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Protein
Submitted name:

DNA mismatch repair protein MSH2, putative

Gene

PF14_0254

Organism
Plasmodium falciparum (isolate 3D7)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-PFA-5358565. Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha).

Names & Taxonomyi

Protein namesi
Submitted name:
DNA mismatch repair protein MSH2, putativeImported
Submitted name:
DNA mismatch repair protein Msh2p, putativeImported
Gene namesi
ORF Names:PF14_0254Imported, PF3D7_1427500Imported
OrganismiPlasmodium falciparum (isolate 3D7)Imported
Taxonomic identifieri36329 [NCBI]
Taxonomic lineageiEukaryotaAlveolataApicomplexaAconoidasidaHaemosporidaPlasmodiidaePlasmodiumPlasmodium (Laverania)
Proteomesi
  • UP000001450 Componenti: Chromosome 14

Organism-specific databases

EuPathDBiPlasmoDB:PF3D7_1427500.

Subcellular locationi

GO - Cellular componenti

Structurei

3D structure databases

SMRiQ8ILI9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini634 – 650DNA_MISMATCH_REPAIR_2InterPro annotationAdd BLAST17

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili359 – 379Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

HOGENOMiHOG000281266.
InParanoidiQ8ILI9.
KOiK08735.
OMAiGDFYTAH.

Family and domain databases

Gene3Di3.30.420.110. 1 hit.
InterProiView protein in InterPro
IPR011184. DNA_mismatch_repair_Msh2.
IPR000432. DNA_mismatch_repair_MutS_C.
IPR007696. DNA_mismatch_repair_MutS_core.
IPR036187. DNA_mismatch_repair_MutS_sf.
IPR032642. Msh2.
IPR036678. MutS_con_dom_sf.
IPR027417. P-loop_NTPase.
PANTHERiPTHR11361:SF35. PTHR11361:SF35. 1 hit.
PfamiView protein in Pfam
PF05192. MutS_III. 1 hit.
PF00488. MutS_V. 1 hit.
PIRSFiPIRSF005813. MSH2. 1 hit.
SMARTiView protein in SMART
SM00534. MUTSac. 1 hit.
SM00533. MUTSd. 1 hit.
SUPFAMiSSF48334. SSF48334. 1 hit.
SSF52540. SSF52540. 1 hit.
PROSITEiView protein in PROSITE
PS00486. DNA_MISMATCH_REPAIR_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8ILI9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MENHEVEEVN EDQILCLYID TKKYQKSLGV CFYNYLKYEF LMTEFIDNGH
60 70 80 90 100
FTALESLFIQ KRPHKCFFNS TNDLVDDERL LNLFKICNVQ AIPLEKKKYD
110 120 130 140 150
ATNLKDELKL IISHNDDVRN YDKHLELENA CKCLMVLINY LKLKENQDIH
160 170 180 190 200
NQCKINIHNM DLYMRLDKAA ISALNILPNK KNIHSYNNNT SLLKFLDKCN
210 220 230 240 250
TTIGSKKLVS WLTQPLTNVA EINKRLNIVE FFIKEDDARN VIFCNYLKRI
260 270 280 290 300
PELDKLNHYL KEINQNNEIR VNSKYNEEMI LKDIVKMYYS ILDFKQIYFT
310 320 330 340 350
LKPIQGKNKE TIDEIIINPL RDILNKFSKL LDMIEITIDL EEVQENKVYL
360 370 380 390 400
ISTSFDNELE IIANEKNALM KKIKKHKDDV EKDIFADKYD RTYKRANRED
410 420 430 440 450
IRLVDCNTNV FLFRVTKKDC GLVQQDKKKY MTVRMNKNEF LFTTNTLKNL
460 470 480 490 500
CKQYDHCLNI YNTLQSEIIN KTICAVSTYT PVIEKFIDLV STLDVLISFS
510 520 530 540 550
VVCHNSPFPY VRPVIVDHGE NVIMRKSRHP LLELQYNLNN FIPNDIHMNK
560 570 580 590 600
KNSRLIIVTG PNMGGKSTYI RQTAIICILA QIGMFVPCDF CEVPIFTQIM
610 620 630 640 650
CRVGASDFQL KGISTFLSEM IEAAAIVKNA DQNSFIIVDE LGRGTSTYEG
660 670 680 690 700
LGISWSIGKY ILDNIKCFCL FATHFHEMSN IAYQCEGVIN RHVETTIDKE
710 720 730 740 750
KKKICFLYEI KDGASNKSYG VNVAEIAKLP KEVIQKAYEK VEELESAENK
760 770 780 790 800
YYLKEKLNID TSASADENYK MKISNYMKIK DEIHYLFSST NENEFMERFV
810
SKKNYLKELA I
Length:811
Mass (Da):94,739
Last modified:March 1, 2003 - v1
Checksum:iE17E8CEB73EE993A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014187 Genomic DNA. Translation: AAN36867.1.
LN999946 Genomic DNA. Translation: CZT99971.1.
RefSeqiXP_001348428.1. XM_001348392.1.

Genome annotation databases

EnsemblProtistsiCZT99971; CZT99971; PF3D7_1427500.
GeneDBiPF3D7_1427500.1:pep.
GeneIDi811836.
KEGGipfa:PF14_0254.

Similar proteinsi

Entry informationi

Entry nameiQ8ILI9_PLAF7
AccessioniPrimary (citable) accession number: Q8ILI9
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: December 20, 2017
This is version 100 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported