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Protein
Submitted name:

DEAD/DEAH box helicase, putative

Gene

PF14_0370

Organism
Plasmodium falciparum (isolate 3D7)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  • ATP binding Source: InterPro
  • ATP-dependent RNA helicase activity Source: GeneDB
  • nucleic acid binding Source: InterPro

Keywordsi

Molecular functionHelicaseImported, Hydrolase
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
DEAD/DEAH box helicase, putativeImported
Gene namesi
ORF Names:PF14_0370Imported, PF3D7_1439100Imported
OrganismiPlasmodium falciparum (isolate 3D7)Imported
Taxonomic identifieri36329 [NCBI]
Taxonomic lineageiEukaryotaAlveolataApicomplexaAconoidasidaHaemosporidaPlasmodiidaePlasmodiumPlasmodium (Laverania)
Proteomesi
  • UP000001450 Componenti: Chromosome 14

Organism-specific databases

EuPathDBiPlasmoDB:PF3D7_1439100.

Structurei

3D structure databases

SMRiQ8IL78.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini349 – 648Helicase ATP-bindingInterPro annotationAdd BLAST300
Domaini682 – 895Helicase C-terminalInterPro annotationAdd BLAST214
Domaini1380 – 1556Helicase ATP-bindingInterPro annotationAdd BLAST177
Domaini1774 – 1950Helicase C-terminalInterPro annotationAdd BLAST177

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili201 – 228Sequence analysisAdd BLAST28
Coiled coili1107 – 1127Sequence analysisAdd BLAST21
Coiled coili1511 – 1531Sequence analysisAdd BLAST21
Coiled coili1731 – 1751Sequence analysisAdd BLAST21
Coiled coili2327 – 2351Sequence analysisAdd BLAST25

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

HOGENOMiHOG000282165.
InParanoidiQ8IL78.
OMAiCIRTEAT.

Family and domain databases

CDDicd00079. HELICc. 2 hits.
Gene3Di2.60.40.150. 2 hits.
InterProiView protein in InterPro
IPR003593. AAA+_ATPase.
IPR035892. C2_domain_sf.
IPR011545. DEAD/DEAH_box_helicase_dom.
IPR014001. Helicase_ATP-bd.
IPR001650. Helicase_C.
IPR014756. Ig_E-set.
IPR027417. P-loop_NTPase.
IPR004179. Sec63-dom.
IPR036390. WH_DNA-bd_sf.
PfamiView protein in Pfam
PF00270. DEAD. 2 hits.
PF00271. Helicase_C. 2 hits.
PF02889. Sec63. 2 hits.
SMARTiView protein in SMART
SM00382. AAA. 2 hits.
SM00487. DEXDc. 2 hits.
SM00490. HELICc. 2 hits.
SM00973. Sec63. 2 hits.
SUPFAMiSSF46785. SSF46785. 3 hits.
SSF52540. SSF52540. 6 hits.
SSF81296. SSF81296. 1 hit.
PROSITEiView protein in PROSITE
PS51192. HELICASE_ATP_BIND_1. 2 hits.
PS51194. HELICASE_CTER. 2 hits.

Sequencei

Sequence statusi: Complete.

Q8IL78-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKERINEKFK INSYQDYSDK NNEWNIDDAI NYIKRNAFFK KYKDINDVND
60 70 80 90 100
ICDINVDDHI NDDDKFYQNF ENILIEEKKY LKKLLRENRW NDNILKEYVD
110 120 130 140 150
GKVLENEENE ESGLMYVYNT CYNILSSKNE ITDINNKDNS IINHSNYNEG
160 170 180 190 200
YIIINKNNTM KKIYINEINE LLIEIIYITL TRENLENSLV DLLGDRFLDF
210 220 230 240 250
IIQIIKNKEQ IEKDIKLLSK QIVIKENTLV SNFFITNKSS KKIKNQQILY
260 270 280 290 300
KKENIEKIID HFLYLLTDDS YNQMKKIYIP NDQDKLEEIH VPKNTIYSYT
310 320 330 340 350
DNITKVKISR LENLQFHKKE LVSVNVLPFW HKYIFDFEYF NYVQSKVFNS
360 370 380 390 400
AFRSNKNLLV CAPTGCGKTN IALLVILQQI ILFCEQNKIK LEKIVKSYLI
410 420 430 440 450
KNGLLSCDED IKKRNDDNER TRDELKSYGY NEPNNYVDNN NNNNSDNDDN
460 470 480 490 500
NNININSEGE DEGDIIHLSD NGDKNFDDDN NFDDYDDDVD GDGENYCGYI
510 520 530 540 550
NSKEFKIIYI APMKSLVFEI TNLFRKKLKI FNLNVCEYTK EYSLSSKELE
560 570 580 590 600
QVHIIVTVPE KLDILLRNSS YSTTVSDESL IKYIKCLILD EVHLLNTDRG
610 620 630 640 650
DVIETIVSRF LQYSETSQSI RRIMAMSATL PNYKDVRDFL KVENDMCYYF
660 670 680 690 700
NEKYRSIQLD KTLYGIHEEN NNKLYIAKNI YTYNEIINSL KKDKQCIIFV
710 720 730 740 750
CSRNETNKTI EFLINHALKN NEIEYFVNNV YTDNDIKKKI KKSNNLYIKQ
760 770 780 790 800
FYEYGCTIHH AGMSRSDKIL VESLFKKKVF NVLCCTSTLA WGVNLPVHTV
810 820 830 840 850
IIKGTNYFSS ESGKLEDMDI LDINQIFGRC GRPQYESHGH AILITERTKL
860 870 880 890 900
YKYIKLLTNN TVIESNFLKN IENHLNAEIS IGTIKNIEDG IKWLEYTYLF
910 920 930 940 950
IRMKKNPYLY DVDINNDLNL YNKRKDIIMK AIQNLSENKL VRRVLLTNDF
960 970 980 990 1000
IGTFYGQIAA KYYVDYKTIG MFAENVQNNN YIEIIQVISK AKEFENIQIR
1010 1020 1030 1040 1050
NEDMKDFLYL KDKCDIKEEY DESKNMTLRI LIEVYLRRLQ INNFSIICEI
1060 1070 1080 1090 1100
NYIVQNIIRI LYAYYDICLN ILKNISNLIM NTHNLIVAIL RRLPINCGIF
1110 1120 1130 1140 1150
RHFCYKNEML EKNKKAILTN KDRLKNIKKD NEESDKKNNI SDRNVGVHLI
1160 1170 1180 1190 1200
DINEENEYSN TYNNYSNNNR RNQNYTVYLK EAAVNILEKK NLTYESIEHL
1210 1220 1230 1240 1250
SKKELLFFMR NEIYTNQILY YRNIIPNLDI DGYIQPITQT IMKINLNVKL
1260 1270 1280 1290 1300
TNTIWSDQWN DIIENFHIFL LNTLNNDILY FQKFSIHKKD RKKIHDISFE
1310 1320 1330 1340 1350
FPLSNQIPPQ ITVQFLSMNW CNLSFVHIFN TNNLFINQKI NVFSEILPLT
1360 1370 1380 1390 1400
PLSTNVLNIP NYIKFFSFKY FNPIQTQMFH ATFHTDENIL LGAPTGSGKT
1410 1420 1430 1440 1450
VIGELCILRN LLRCEGQKSV YICPMKAIVN ERYKSWKSKF KSLFNKNVIE
1460 1470 1480 1490 1500
LTGDKNENKE NIAESNIIIC TPEKLDVITR NWKNKKFVKN INLIIFDEIH
1510 1520 1530 1540 1550
LLGQENRGGV IEILVNRFKN MQNELNKKIR LIGLTTVITS VDDLILWLDV
1560 1570 1580 1590 1600
KENYLFNFPS SCRIVPCKTH ILGFTQKAYC NRMSVMNKNV FDAINQYAQT
1610 1620 1630 1640 1650
KNVLIFVSSR RQTRLTAYDI ISLNLSSHNL NFLHVENLLN DKNHIDFLLN
1660 1670 1680 1690 1700
TQKKNKKNKI NNKDMNEGDN NIAENINTFE YTEYKMNINR KDNIASYNNM
1710 1720 1730 1740 1750
SYYHKSSVTD EHNINQCNNN DDNNKGFFGY MKKKTLGNDK IKKEYKQYNN
1760 1770 1780 1790 1800
EDDNKIHNNY YNNNFCDNEI YDYNLLFNNS KLSEEERKNV ANILFQNYLN
1810 1820 1830 1840 1850
LIENEHLKEI LKYGIGIHHA GLNENDKTIV EYLFLNKIIQ ILICTSTLAW
1860 1870 1880 1890 1900
GINLPAYLVI IKGNEFYDAK TKKYKDIPYT DLLQMIGRAG RPQFDDKALA
1910 1920 1930 1940 1950
ILLVQEKRKN AIKNFLYHPM NIESNIMENF NEHINAEICS NVINNKEDIF
1960 1970 1980 1990 2000
NYLTKSYYFK RLFSNPSYYI KEVQYVQFFE NSKLSTHAKK IIYDHLNDVI
2010 2020 2030 2040 2050
ENGIKFLVQN KCLEVVQENY VLNYYATPLG HIASMYYIKC ETVYFFYTSI
2060 2070 2080 2090 2100
QAGKKHKNDK MNNMNSTKID DNTMDHVDSI NGDDDKENHV DSLNVEAIKM
2110 2120 2130 2140 2150
NDMDNTNGNN NNNNNNTNAV NNNINGDIDK LNDNMQTDFC TLKNDSLEFY
2160 2170 2180 2190 2200
DIFELVVQAK EFDDIPLRHN EDKYNVKLRN QIPLDIDMNM PNVKTYLLLL
2210 2220 2230 2240 2250
SRFYECTYET VDYHIDLKLV MDQIARVINA FIDICLLFHN YNYIKKLILI
2260 2270 2280 2290 2300
FNCINQKVKP NTNSLYIIKD ITEYQIYKLK QLDIYNINQL IKFDKSYLYS
2310 2320 2330 2340 2350
LNIFDITQIN FILQLPVFNM NVKLFYKDIH SENENEKEKE KENKNEEKNR
2360 2370 2380 2390 2400
NTTNSYVNIP YAQHFRNQHK YSFKINSYYS KEIVIKLFFN FMNRTGKEAS
2410 2420 2430 2440 2450
SQNVQWFAIL HDTEQDESIS IKRFNNNNLK KVSVISFTLE DMEKGKYNFV
2460 2470
IYIHNDTYYG IEHEVHIDLC IE
Length:2,472
Mass (Da):292,299
Last modified:March 1, 2003 - v1
Checksum:iBED2AA455120A1B9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014187 Genomic DNA. Translation: AAN36983.1.
LN999946 Genomic DNA. Translation: CZU00087.1.
RefSeqiXP_001348544.1. XM_001348508.1.

Genome annotation databases

EnsemblProtistsiCZU00087; CZU00087; PF3D7_1439100.
GeneDBiPF3D7_1439100.1:pep.
GeneIDi811952.
KEGGipfa:PF14_0370.

Similar proteinsi

Entry informationi

Entry nameiQ8IL78_PLAF7
AccessioniPrimary (citable) accession number: Q8IL78
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: December 20, 2017
This is version 112 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported