRIAGGY RAKTFTIIYL VGIVYFKSQT SSLNYGAGTI 70 80 90 100 110 120 ISNQWILTVK TVLKYSYIEV HLASRRSYRG FDIIRIYKEN FRFHYDNDHV IALVKCPYQK 130 140 150 160 170 180 FDRRMDRVRV PAYDTRFERY VGNMTMVCGY GTEKRHAKLP EWMRCIEVEV MNNTECAKYY 190 200 210 220 230 240 TPLKWYEMCT SGEGFKGVCE GDIGGAVVTM GPNPTFIGII WLMPENCSIG YPSVHIRVSD 250 HIKWIKRVSG VGF

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review." Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E. Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed: 12537572] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: Berkeley.
[2]	"The genome sequence of Drosophila melanogaster." Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.H., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Gabor G.L., Abril J.F., Agbayani A., An H.J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., WoodageT, Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C. Science 287:2185-2195(2000) [PubMed: 10731132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE014296 Genomic DNA. Translation: AAN12063.2.
RefSeq	NP_729255.2. NM_168214.2.
UniGene	Dm.27832.
3D structure databases
ProteinModelPortal	Q8IQ79.
SMR	Q8IQ79. Positions 26-253.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblMetazoa	FBtr0300363; FBpp0289592; FBgn0052383.
GeneID	318005.
KEGG	dme:Dmel_CG32383.
UCSC	CG32383-RB. d. melanogaster.
Organism-specific databases
CTD	318005.
FlyBase	FBgn0052383. sphinx1.
Phylogenomic databases
GeneTree	EMGT00050000002547.
OrthoDB	EOG40RXXM.
Gene expression databases
Bgee	Q8IQ79.
Family and domain databases
InterPro	IPR009003. Pept_cys/ser_Trypsin-like. IPR001254. Peptidase_S1_S6. [Graphical view]
Pfam	PF00089. Trypsin. 1 hit. [Graphical view]
SMART	SM00020. Tryp_SPc. 1 hit. [Graphical view]
SUPFAM	SSF50494. Pept_Ser_Cys. 1 hit.
PROSITE	PS50240. TRYPSIN_DOM. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q8IQ79_DROME

Accession

Primary (citable) accession number: Q8IQ79

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2003
Last sequence update:	November 30, 2010
Last modified:	January 25, 2012
This is version 74 of the entry and version 2 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)