Q8IKK7 (Q8IKK7_PLAF7) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Glyceraldehyde-3-phosphate dehydrogenase EMBL AAN37211.1
EC=1.2.1.12 EMBL AAN37211.1

Gene names

Name:	GAPDH EMBL AAN37211.1
ORF Names:	PF14_0598 EMBL AAN37211.1

Organism

Plasmodium falciparum (isolate 3D7)

Taxonomic identifier

36329 [NCBI]

Taxonomic lineage

Eukaryota › Alveolata › Apicomplexa › Aconoidasida › Haemosporida › Plasmodium › Plasmodium (Laverania)

Protein attributes

Sequence length	337 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. RuleBase RU000397

Ontologies

Keywords
Molecular function	Oxidoreductase RuleBase RU004274 EMBL AAN37211.1
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	gluconeogenesis Traceable author statement. Source: GeneDB_Pfalciparum
Molecular function	NAD binding Inferred from electronic annotation. Source: InterPro NADP binding Inferred from electronic annotation. Source: InterPro glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8IKK7 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: C678D13F328F2BA9	FASTA	337	36,635
	10 20 30 40 50 60 MAVTKLGING FGRIGRLVFR AAFGRKDIEV VAINDPFMDL NHLCYLLKYD SVHGQFPCEV 70 80 90 100 110 120 THADGFLLIG EKKVSVFAEK DPSQIPWGKC QVDVVCESTG VFLTKELASS HLKGGAKKVI 130 140 150 160 170 180 MSAPPKDDTP IYVMGINHHQ YDTKQLIVSN ASCTTNCLAP LAKVINDRFG IVEGLMTTVH 190 200 210 220 230 240 ASTANQLVVD GPSKGGKDWR AGRCALSNII PASTGAAKAV GKVLPELNGK LTGVAFRVPI 250 260 270 280 290 300 GTVSVVDLVC RLQKPAKYEE VALEIKKAAE GPLKGILGYT EDEVVSQDFV HDNRSSIFDM 310 320 330 KAGLALNDNF FKLVSWYDNE WGYSNRVLDL AVHITNN

References

[1]

"Genome sequence of the human malaria parasite Plasmodium falciparum." Gardner M.J., Hall N., Fung E., White O., Berriman M., Hyman R.W., Carlton J.M., Pain A., Nelson K.E., Bowman S., Paulsen I.T., James K.D., Eisen J.A., Rutherford K.M., Salzberg S.L., Craig A., Kyes S., Chan M.-S. , Nene V., Shallom S.J., Suh B., Peterson J., Angiuoli S., Pertea M., Allen J., Selengut J., Haft D., Mather M.W., Vaidya A.B., Martin D.M.A., Fairlamb A.H., Fraunholz M.J., Roos D.S., Ralph S.A., McFadden G.I., Cummings L.M., Subramanian G.M., Mungall C., Venter J.C., Carucci D.J., Hoffman S.L., Newbold C., Davis R.W., Fraser C.M., Barrell B.G. Nature 419:498-511(2002) [PubMed: 12368864] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Isolate 3D7.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE014187 Genomic DNA. Translation: AAN37211.1.
RefSeq	XP_001348772.1. XM_001348736.2.
3D structure databases
ProteinModelPortal	Q8IKK7.
SMR	Q8IKK7. Positions 1-337.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q8IKK7. 10 interactions.
MINT	MINT-1545556.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblProtists	PF14_0598:mRNA; PF14_0598:pep; PF14_0598.
GeneID	812180.
GenomeReviews	Gene locus GAPDH in contig AE014187_GR.
KEGG	pfa:PF14_0598.
NMPDR	fig|36329.1.peg.2474.
Organism-specific databases
EuPathDB	EupathDB:PF14_0598.
Phylogenomic databases
GeneTree	EPrGT00050000005860.
HOGENOM	HBG571736.
OMA	CESTGVF.
ProtClustDB	PTZ00023.
Enzyme and pathway databases
BRENDA	1.2.1.12. 1455.
Family and domain databases
InterPro	IPR020831. GlycerAld/Erythrose_P_DH. IPR020830. GlycerAld_3-P_DH_AS. IPR020829. GlycerAld_3-P_DH_cat. IPR020828. GlycerAld_3-P_DH_NAD(P)-bd. IPR006424. Glyceraldehyde-3-P_DH_1. IPR016040. NAD(P)-bd_dom. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KO	K00134.
PANTHER	PTHR10836. GAP_DH. 1 hit.
Pfam	PF02800. Gp_dh_C. 1 hit. PF00044. Gp_dh_N. 1 hit. [Graphical view]
PIRSF	PIRSF000149. GAP_DH. 1 hit.
PRINTS	PR00078. G3PDHDRGNASE.
SMART	SM00846. Gp_dh_N. 1 hit. [Graphical view]
TIGRFAMs	TIGR01534. GAPDH-I. 1 hit.
PROSITE	PS00071. GAPDH. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q8IKK7_PLAF7

Accession

Primary (citable) accession number: Q8IKK7

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2003
Last sequence update:	March 1, 2003
Last modified:	December 14, 2011
This is version 73 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)