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Protein
Submitted name:

DEAD/DEAH box helicase, putative

Gene

PF14_0234

Organism
Plasmodium falciparum (isolate 3D7)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-directed DNA polymeraseImported, HelicaseImported, Hydrolase, Nucleotidyltransferase, Transferase
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
DEAD/DEAH box helicase, putativeImported (EC:3.6.4.13Imported)
Submitted name:
DNA-directed DNA polymerase, putativeImported
Gene namesi
ORF Names:PF14_0234Imported, PF3D7_1425400Imported
OrganismiPlasmodium falciparum (isolate 3D7)Imported
Taxonomic identifieri36329 [NCBI]
Taxonomic lineageiEukaryotaAlveolataApicomplexaAconoidasidaHaemosporidaPlasmodiidaePlasmodiumPlasmodium (Laverania)
Proteomesi
  • UP000001450 Componenti: Chromosome 14

Organism-specific databases

EuPathDBiPlasmoDB:PF3D7_1425400.

Subcellular locationi

GO - Cellular componenti

Structurei

3D structure databases

SMRiQ8ILK9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini77 – 269Helicase ATP-bindingInterPro annotationAdd BLAST193
Domaini632 – 812Helicase C-terminalInterPro annotationAdd BLAST181

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili961 – 981Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

HOGENOMiHOG000281276.
InParanoidiQ8ILK9.
KOiK02349.
OMAiADQSANQ.

Family and domain databases

CDDicd00079. HELICc. 1 hit.
InterProiView protein in InterPro
IPR011545. DEAD/DEAH_box_helicase_dom.
IPR014001. Helicase_ATP-bd.
IPR001650. Helicase_C.
IPR027417. P-loop_NTPase.
PfamiView protein in Pfam
PF00270. DEAD. 1 hit.
PF00271. Helicase_C. 1 hit.
SMARTiView protein in SMART
SM00487. DEXDc. 1 hit.
SM00490. HELICc. 1 hit.
SUPFAMiSSF52540. SSF52540. 4 hits.
PROSITEiView protein in PROSITE
PS51192. HELICASE_ATP_BIND_1. 1 hit.
PS51194. HELICASE_CTER. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8ILK9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNKNWIKNLE NIIDKNKIFE WDEKKNEKLK DVCKNFIKKD YSIHHYVTNP
60 70 80 90 100
IIIDNYKKEK IKELYEWQDE CLRELRKVNW EKGENFICVA PTSGGKTLVT
110 120 130 140 150
ELFIFEEIKN GKKQIFFLFP LKSLINEKMT YLKNICKGTN IRIGVEIEEN
160 170 180 190 200
DIILCTYEKF NNYLNKRKLY DDNKSDKYNI KSNISSNCTN NNNNNNNLEN
210 220 230 240 250
LKNDNIIVII DEFHHINEKG RGIYIENIVS KILYMNKKRS RIKIICMSGT
260 270 280 290 300
LNNISILKKW MKAKFYISTY RPQEIKEHYV CNFNVYKKVQ DGKFYNTCNV
310 320 330 340 350
FSFNDTCYDK NVQKNESASF QNQKFYETNM MNTSECSLQY LNKDNIYNNN
360 370 380 390 400
NNIEMVGMNS SHVFMAGGQE ERKQCSGHNK RSSYNRGRSY SYEPNNNNNN
410 420 430 440 450
NKKRINCNHS SKYSSSNNNT VSYSYFSSIE ESDTINNYNS LNSMNSMNNV
460 470 480 490 500
CPSILNNNRS YSNYNNMHSS NISLTYSCNK NNYPNNMKSS AHNNMHHNIN
510 520 530 540 550
HQENYRNQNS YSHFSGHGSY IDNQHVNNND KCNYEGILNN KNQINNPIYS
560 570 580 590 600
CDNDSISNIK DSQYLSQNRY VHTEKKDSLD DHINYILKEK EKLICETNSK
610 620 630 640 650
DSIMCFLNKK NQNKNKYNTL NTSLINSLLY FALHSYINNL NTLIFCCTKK
660 670 680 690 700
MCEFYINLIN EYLNTLKSLP IPQYIDMKRK ELKEKIYNID KCIYEKMHKL
710 720 730 740 750
ISNGLCYYYS DISHSVKRLL EVAYKEKTLF LLTCTSTLSV GLNLFVDRVI
760 770 780 790 800
ISSPFVAQNF LTYTQYKQMI GRAARLKKGD SFIFVDKEYE KKMLNIFKET
810 820 830 840 850
FTNITSTMHA NTFEELEKYV IEFLCLYNEN EYISFYDVIH MFSFSLYYTE
860 870 880 890 900
TILNTLKQEM NSSPSIYTYK EGKDQKHAPT ISVKKILDSL HRDSTSTEET
910 920 930 940 950
ATKRKNHNKE DNYMGGNIYG DNNKNDDKCD DKCDDKYVEN CYTLYNNNQR
960 970 980 990 1000
GFIHGENVTP INKTEEVKKE YKNEILKENI NTSYSFYFNI NLNYFTCDEI
1010 1020 1030 1040 1050
LFYHNKKNEI YKVLDNLLKH KCIEIHNEKI KITNFCRSLC ISNLNLSIGI
1060 1070 1080 1090 1100
DLINEIRMYD KIYLYNKFHL CYICSSYNIN IVSFNYELSH IKNVLSLISD
1110 1120 1130 1140 1150
NYTKNIIFQT LKFDSDLINM LNLNSQHNQK KKTYFSNSQL ERKYSKLYLS
1160 1170 1180 1190 1200
ILLFLYLNDE DIQIICSIYK ITPDVLKSIV KHTYMYINIL ISFFDKLNEW
1210 1220 1230
ILVCLLKKFL QNFKSSKQLS IYAGKFKKGK SYDQMK
Length:1,236
Mass (Da):146,282
Last modified:March 1, 2003 - v1
Checksum:i0B7459E3C8770C17
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014187 Genomic DNA. Translation: AAN36847.1.
LN999946 Genomic DNA. Translation: CZT99949.1.
RefSeqiXP_001348408.1. XM_001348372.1.

Genome annotation databases

EnsemblProtistsiCZT99949; CZT99949; PF3D7_1425400.
GeneDBiPF3D7_1425400.1:pep.
GeneIDi811816.
KEGGipfa:PF14_0234.

Similar proteinsi

Entry informationi

Entry nameiQ8ILK9_PLAF7
AccessioniPrimary (citable) accession number: Q8ILK9
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: December 20, 2017
This is version 107 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported