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Q8IL98

- Q8IL98_PLAF7

UniProt

Q8IL98 - Q8IL98_PLAF7

Protein

ATP-dependent Clp protease proteolytic subunit

Gene

PF14_0348

Organism
Plasmodium falciparum (isolate 3D7)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 68 (01 Oct 2014)
      Sequence version 1 (01 Mar 2003)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. serine-type endopeptidase activity Source: GeneDB_Pfalciparum

    GO - Biological processi

    1. proteolysis Source: GeneDB_Pfalciparum

    Keywords - Molecular functioni

    Hydrolase, ProteaseImported

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    ATP-dependent Clp protease proteolytic subunitUniRule annotation
    Gene namesi
    ORF Names:PF14_0348Imported
    OrganismiPlasmodium falciparum (isolate 3D7)Imported
    Taxonomic identifieri36329 [NCBI]
    Taxonomic lineageiEukaryotaAlveolataApicomplexaAconoidasidaHaemosporidaPlasmodiumPlasmodium (Laverania)
    ProteomesiUP000001450: Chromosome 14

    Organism-specific databases

    EuPathDBiPlasmoDB:PF3D7_1436800.

    Subcellular locationi

    GO - Cellular componenti

    1. apicoplast Source: GeneDB_Pfalciparum

    Interactioni

    Protein-protein interaction databases

    STRINGi5833.PF14_0348-1.

    Structurei

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    4GM2X-ray2.80A/B/C/D/E/F/G61-244[»]
    4HNKX-ray2.90A/B/C/D/E/F/G/H/I/J/K/L/M/N49-244[»]
    ProteinModelPortaliQ8IL98.
    SMRiQ8IL98. Positions 61-243.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the peptidase S14 family.UniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000285833.
    KOiK01358.
    OMAiYGDSAVM.
    PhylomeDBiQ8IL98.

    Family and domain databases

    Gene3Di3.90.226.10. 1 hit.
    InterProiIPR001907. ClpP.
    IPR029045. ClpP/crotonase-like_dom.
    IPR023562. ClpP/TepA.
    [Graphical view]
    PANTHERiPTHR10381. PTHR10381. 1 hit.
    PfamiPF00574. CLP_protease. 1 hit.
    [Graphical view]
    PRINTSiPR00127. CLPPROTEASEP.
    SUPFAMiSSF52096. SSF52096. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q8IL98-1 [UniParc]FASTAAdd to Basket

    « Hide

    MQGLLLFMLI CINFCKCTKI ITRYNFITNK INIKRYKKKN NNKSPLYYSY    50
    NEHHKYNINI PSLLLSKRII FLSSPIYPHI SEQIISQLLY LEYESKRKPI 100
    HLYINSTGDI DNNKIINLNG ITDVISIVDV INYISSDVYT YCLGKAYGIA 150
    CILASSGKKG YRFSLKNSSF CLNQSYSIIP FNQATNIEIQ NKEIMNTKKK 200
    VIEIISKNTE KDTNVISNVL ERDKYFNADE AVDFKLIDHI LEKE 244
    Length:244
    Mass (Da):28,325
    Last modified:March 1, 2003 - v1
    Checksum:iF3BCBDB584F25DF2
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE014187 Genomic DNA. Translation: AAN36961.1.
    RefSeqiXP_001348522.1. XM_001348486.1.

    Genome annotation databases

    EnsemblProtistsiPF14_0348:mRNA; PF14_0348:pep; PF14_0348.
    GeneIDi811930.
    KEGGipfa:PF14_0348.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE014187 Genomic DNA. Translation: AAN36961.1 .
    RefSeqi XP_001348522.1. XM_001348486.1.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    4GM2 X-ray 2.80 A/B/C/D/E/F/G 61-244 [» ]
    4HNK X-ray 2.90 A/B/C/D/E/F/G/H/I/J/K/L/M/N 49-244 [» ]
    ProteinModelPortali Q8IL98.
    SMRi Q8IL98. Positions 61-243.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 5833.PF14_0348-1.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblProtistsi PF14_0348:mRNA ; PF14_0348:pep ; PF14_0348 .
    GeneIDi 811930.
    KEGGi pfa:PF14_0348.

    Organism-specific databases

    EuPathDBi PlasmoDB:PF3D7_1436800.

    Phylogenomic databases

    HOGENOMi HOG000285833.
    KOi K01358.
    OMAi YGDSAVM.
    PhylomeDBi Q8IL98.

    Family and domain databases

    Gene3Di 3.90.226.10. 1 hit.
    InterProi IPR001907. ClpP.
    IPR029045. ClpP/crotonase-like_dom.
    IPR023562. ClpP/TepA.
    [Graphical view ]
    PANTHERi PTHR10381. PTHR10381. 1 hit.
    Pfami PF00574. CLP_protease. 1 hit.
    [Graphical view ]
    PRINTSi PR00127. CLPPROTEASEP.
    SUPFAMi SSF52096. SSF52096. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Isolate 3D7Imported.
    2. "Structural insights into the inactive subunit of the apicoplast-localized caseinolytic protease complex of Plasmodium falciparum."
      El Bakkouri M., Rathore S., Calmettes C., Wernimont A.K., Liu K., Sinha D., Asad M., Jung P., Hui R., Mohmmed A., Houry W.A.
      J. Biol. Chem. 288:1022-1031(2013) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (2.80 ANGSTROMS) OF 61-244.

    Entry informationi

    Entry nameiQ8IL98_PLAF7
    AccessioniPrimary (citable) accession number: Q8IL98
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 1, 2003
    Last sequence update: March 1, 2003
    Last modified: October 1, 2014
    This is version 68 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    3D-structureImported, Complete proteome, Reference proteomeImported

    External Data

    Dasty 3