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Protein
Submitted name:

HSP90

Gene

PF14_0417

Organism
Plasmodium falciparum (isolate 3D7)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • ATPase activity, coupled Source: GeneDB
  • ATP binding Source: InterPro
  • unfolded protein binding Source: InterPro

GO - Biological processi

  • protein folding Source: InterPro
  • response to heat Source: GeneDB

Keywordsi

Biological processStress responseImported

Names & Taxonomyi

Protein namesi
Submitted name:
HSP90Imported
Submitted name:
Heat shock protein 90, putativeImported
Gene namesi
ORF Names:PF14_0417Imported, PF3D7_1443900Imported
OrganismiPlasmodium falciparum (isolate 3D7)Imported
Taxonomic identifieri36329 [NCBI]
Taxonomic lineageiEukaryotaAlveolataApicomplexaAconoidasidaHaemosporidaPlasmodiidaePlasmodiumPlasmodium (Laverania)
Proteomesi
  • UP000001450 Componenti: Chromosome 14

Organism-specific databases

EuPathDBiPlasmoDB:PF3D7_1443900

Pathology & Biotechi

Chemistry databases

ChEMBLiCHEMBL1795086

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1Y6ZX-ray1.88A/B385-645[»]
3IEDX-ray2.01A97-347[»]
SMRiQ8IL32
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ8IL32

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili167 – 194Sequence analysisAdd BLAST28
Coiled coili643 – 663Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

HOGENOMiHOG000031988
InParanoidiQ8IL32
OMAiFDEESRG

Family and domain databases

CDDicd00075 HATPase_c, 1 hit
Gene3Di1.20.120.790, 1 hit
3.30.565.10, 1 hit
HAMAPiMF_00505 HSP90, 1 hit
InterProiView protein in InterPro
IPR003594 HATPase_C
IPR036890 HATPase_C_sf
IPR019805 Heat_shock_protein_90_CS
IPR037196 HSP90_C
IPR001404 Hsp90_fam
IPR020575 Hsp90_N
IPR020568 Ribosomal_S5_D2-typ_fold
PANTHERiPTHR11528 PTHR11528, 1 hit
PfamiView protein in Pfam
PF00183 HSP90, 1 hit
PRINTSiPR00775 HEATSHOCK90
SUPFAMiSSF110942 SSF110942, 1 hit
SSF54211 SSF54211, 1 hit
SSF55874 SSF55874, 2 hits
PROSITEiView protein in PROSITE
PS00298 HSP90, 1 hit

Sequencei

Sequence statusi: Complete.

Q8IL32-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQNVYVGNKI KFIILYFFCV LFLKDYERSE AFNLARTTEK LNYILNYKTP
60 70 80 90 100
NRYDLNNNVN KLFFEKQKKK IEFSRKPLNS FNEDVKTIRE DISSDSSPVE
110 120 130 140 150
KYNFKAEVNK VMDIIVNSLY TDKDVFLREL ISNASDACDK KRIILENNKL
160 170 180 190 200
IKDAEVVTNE EIKNETEKEK TENVNESTDK KENVEEEKND IKKLIIKIKP
210 220 230 240 250
DKEKKTLTIT DNGIGMDKSE LINNLGTIAQ SGTAKFLKQI EEGKADSNLI
260 270 280 290 300
GQFGVGFYSS FLVSNRVEVY TKKEDQIYRW SSDLKGSFSV NEIKKYDQEY
310 320 330 340 350
DDIKGSGTKI ILHLKEECDE YLEDYKLKEL IKKYSEFIKF PIEIWSEKID
360 370 380 390 400
YERVPDDSVS LKDGDKMKMK TITKRYHEWE KINVQLPIWK QDEKSLTEND
410 420 430 440 450
YYSFYKNTFK AYDDPLAYVH FNVEGQISFN SILYIPGSLP WELSKNMFDE
460 470 480 490 500
ESRGIRLYVK RVFINDKFSE SIPRWLTFLR GIVDSENLPL NVGREILQKS
510 520 530 540 550
KMLSIINKRI VLKSISMMKG LKETGGDKWT KFLNTFGKYL KIGVVEDKEN
560 570 580 590 600
QEEIASLVEF YSINSGDKKT DLDSYIENMK EDQKCIYYIS GENKKTAQNS
610 620 630 640 650
PSLEKLKALN YDVLFSLEPI DEFCLSSLTV NKYKGYEVLD VNKADLKLKK
660 670 680 690 700
ENDQNKSDSL DKQKMEYEIL CRWLHNKFSH KVHEVRISDR LINSPALLVQ
710 720 730 740 750
GEMGMSPSMQ KYMKQQATAQ GISENEMFGG QSANQPVLEI NPNHFIIKQL
760 770 780 790 800
NHLIQIDKMN LQNSEIAEQI FDVASMQGGY TIDDTGLFAK RVIGMMEKNA
810 820 830 840 850
EQYLMNVQSN ISNNTLNNNT SGSEMPQNNS PNELQSEMKS TNGIDDNSNI
860 870 880 890 900
SENKINESSS NQNNIGENSI AEENNIKNIA ESDVNKINLG ENDVSQNTMH
910 920
KQDSGLFNLD PSILNSNMLS GSDKTLL
Length:927
Mass (Da):106,999
Last modified:March 1, 2003 - v1
Checksum:iA8A40CCB402AAF25
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014187 Genomic DNA Translation: AAN37030.1
LN999946 Genomic DNA Translation: CZU00135.1
RefSeqiXP_001348591.1, XM_001348555.1

Genome annotation databases

EnsemblProtistsiCZU00135; CZU00135; PF3D7_1443900
GeneDBiPF3D7_1443900.1:pep
GeneIDi811999
KEGGipfa:PF14_0417

Similar proteinsi

Entry informationi

Entry nameiQ8IL32_PLAF7
AccessioniPrimary (citable) accession number: Q8IL32
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: March 28, 2018
This is version 130 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health