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Q8IPK4

- GLT25_DROME

UniProt

Q8IPK4 - GLT25_DROME

Protein

Glycosyltransferase 25 family member

Gene

CG31915

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 73 (01 Oct 2014)
      Sequence version 1 (01 Mar 2003)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. transferase activity, transferring glycosyl groups Source: UniProtKB-KW

    GO - Biological processi

    1. lipopolysaccharide biosynthetic process Source: InterPro

    Keywords - Molecular functioni

    Glycosyltransferase, Transferase

    Protein family/group databases

    CAZyiGT25. Glycosyltransferase Family 25.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glycosyltransferase 25 family member (EC:2.-.-.-)
    Gene namesi
    ORF Names:CG31915
    OrganismiDrosophila melanogaster (Fruit fly)
    Taxonomic identifieri7227 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
    ProteomesiUP000000803: Chromosome 2L

    Organism-specific databases

    FlyBaseiFBgn0051915. CG31915.

    Subcellular locationi

    Endoplasmic reticulum lumen PROSITE-ProRule annotation

    GO - Cellular componenti

    1. endoplasmic reticulum lumen Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Endoplasmic reticulum

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 2020Sequence AnalysisAdd
    BLAST
    Chaini21 – 612592Glycosyltransferase 25 family memberPRO_0000309549Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Glycosylationi106 – 1061N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi227 – 2271N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi263 – 2631N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi524 – 5241N-linked (GlcNAc...)Sequence Analysis

    Keywords - PTMi

    Glycoprotein

    Proteomic databases

    PaxDbiQ8IPK4.
    PRIDEiQ8IPK4.

    Expressioni

    Gene expression databases

    BgeeiQ8IPK4.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8IPK4.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Motif

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Motifi609 – 6124Prevents secretion from ERPROSITE-ProRule annotation

    Sequence similaritiesi

    Belongs to the glycosyltransferase 25 family.Curated

    Keywords - Domaini

    Signal

    Phylogenomic databases

    eggNOGiNOG293154.
    GeneTreeiENSGT00550000074427.
    InParanoidiQ8IPK4.
    KOiK11703.
    OMAiPEESKMQ.
    OrthoDBiEOG7060RC.
    PhylomeDBiQ8IPK4.

    Family and domain databases

    InterProiIPR002654. Glyco_trans_25.
    IPR029044. Nucleotide-diphossugar_trans.
    [Graphical view]
    PfamiPF01755. Glyco_transf_25. 1 hit.
    [Graphical view]
    SUPFAMiSSF53448. SSF53448. 1 hit.
    PROSITEiPS00014. ER_TARGET. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q8IPK4-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNKQVIFGLL LACILVCISG QDEEDYQESP TVLIALLVRN KAHILPMFLS    50
    YLEQQDYPKE RIAIWLRCDH SNDDSIELLR QWLDNSGDLY HSVSYEFKPE 100
    EQSFVNGTSP YEWPASRFKH LIALKEEAFQ YGRDIWADYV FFLDADVLLT 150
    SKDSLKVLTR LQLPIVAPML ISESLYSNFW CGMTEDYYYR RTDEYKEIYH 200
    VKKQGSFPVP MVHTAVLVNM NHRAVRNLTF DRNKLVELQK SRQQEPLYDG 250
    PADDIIVFAI SANSSGIPLH ICNDITFGYI LQPLEPGDTL DHDVQQLVNL 300
    KSIMVNELGA VPPLLDYYKH LEKKPEKSKL SLDRIFMINL KRRPERREKM 350
    ERLFDEIGIE AEHFPAVDGK ELSTERLLEM GVRFLPGYED PYHHRAMTMG 400
    EIGCFLSHYN IWVMMVRKQL KEVLILEDDI RFEPYFRQNA VRILNQARNA 450
    AQYDLIYFGR KRLKEESEPA VENADNLVHA GYSYWTLGYV ISLQGALKLL 500
    AAKPLDKLIP VDEFLPLMFD RHPNKTWTEA FPKRNLVAFS ASPLLLYPIY 550
    YTGESGYISD TEDSQQISVE TSEEGEARLK SDREQVFDHE QEFKLNPELK 600
    LGESLSKSHQ EL 612
    Length:612
    Mass (Da):71,149
    Last modified:March 1, 2003 - v1
    Checksum:i5719BCE07C7698B6
    GO

    Sequence cautioni

    The sequence ABY21735.1 differs from that shown. Reason: Erroneous initiation.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE014134 Genomic DNA. Translation: AAN10543.1.
    BT031322 mRNA. Translation: ABY21735.1. Different initiation.
    RefSeqiNP_723087.1. NM_164645.2.
    UniGeneiDm.33617.

    Genome annotation databases

    EnsemblMetazoaiFBtr0079099; FBpp0078732; FBgn0051915.
    GeneIDi319025.
    KEGGidme:Dmel_CG31915.
    UCSCiCG31915-RA. d. melanogaster.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE014134 Genomic DNA. Translation: AAN10543.1 .
    BT031322 mRNA. Translation: ABY21735.1 . Different initiation.
    RefSeqi NP_723087.1. NM_164645.2.
    UniGenei Dm.33617.

    3D structure databases

    ProteinModelPortali Q8IPK4.
    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    CAZyi GT25. Glycosyltransferase Family 25.

    Proteomic databases

    PaxDbi Q8IPK4.
    PRIDEi Q8IPK4.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblMetazoai FBtr0079099 ; FBpp0078732 ; FBgn0051915 .
    GeneIDi 319025.
    KEGGi dme:Dmel_CG31915.
    UCSCi CG31915-RA. d. melanogaster.

    Organism-specific databases

    FlyBasei FBgn0051915. CG31915.

    Phylogenomic databases

    eggNOGi NOG293154.
    GeneTreei ENSGT00550000074427.
    InParanoidi Q8IPK4.
    KOi K11703.
    OMAi PEESKMQ.
    OrthoDBi EOG7060RC.
    PhylomeDBi Q8IPK4.

    Miscellaneous databases

    GenomeRNAii 319025.
    NextBioi 847004.

    Gene expression databases

    Bgeei Q8IPK4.

    Family and domain databases

    InterProi IPR002654. Glyco_trans_25.
    IPR029044. Nucleotide-diphossugar_trans.
    [Graphical view ]
    Pfami PF01755. Glyco_transf_25. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53448. SSF53448. 1 hit.
    PROSITEi PS00014. ER_TARGET. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The genome sequence of Drosophila melanogaster."
      Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D.
      , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.
      Science 287:2185-2195(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Berkeley.
    2. Cited for: GENOME REANNOTATION.
      Strain: Berkeley.
    3. Stapleton M., Carlson J.W., Frise E., Kapadia B., Park S., Wan K.H., Yu C., Celniker S.E.
      Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: Berkeley.
      Tissue: Embryo.

    Entry informationi

    Entry nameiGLT25_DROME
    AccessioniPrimary (citable) accession number: Q8IPK4
    Secondary accession number(s): A9UNF8
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 13, 2007
    Last sequence update: March 1, 2003
    Last modified: October 1, 2014
    This is version 73 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programDrosophila annotation project

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Drosophila
      Drosophila: entries, gene names and cross-references to FlyBase
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3