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Protein
Submitted name:

ATP-dependent RNA helicase DDX5, putative

Gene

PF14_0437

Organism
Plasmodium falciparum (isolate 3D7)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

  • ATP binding Source: UniProtKB-KW
  • ATP-dependent RNA helicase activity Source: GO_Central
  • helicase activity Source: GeneDB
  • nucleic acid binding Source: GeneDB

GO - Biological processi

Keywordsi

Molecular functionHelicaseUniRule annotationImported, Hydrolase
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
ATP-dependent RNA helicase DDX5, putativeImported (EC:3.6.4.13Imported)
Submitted name:
Helicase, putativeImported
Gene namesi
ORF Names:PF14_0437Imported, PF3D7_1445900Imported
OrganismiPlasmodium falciparum (isolate 3D7)Imported
Taxonomic identifieri36329 [NCBI]
Taxonomic lineageiEukaryotaAlveolataApicomplexaAconoidasidaHaemosporidaPlasmodiidaePlasmodiumPlasmodium (Laverania)
Proteomesi
  • UP000001450 Componenti: Chromosome 14

Organism-specific databases

EuPathDBiPlasmoDB:PF3D7_1445900.

Subcellular locationi

GO - Cellular componenti

Interactioni

Protein-protein interaction databases

IntActiQ8IL13. 2 interactors.
MINTiMINT-1661155.

Structurei

3D structure databases

SMRiQ8IL13.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini113 – 141Q_MOTIFInterPro annotationAdd BLAST29
Domaini144 – 319Helicase ATP-bindingInterPro annotationAdd BLAST176
Domaini348 – 494Helicase C-terminalInterPro annotationAdd BLAST147

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi113 – 141Q motifPROSITE-ProRule annotationAdd BLAST29

Sequence similaritiesi

Belongs to the DEAD box helicase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000199241.
InParanoidiQ8IL13.
KOiK12823.
OMAiFDYPSCS.

Family and domain databases

CDDicd00079. HELICc. 1 hit.
InterProiView protein in InterPro
IPR011545. DEAD/DEAH_box_helicase_dom.
IPR014001. Helicase_ATP-bd.
IPR001650. Helicase_C.
IPR027417. P-loop_NTPase.
IPR000629. RNA-helicase_DEAD-box_CS.
IPR014014. RNA_helicase_DEAD_Q_motif.
PfamiView protein in Pfam
PF00270. DEAD. 1 hit.
PF00271. Helicase_C. 1 hit.
SMARTiView protein in SMART
SM00487. DEXDc. 1 hit.
SM00490. HELICc. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiView protein in PROSITE
PS00039. DEAD_ATP_HELICASE. 1 hit.
PS51192. HELICASE_ATP_BIND_1. 1 hit.
PS51194. HELICASE_CTER. 1 hit.
PS51195. Q_MOTIF. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8IL13-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRGFNYNNNS NNNNRYSAYP DYNNSYGNYQ AYGQQYRANY GTGYVPNYNN
60 70 80 90 100
NSNNYGKNLA PIDWKTINLV PFEKNFYKEH EDISKLSTKE VKEIRDKHKI
110 120 130 140 150
TILEGENVPK PVVSINKIGF PDYVIKSLKN NNIVAPTPIQ IQGWPIALSG
160 170 180 190 200
KDMIGKAETG SGKTLAFILP AFVHILAQPN LKYGDGPIVL VLAPTRELAE
210 220 230 240 250
QIRQECIKFS TESKIRNTCA YGGVPKSGQI YALKQGVHIL IACPGRLIDL
260 270 280 290 300
LEQNVTNLMR VTYLVLDEAD KMLDMGFELQ IRKIVDQIRP DRQTLMWSAT
310 320 330 340 350
WPKEVQALAK DLCKEQPIQV NVGSLTLTAC RSIKQEIYLL EEHEKIGNLK
360 370 380 390 400
SLLQRIFKDN DRIIVFVETK KNADFITKAL RLDGMPALCI HGDKKQEERR
410 420 430 440 450
WVLNEFKTGK SPIMIATDVA SRGLDIKNVK YVINFDFPNQ IEDYVHRIGR
460 470 480 490 500
TGRAGSHGAS FTFLTADKYR LAKDLVKILR ESEQPVPPQL EKISYSMGNN
510 520
QRRNPYYSSG RSNNVNNIPL RGNNRFY
Length:527
Mass (Da):60,036
Last modified:September 22, 2009 - v2
Checksum:iABE7819BF8838C84
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014187 Genomic DNA. Translation: AAN37050.2.
LN999946 Genomic DNA. Translation: CZU00155.1.
RefSeqiXP_001348611.2. XM_001348575.2.

Genome annotation databases

EnsemblProtistsiCZU00155; CZU00155; PF3D7_1445900.
GeneDBiPF3D7_1445900.1:pep.
GeneIDi812019.
KEGGipfa:PF14_0437.

Similar proteinsi

Entry informationi

Entry nameiQ8IL13_PLAF7
AccessioniPrimary (citable) accession number: Q8IL13
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: September 22, 2009
Last modified: December 20, 2017
This is version 108 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported