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Protein
Submitted name:

Crossover junction endonuclease MUS81, putative

Gene

PF14_0470

Organism
Plasmodium falciparum (isolate 3D7)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionEndonucleaseImported, Hydrolase, Nuclease

Names & Taxonomyi

Protein namesi
Submitted name:
Crossover junction endonuclease MUS81, putativeImported
Submitted name:
DNA replication related protein, putativeImported
Gene namesi
ORF Names:PF14_0470Imported, PF3D7_1449400Imported
OrganismiPlasmodium falciparum (isolate 3D7)Imported
Taxonomic identifieri36329 [NCBI]
Taxonomic lineageiEukaryotaAlveolataApicomplexaAconoidasidaHaemosporidaPlasmodiidaePlasmodiumPlasmodium (Laverania)
Proteomesi
  • UP000001450 Componenti: Chromosome 14

Organism-specific databases

EuPathDBiPlasmoDB:PF3D7_1449400.

Subcellular locationi

GO - Cellular componenti

Interactioni

Protein-protein interaction databases

IntActiQ8IKY1. 1 interactor.
MINTiMINT-1655910.

Structurei

3D structure databases

SMRiQ8IKY1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini849 – 1081ERCC4InterPro annotationAdd BLAST233

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili429 – 462Sequence analysisAdd BLAST34
Coiled coili597 – 625Sequence analysisAdd BLAST29
Coiled coili910 – 930Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

InParanoidiQ8IKY1.
OMAiQLRLINM.

Family and domain databases

Gene3Di1.10.150.110. 1 hit.
InterProiView protein in InterPro
IPR027421. DNA_pol_lamdba_lyase_dom_sf.
IPR006166. ERCC4_domain.
IPR011335. Restrct_endonuc-II-like.
PfamiView protein in Pfam
PF02732. ERCC4. 1 hit.
SMARTiView protein in SMART
SM00891. ERCC4. 1 hit.
SUPFAMiSSF47802. SSF47802. 1 hit.
SSF52980. SSF52980. 2 hits.

Sequencei

Sequence statusi: Complete.

Q8IKY1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDRNCNYMNK IINSKNRRHY SMHPENAIFF DYFINLKKKA IAQGYNNLVI
60 70 80 90 100
SFKKIISSIT KYPLPIKNSL DAYKLKGVGK RFSNYFEKAL SQSKVDKKIQ
110 120 130 140 150
NLKEDFISSK SEFRINIHIN KVINSADKFL KDFDKEIYNI RVLGELSDDN
160 170 180 190 200
ILNNIREIEN DNLCNVNSKN LNQCTLVSSN KLNESYSNGK SLSLCTNNIE
210 220 230 240 250
KVTSLNNNKK KKCIDMNDTE KSIITYLYKY GHLYNEHALS KEEIISGVLK
260 270 280 290 300
YYERSIVVNY KTLRRLINRE FIEKTESVEN RICNNIKSSK IKTKLKVINK
310 320 330 340 350
IRLTKKGKDF LDNEKDYILD CSLINTENIY QLNNTKEEES MLHTENVKNM
360 370 380 390 400
ISQYSFNTDN ELKEEDNNMS SKKKIDSPSY MKKNLRCSDT EEKCFELSEK
410 420 430 440 450
KENQERCLNV TYLSISKNNE IISHECLFKN ENEMEKNDEE EKNDEKKKND
460 470 480 490 500
EMNNKQNRQE NISINNIQTS DAVLVQKEEK EEFSECNQLF KNTKTLSSSS
510 520 530 540 550
YTNYSISFGF NDDIKKKTDS SWNNKKGRIY KKYKPRIFTK TKEIIEEDKN
560 570 580 590 600
KILKKKKKSI NNEESIDSKS VSILSDNYEE RKKTDGNVNG LNLSNSYDLI
610 620 630 640 650
EKKIKNIKKR MNKNLKERLE KKKKNRNDSG VSSSEMFEGS SSKEENFFSS
660 670 680 690 700
DRKKLSLEEE DKSLKLTNYI WDEDQVEEKK GEKTETKFLI KEYEKYYNEI
710 720 730 740 750
DESKKMKSFV TDELIYKSTV LKNNSKNIIK EVEDSNMLLS NVQKDTNHLR
760 770 780 790 800
EEEFLSLRNE NVNSINNNDD KEKGKKCKRK RSILNNIGNN KDAEGNKRKK
810 820 830 840 850
KKRSKPETEN KVEFDTSNIN NLNKEDKDLN EMNESNQRCK ITYGTYEIIM
860 870 880 890 900
IIDNREVTGS SYEFNEKMKK VFNDKNIKYE TRNLPLGDII WICRRSVYNK
910 920 930 940 950
NSSSNKKKQM KKMRRNKKMM DDEKKKKSEE INMDIKKGIL ERNNHSVSKE
960 970 980 990 1000
NDYHQISDDD NDDNNDDNND DNNDDNNDDH NDDHNDDHNN DHNDDHNNDD
1010 1020 1030 1040 1050
DNIDDDNNNK KKEKVLCPDK KIEPFIDDVE YEEFVLKWII ERKTLNDLSA
1060 1070 1080 1090 1100
SIIDGRYDEQ KYRMMRLRDI HHIIYLIENC NNTYRNYMNS SKISYETLNN
1110 1120 1130 1140 1150
AQHSTQLVSG FSILGSQHMN HTLFLLCEIH QEIIKHIKLY CHIKKEHPVI
1160 1170 1180 1190 1200
RHNEDLSMYL QKYSCSWDEW NNESKKSKNN IVKEVFGKQL RLINMCGPDA
1210 1220 1230 1240 1250
TELILSLWPT PTKLSAALNK YTHDGILAEK MKRIYLKNHD MIGKKRIKSP
1260 1270
IDVQLIAQLR QLYAPDSIER W
Length:1,271
Mass (Da):150,049
Last modified:September 22, 2009 - v2
Checksum:iBC85E470EA760A01
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014187 Genomic DNA. Translation: AAN37083.2.
LN999946 Genomic DNA. Translation: CZU00189.1.
RefSeqiXP_001348644.2. XM_001348608.2.

Genome annotation databases

EnsemblProtistsiCZU00189; CZU00189; PF3D7_1449400.
GeneDBiPF3D7_1449400.1:pep.
GeneIDi812052.
KEGGipfa:PF14_0470.

Similar proteinsi

Entry informationi

Entry nameiQ8IKY1_PLAF7
AccessioniPrimary (citable) accession number: Q8IKY1
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: September 22, 2009
Last modified: December 20, 2017
This is version 97 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported