ID   Q8IJA6_PLAF7            Unreviewed;      1697 AA.
AC   Q8IJA6;
DT   01-MAR-2003, integrated into UniProtKB/TrEMBL.
DT   01-MAR-2003, sequence version 1.
DT   27-MAR-2024, entry version 100.
DE   RecName: Full=Origin recognition complex subunit 3 N-terminal domain-containing protein {ECO:0000259|Pfam:PF07034};
GN   ORFNames=PF3D7_1029900 {ECO:0000313|EMBL:CZT98555.1};
OS   Plasmodium falciparum (isolate 3D7).
OC   Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC   Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX   NCBI_TaxID=36329 {ECO:0000313|EMBL:CZT98555.1, ECO:0000313|Proteomes:UP000001450};
RN   [1] {ECO:0000313|EMBL:CZT98555.1, ECO:0000313|Proteomes:UP000001450}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Isolate 3D7 {ECO:0000313|Proteomes:UP000001450};
RX   PubMed=12368864; DOI=10.1038/nature01097;
RA   Gardner M.J., Hall N., Fung E., White O., Berriman M., Hyman R.W.,
RA   Carlton J.M., Pain A., Nelson K.E., Bowman S., Paulsen I.T., James K.,
RA   Eisen J.A., Rutherford K., Salzberg S.L., Craig A., Kyes S., Chan M.S.,
RA   Nene V., Shallom S.J., Suh B., Peterson J., Angiuoli S., Pertea M.,
RA   Allen J., Selengut J., Haft D., Mather M.W., Vaidya A.B., Martin D.M.,
RA   Fairlamb A.H., Fraunholz M.J., Roos D.S., Ralph S.A., McFadden G.I.,
RA   Cummings L.M., Subramanian G.M., Mungall C., Venter J.C., Carucci D.J.,
RA   Hoffman S.L., Newbold C., Davis R.W., Fraser C.M., Barrell B.;
RT   "Genome sequence of the human malaria parasite Plasmodium falciparum.";
RL   Nature 419:498-511(2002).
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DR   EMBL; LN999944; CZT98555.1; -; Genomic_DNA.
DR   RefSeq; XP_001347576.1; XM_001347540.1.
DR   AlphaFoldDB; Q8IJA6; -.
DR   IntAct; Q8IJA6; 5.
DR   STRING; 36329.Q8IJA6; -.
DR   PaxDb; 5833-PF10_0292; -.
DR   EnsemblProtists; CZT98555; CZT98555; PF3D7_1029900.
DR   GeneID; 810449; -.
DR   KEGG; pfa:PF3D7_1029900; -.
DR   VEuPathDB; PlasmoDB:PF3D7_1029900; -.
DR   HOGENOM; CLU_252739_0_0_1; -.
DR   InParanoid; Q8IJA6; -.
DR   OMA; FVRSNQK; -.
DR   OrthoDB; 247981at2759; -.
DR   PhylomeDB; Q8IJA6; -.
DR   Proteomes; UP000001450; Chromosome 10.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   InterPro; IPR045667; ORC3_N.
DR   PANTHER; PTHR31765:SF3; ORC3_N DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR31765; PROTEIN CBG12783; 1.
DR   Pfam; PF07034; ORC3_N; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000001450}.
FT   DOMAIN          403..690
FT                   /note="Origin recognition complex subunit 3 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF07034"
FT   REGION          248..311
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1200..1278
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1520..1550
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1626..1645
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        268..288
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        291..311
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1203..1278
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1520..1544
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1697 AA;  201369 MW;  3AE8996CC0615396 CRC64;
     MNEKKNTIFK GKGYILKGVN KEFIDDRKKR DLFIDKKKKN IFNRFNPFTL PLLGKNKLCE
     VDEKCDMKKS KSSDKYKEAN ININVLNEGE FNSYLLRNRA FRLTWTSIIE KIKHEIDIEI
     YKNLNDVFEE IYLYSISNNE YLPLILITAG TNVADHEIII DALSYELKIW NNNNNKKKKQ
     HTHTNTRTQK GCMDQSGNLF DYVHGEGKDY IYEKIKRDMN KGDTNQGDHL YDKININKVN
     LILPGNEDSA HALMNPSHES NNQDKEIKMK KKKKKKKKKK KRKKRRIFNG NICNKDSSIS
     PNSSYHNHFN NDDDNYNVNN LLNEDSYDDN DDVYVCSLNS NTSNNINSAV YNIYTQLYRD
     YKMRYFLKKY KKKDGRNNYN NGVKNAYISN ETRKRTRNYS NSSNSYNLNR DDIDNDCDNT
     CDVSNHNSFV RLSFLNKEFR EDNKVINKNM VNIDRLIDLY KKMSELNMKN ISEEEIEGLS
     KKRVFTNKYN SDNIYNMDEM YNVMNSKDVM FTSPKGGYKN NKGSGIYKDM NESNNSFIKE
     YGPLELYNKQ NNYFYDGRKK VRIIILIHDC EYFNINILNG ILNILINLRI DNKICLSVIL
     GVSTPSFFFN RITTPDTQSK LRIKTVDILN NKLMCDRICN ILLFENLLPF ILNFKTVHAI
     KLLLHKNNQS ISHLIHILYI LTKEFYDNNI LSFLCIPMNY YLNICTNDDE EKEKMDSNYS
     AYTYVRSYQA NLSNFFKYDI RKVHQKIISL CYSSNLYYRH LSYIKKKYST ILIKNYFQLH
     GPDSVVHTPR HSDDEPEFFN LKSKKVDHMK QERNIQVVDK ELSSVNNDKI NENNINGDIH
     GDIHGDIHGD IHGDIHGDIH GDIHGDIHGD IHGDIHGDIH SRNNKKSPFD RASYAWEFKT
     KTINWWYDHP FKDLIYLYEN GRVRTNNKEE IIDKLLNDEE NKKEIINNMH SHINGNNNLY
     DIENVKEINK NLCSFTLPLN VLQLIERKYA FNIAINLINI IIKTKSEYTT SIKRSEYFRN
     LFQNYEKIKW NENKNILYIE ELYNIVEKDV KKCINFLIDM MTPYYFKNHQ VLLNVFKEFK
     EYYTNIYPIV YNLEDYLYLL KDKEYKKHQE LFINDDFSKT CTYSISYSIY FSLLSRLDDM
     LEMLRNVIRM EEKQKKKTNQ CTAFDDNAGY IKKNICVNNL SRKREEHVED SGCVLNVSSY
     KQQNEKKENE KKENEKKENE KKENEKKENE KKENEKKENE KKENEKKENE KKENEKKENE
     KKENEKKENE KKENDKRFFI QADDHLNEDE DEEAEQQHNI QYNNSVNYND PYYCAHDIGT
     SNKTKYFPSN NIINIHEIDN KKKRFKRYLT IENKSLKKKK NDEHNINAED ISNCINLFIH
     DYIYLLLLPP ISYHPLAYEL ILHKPDKDFT NIMTRDIKKE LLTTLCYTNP YKTGNLMCSS
     CCLFKDNPYN SNPENNIITN NKIYLNPTYD NISTLEDMVN LYRVYEKCNK TIDLYNLFIL
     YLNIKVDKYW AYSINDKNKN NNNNNNNNNN NNNNNNNKNN NNNNSDWGDK EDIKSPHLCK
     MKNTPTENLA NDILQEYYLK FIITINTFCS FLKILKPPNV SALLNYNDKN GNNDDYYEDD
     EYYHTNNNTN NLGRGAKKKS SDDNNSSQES IIQFLKEIKK SLQGCTSKKL LFGKLYYNHI
     IASREYFLQN LMEKNNE
//