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Q8IPK4 (GLT25_DROME) Reviewed, UniProtKB/Swiss-Prot

Last modified November 13, 2013. Version 70. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glycosyltransferase 25 family member

EC=2.-.-.-
Gene names
ORF Names:CG31915
OrganismDrosophila melanogaster (Fruit fly) [Reference proteome]
Taxonomic identifier7227 [NCBI]
Taxonomic lineageEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora

Protein attributes

Sequence length612 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Subcellular location

Endoplasmic reticulum lumen Potential.

Sequence similarities

Belongs to the glycosyltransferase 25 family.

Sequence caution

The sequence ABY21735.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
   Cellular componentEndoplasmic reticulum
   DomainSignal
   Molecular functionGlycosyltransferase
Transferase
   PTMGlycoprotein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processlipopolysaccharide biosynthetic process

Inferred from electronic annotation. Source: InterPro

   Cellular_componentendoplasmic reticulum lumen

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functiontransferase activity, transferring glycosyl groups

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2020 Potential
Chain21 – 612592Glycosyltransferase 25 family member
PRO_0000309549

Regions

Motif609 – 6124Prevents secretion from ER Potential

Amino acid modifications

Glycosylation1061N-linked (GlcNAc...) Potential
Glycosylation2271N-linked (GlcNAc...) Potential
Glycosylation2631N-linked (GlcNAc...) Potential
Glycosylation5241N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
Q8IPK4 [UniParc].

Last modified March 1, 2003. Version 1.
Checksum: 5719BCE07C7698B6

FASTA61271,149
        10         20         30         40         50         60 
MNKQVIFGLL LACILVCISG QDEEDYQESP TVLIALLVRN KAHILPMFLS YLEQQDYPKE 

        70         80         90        100        110        120 
RIAIWLRCDH SNDDSIELLR QWLDNSGDLY HSVSYEFKPE EQSFVNGTSP YEWPASRFKH 

       130        140        150        160        170        180 
LIALKEEAFQ YGRDIWADYV FFLDADVLLT SKDSLKVLTR LQLPIVAPML ISESLYSNFW 

       190        200        210        220        230        240 
CGMTEDYYYR RTDEYKEIYH VKKQGSFPVP MVHTAVLVNM NHRAVRNLTF DRNKLVELQK 

       250        260        270        280        290        300 
SRQQEPLYDG PADDIIVFAI SANSSGIPLH ICNDITFGYI LQPLEPGDTL DHDVQQLVNL 

       310        320        330        340        350        360 
KSIMVNELGA VPPLLDYYKH LEKKPEKSKL SLDRIFMINL KRRPERREKM ERLFDEIGIE 

       370        380        390        400        410        420 
AEHFPAVDGK ELSTERLLEM GVRFLPGYED PYHHRAMTMG EIGCFLSHYN IWVMMVRKQL 

       430        440        450        460        470        480 
KEVLILEDDI RFEPYFRQNA VRILNQARNA AQYDLIYFGR KRLKEESEPA VENADNLVHA 

       490        500        510        520        530        540 
GYSYWTLGYV ISLQGALKLL AAKPLDKLIP VDEFLPLMFD RHPNKTWTEA FPKRNLVAFS 

       550        560        570        580        590        600 
ASPLLLYPIY YTGESGYISD TEDSQQISVE TSEEGEARLK SDREQVFDHE QEFKLNPELK 

       610 
LGESLSKSHQ EL 

« Hide

References

« Hide 'large scale' references
[1]"The genome sequence of Drosophila melanogaster."
Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. expand/collapse author list , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.
Science 287:2185-2195(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Berkeley.
[2]"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review."
Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. expand/collapse author list , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E.
Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: Berkeley.
[3]Stapleton M., Carlson J.W., Frise E., Kapadia B., Park S., Wan K.H., Yu C., Celniker S.E.
Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: Berkeley.
Tissue: Embryo.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE014134 Genomic DNA. Translation: AAN10543.1.
BT031322 mRNA. Translation: ABY21735.1. Different initiation.
RefSeqNP_723087.1. NM_164645.2.
UniGeneDm.33617.

3D structure databases

ProteinModelPortalQ8IPK4.
ModBaseSearch...
MobiDBSearch...

Protein family/group databases

CAZyGT25. Glycosyltransferase Family 25.

Proteomic databases

PaxDbQ8IPK4.
PRIDEQ8IPK4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaFBtr0079099; FBpp0078732; FBgn0051915.
GeneID319025.
KEGGdme:Dmel_CG31915.
UCSCCG31915-RA. d. melanogaster.

Organism-specific databases

FlyBaseFBgn0051915. CG31915.

Phylogenomic databases

eggNOGNOG293154.
GeneTreeENSGT00550000074427.
InParanoidQ8IPK4.
KOK11703.
OMAPEESKMQ.
OrthoDBEOG7060RC.
PhylomeDBQ8IPK4.

Gene expression databases

BgeeQ8IPK4.

Family and domain databases

InterProIPR002654. Glyco_trans_25.
[Graphical view]
PfamPF01755. Glyco_transf_25. 1 hit.
[Graphical view]
PROSITEPS00014. ER_TARGET. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

GenomeRNAi319025.
NextBio847004.

Entry information

Entry nameGLT25_DROME
AccessionPrimary (citable) accession number: Q8IPK4
Secondary accession number(s): A9UNF8
Entry history
Integrated into UniProtKB/Swiss-Prot: November 13, 2007
Last sequence update: March 1, 2003
Last modified: November 13, 2013
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

Relevant documents

SIMILARITY comments

Index of protein domains and families

Drosophila

Drosophila: entries, gene names and cross-references to FlyBase