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Protein
Submitted name:

ADP-dependent DNA helicase RecQ

Gene

PF14_0278

Organism
Plasmodium falciparum (isolate 3D7)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHelicaseImported, Hydrolase
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
ADP-dependent DNA helicase RecQImported (EC:3.6.4.12Imported)
Submitted name:
ATP-dependent DNA helicase, putativeImported
Gene namesi
ORF Names:PF14_0278Imported, PF3D7_1429900Imported
OrganismiPlasmodium falciparum (isolate 3D7)Imported
Taxonomic identifieri36329 [NCBI]
Taxonomic lineageiEukaryotaAlveolataApicomplexaAconoidasidaHaemosporidaPlasmodiidaePlasmodiumPlasmodium (Laverania)
Proteomesi
  • UP000001450 Componenti: Chromosome 14

Organism-specific databases

EuPathDBiPlasmoDB:PF3D7_1429900.

Subcellular locationi

GO - Cellular componenti

Structurei

3D structure databases

SMRiQ8ILG5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini60 – 230Helicase ATP-bindingInterPro annotationAdd BLAST171
Domaini264 – 418Helicase C-terminalInterPro annotationAdd BLAST155

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili841 – 861Sequence analysisAdd BLAST21
Coiled coili1235 – 1255Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

InParanoidiQ8ILG5.

