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Protein
Submitted name:

Deoxyuridine triphosphatase, isoform B

Gene

dUTPase

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • dUTP diphosphatase activity Source: FlyBase

GO - Biological processi

  • dUTP metabolic process Source: FlyBase

Keywordsi

Molecular functionHydrolaseImported

Enzyme and pathway databases

ReactomeiR-DME-499943. Interconversion of nucleotide di- and triphosphates.

Names & Taxonomyi

Protein namesi
Submitted name:
Deoxyuridine triphosphatase, isoform BImported
Submitted name:
Deoxyuridine triphosphatase, isoform CImported
Submitted name:
Deoxyuridine triphosphatase, isoform DImported (EC:3.6.1.23Imported)
Submitted name:
LD28081pImported
Gene namesi
Name:dUTPaseImported
Synonyms:dUTPase-RBImported
ORF Names:CG4584Imported, Dmel_CG4584Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 2L

Organism-specific databases

FlyBaseiFBgn0250837. dUTPase.

Subcellular locationi

GO - Cellular componenti

  • cytoplasm Source: FlyBase
  • nucleus Source: FlyBase
  • plasma membrane Source: FlyBase

Expressioni

Gene expression databases

BgeeiFBgn0250837.

Interactioni

Protein-protein interaction databases

STRINGi7227.FBpp0079746.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini20 – 144dUTPaseInterPro annotationAdd BLAST125

Phylogenomic databases

eggNOGiKOG3370. Eukaryota.
COG0756. LUCA.
GeneTreeiENSGT00390000018390.
KOiK01520.
OrthoDBiEOG091G14FN.

Family and domain databases

CDDicd07557. trimeric_dUTPase. 1 hit.
InterProiView protein in InterPro
IPR029054. dUTPase-like.
IPR008181. dUTPase_1.
IPR033704. dUTPase_trimeric.
PfamiView protein in Pfam
PF00692. dUTPase. 1 hit.
SUPFAMiSSF51283. SSF51283. 1 hit.
TIGRFAMsiTIGR00576. dut. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8IPB1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKIDTCVLRF AKLTENALEP VRGSAKAAGV DLRSAYDVVV PARGKAIVKT
60 70 80 90 100
DLQVQVPEGS YGRVAPRSGL AVKNFIDVGA GVVDEDYRGN LGVVLFNHSD
110 120 130 140 150
VDFEVKHGDR IAQFICERIF YPQLVMVDKL EDTERGEAGF GSTGVKDLPA
160 170
AKAQNGNGEK AAEPEGAAPA PVAT
Length:174
Mass (Da):18,485
Last modified:March 1, 2003 - v1
Checksum:i3CDC35D97AAEDFE5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014134 Genomic DNA. Translation: AAN10772.1.
BT089034 mRNA. Translation: ACU12380.1.
AE014134 Genomic DNA. Translation: AGB92905.1.
AE014134 Genomic DNA. Translation: AGB92906.1.
RefSeqiNP_001260370.1. NM_001273441.2.
NP_001260371.1. NM_001273442.2.
NP_723647.1. NM_164956.3.
UniGeneiDm.3087.

Genome annotation databases

EnsemblMetazoaiFBtr0080156; FBpp0079745; FBgn0250837.
FBtr0331195; FBpp0303622; FBgn0250837.
FBtr0331196; FBpp0303623; FBgn0250837.
GeneIDi34529.
KEGGidme:Dmel_CG4584.
UCSCiCG4584-RB. d. melanogaster.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014134 Genomic DNA. Translation: AAN10772.1.
BT089034 mRNA. Translation: ACU12380.1.
AE014134 Genomic DNA. Translation: AGB92905.1.
AE014134 Genomic DNA. Translation: AGB92906.1.
RefSeqiNP_001260370.1. NM_001273441.2.
NP_001260371.1. NM_001273442.2.
NP_723647.1. NM_164956.3.
UniGeneiDm.3087.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7227.FBpp0079746.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0080156; FBpp0079745; FBgn0250837.
FBtr0331195; FBpp0303622; FBgn0250837.
FBtr0331196; FBpp0303623; FBgn0250837.
GeneIDi34529.
KEGGidme:Dmel_CG4584.
UCSCiCG4584-RB. d. melanogaster.

Organism-specific databases

CTDi34529.
FlyBaseiFBgn0250837. dUTPase.

Phylogenomic databases

eggNOGiKOG3370. Eukaryota.
COG0756. LUCA.
GeneTreeiENSGT00390000018390.
KOiK01520.
OrthoDBiEOG091G14FN.

Enzyme and pathway databases

ReactomeiR-DME-499943. Interconversion of nucleotide di- and triphosphates.

Miscellaneous databases

GenomeRNAii34529.

Gene expression databases

BgeeiFBgn0250837.

Family and domain databases

CDDicd07557. trimeric_dUTPase. 1 hit.
InterProiView protein in InterPro
IPR029054. dUTPase-like.
IPR008181. dUTPase_1.
IPR033704. dUTPase_trimeric.
PfamiView protein in Pfam
PF00692. dUTPase. 1 hit.
SUPFAMiSSF51283. SSF51283. 1 hit.
TIGRFAMsiTIGR00576. dut. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ8IPB1_DROME
AccessioniPrimary (citable) accession number: Q8IPB1
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: June 7, 2017
This is version 118 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.