Family and domain databases

CDDicd00079. HELICc. 1 hit.
Gene3Di1.10.10.10. 1 hit.
InterProiView protein in InterPro
IPR011545. DEAD/DEAH_box_helicase_dom.
IPR004589. DNA_helicase_ATP-dep_RecQ.
IPR014001. Helicase_ATP-bd.
IPR001650. Helicase_C.
IPR010997. HRDC-like_sf.
IPR027417. P-loop_NTPase.
IPR032284. RecQ_Zn-bd.
IPR018982. RQC_domain.
IPR036388. WH-like_DNA-bd_sf.
IPR036390. WH_DNA-bd_sf.
PfamiView protein in Pfam
PF00270. DEAD. 1 hit.
PF00271. Helicase_C. 1 hit.
PF16124. RecQ_Zn_bind. 1 hit.
PF09382. RQC. 1 hit.
SMARTiView protein in SMART
SM00487. DEXDc. 1 hit.
SM00490. HELICc. 1 hit.
SM00956. RQC. 1 hit.
SUPFAMiSSF46785. SSF46785. 1 hit.
SSF47819. SSF47819. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00614. recQ_fam. 1 hit.
PROSITEiView protein in PROSITE
PS51192. HELICASE_ATP_BIND_1. 1 hit.
PS51194. HELICASE_CTER. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8ILG5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLKFLNVKSP VVSSDVDEIT DDSDKGDVSY TLEELRMKME ITQKKHFGYK
60 70 80 90 100
NLKDFQVEAV HATFHKKDSF IVMATGMGKS LCYQIPSLMD VCRKKFTIVI
110 120 130 140 150
SPLISLMKDQ VDNLNRKRIS SVFLGSGQKM NNNKILNEIK HGIYKIVYCS
160 170 180 190 200
PEYALNNKDV FILLKNRILL IAIDEVHCMS EWGHDFRPSY RKLNELRIIL
210 220 230 240 250
KEIPIMCLTA TCTKNVQSDI LKNLNFDLQN CLIKRSSVNK KNLFYSVREK
260 270 280 290 300
TDIYHDLKDI LDIPLKESIE RTKKFIDNSK ICSYNSTLIY VNSKKECESV
310 320 330 340 350
YSFLKEKGLL VLMYHADLTN DQKKEAHEKF LKDEIQIIVA TVAFGMGIDK
360 370 380 390 400
PDIRRIIHYG FARSLEAYVQ QVGRAGRDNS DAEAILFFHI NDESKIKNII
410 420 430 440 450
LRENTANNLI ETNFQRVEHI VHIFTQASDY AYSTACRRKK IYEYFDEAPL
460 470 480 490 500
TSYDIDIFND KRNEGICYYI KKYDIYLCGK CDNCVYCLNL IKKKNGIKTN
510 520 530 540 550
KINNNNNNNI NIYSNSNNNN NINSNNNSRE YYLDNDIKKE TSLKSLTCYY
560 570 580 590 600
ISSSSNSSFS SYIFDNVVDL TNELKTLLNC ISSLKGKTGL STVCKILVKS
610 620 630 640 650
KESSIIKKNY HNIKEYGKGA HKSTNWWSSF MKVVRNDKFI KETLNCGKEM
660 670 680 690 700
CYISVGVTDK GEEFIQSKEK YIIALPFFLN TSPKSSNTRN KKTKKDTYGK
710 720 730 740 750
YSNNKETKYE NITYEYKDKY NDNDNDKDND NDNDNDNDYS KDIYNVDDYK
760 770 780 790 800
YDDHHISSKI KQQQEQHNNN IRDIYYNDKD VEYDKSIHNI NKNTNKNLSY
810 820 830 840 850
ITIESGDEKG NTNCIINKEN INRDNNFEKT HKNNIEKYEY IESYQKQKNN
860 870 880 890 900
NKNNNIQINN KKYDDNKYEY FNINKNDFIM KENRYTKEEK ILSDEQINDS
910 920 930 940 950
IMKILLRTRM LEARKQNIPP FQLISDQPLK DICHKRLTSV ELIRKHVYNI
960 970 980 990 1000
SPICPNTFLE KIVSGIRGFC LLHDLKTDIL NLNIYNPNHN NSPIPINAKT
1010 1020 1030 1040 1050
STLKNFENLI SSYNYYDRNK YAPREESKSN ETYSYEHYTG TERKCKHFVT
1060 1070 1080 1090 1100
QEDEYNHADI SKMSRHTNIY EHKKNMNDHT YDLHNYNNNI TYDYGDIPKN
1110 1120 1130 1140 1150
TLIQYKNSLT DQNTISMSDI NSDNKNMVYN NHIFNKNHSI ITNYNSSAEN
1160 1170 1180 1190 1200
NSSLQNEFYR KKTNIIDDNN IGHHTYNIND NYHTNDVLLT NAIIKDRPKK
1210 1220 1230 1240 1250
KHDDIFSNFC YKRDESETGV QGNVTHVKKD INKGYQENKN DITFLQNNIS
1260 1270 1280 1290 1300
QHTNNMIHNN GKDVKNNLSA LDDDDDDDDD DFKFINQIQT LGLHEQNCKE
1310 1320 1330 1340 1350
ENNYQNSLTN EHVHIPNYNL YQEENTRNEN EKRKININLK QEDQNIYTKR
1360 1370 1380 1390 1400
HQYLTNPNEH SVNNMHNIHL KENNIPKYDY TNQNVHESNQ KKNDFYEEKK
1410 1420 1430 1440
KKFNFIESFS YNNNQEDKKR VNNLDILDQF VYRDVKKRKT
Length:1,440
Mass (Da):169,541
Last modified:March 1, 2003 - v1
Checksum:i98CA2A9F146A5B6A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014187 Genomic DNA. Translation: AAN36891.1.
LN999946 Genomic DNA. Translation: CZT99996.1.
RefSeqiXP_001348452.1. XM_001348416.1.

Genome annotation databases

EnsemblProtistsiCZT99996; CZT99996; PF3D7_1429900.
GeneDBiPF3D7_1429900.1:pep.
GeneIDi811860.
KEGGipfa:PF14_0278.

Similar proteinsi

Entry informationi

Entry nameiQ8ILG5_PLAF7
AccessioniPrimary (citable) accession number: Q8ILG5
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: December 20, 2017
This is version 121 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported