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Protein
Submitted name:

DNA polymerase zeta catalytic subunit, putative

Gene

PF10_0362

Organism
Plasmodium falciparum (isolate 3D7)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  • DNA binding Source: InterPro
  • DNA-directed DNA polymerase activity Source: GeneDB
  • nucleotide binding Source: InterPro

GO - Biological processi

  • DNA replication Source: GeneDB
  • error-prone translesion synthesis Source: GO_Central

Names & Taxonomyi

Protein namesi
Submitted name:
DNA polymerase zeta catalytic subunit, putativeImported
Gene namesi
ORF Names:PF10_0362Imported
OrganismiPlasmodium falciparum (isolate 3D7)Imported
Taxonomic identifieri36329 [NCBI]
Taxonomic lineageiEukaryotaAlveolataApicomplexaAconoidasidaHaemosporidaPlasmodiidaePlasmodiumPlasmodium (Laverania)
Proteomesi
  • UP000001450 Componenti: Chromosome 10

Organism-specific databases

EuPathDBiPlasmoDB:PF3D7_1037000.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei68 – 88HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • nucleus Source: GO_Central
  • zeta DNA polymerase complex Source: GeneDB

Keywords - Cellular componenti

Membrane

Structurei

3D structure databases

ProteinModelPortaliQ8IJ38.
SMRiQ8IJ38.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1037 – 1146DNA_pol_BInterPro annotationAdd BLAST110
Domaini1319 – 1530DNA_pol_BInterPro annotationAdd BLAST212

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili466 – 536Sequence analysisAdd BLAST71
Coiled coili626 – 646Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

HOGENOMiHOG000284524.
InParanoidiQ8IJ38.
KOiK02350.
OMAiAFNICYS.

Family and domain databases

Gene3Di3.30.420.10. 1 hit.
3.90.1600.10. 1 hit.
InterProiView protein in InterPro
IPR006172. DNA-dir_DNA_pol_B.
IPR017964. DNA-dir_DNA_pol_B_CS.
IPR006134. DNA-dir_DNA_pol_B_multi_dom.
IPR023211. DNA_pol_palm_dom_sf.
IPR030559. PolZ_Rev3.
IPR012337. RNaseH-like_sf.
IPR036397. RNaseH_sf.
PANTHERiPTHR10322:SF5. PTHR10322:SF5. 2 hits.
PfamiView protein in Pfam
PF00136. DNA_pol_B. 2 hits.
SMARTiView protein in SMART
SM00486. POLBc. 1 hit.
SUPFAMiSSF53098. SSF53098. 6 hits.
PROSITEiView protein in PROSITE
PS00116. DNA_POLYMERASE_B. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8IJ38-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNLAEKPKAF FICKFLFFYY IYKKPILPFD SLKCKISGKE IPYVCIIQIL
60 70 80 90 100
GLSLLGQRVC LYIHDLMYVY LIVYFILFYC FISFYFIFFH SPISDDKLEI
110 120 130 140 150
ELCSFLEEEY GKARKDPSNN VCVYNIERVK RKGIYGYNEE CDDFLKISFL
160 170 180 190 200
YPNTINYFAS LLKKKLFKKR IWDLYEVHIN YMLHFLCMKN IYGCSEIYID
210 220 230 240 250
KNIYFRKEFV NEINFECIEK EERWYLGEKK YNLDNFKRNK YLEVDAPLVF
260 270 280 290 300
TIKTINVNFS SLKRETTYDI ECDIKHQHIL NEKIYTYEFE KNKIKWKKEF
310 320 330 340 350
NFDLPINHLD SFAKMWMKEK KRCKYMDMDL KRELFYFKSY ENDLCFDTFD
360 370 380 390 400
VLTERTKKMF QGFLEFMKRM QSEKDKVNYE QILEYDNIEN VKKYNKVIND
410 420 430 440 450
DMKLKEDHNF NSDMNNIEVN IKQINNNDNI NNCKNVVDNE EENDMLSNMI
460 470 480 490 500
SNKKKDHMGI SPNLFIQNKE QEKEKQDERE KEKQDEREKE KQDEREKEKQ
510 520 530 540 550
DEREKEKQEE REKEKQEERE KEKQEEREKE KQEERECFIE YVNEKGCIAS
560 570 580 590 600
FEINKKRKDV VRYSFKKEPP RINKCYAVIN NLVDHISGRD NKNMKEKMKG
610 620 630 640 650
NIYNRIHDNI EDENKEDTSK FEYIGKENHM ENKENIRKQY EQIKSDNMKK
660 670 680 690 700
KINIKYGNIF FLEILTEIKD ENCYSSDYNQ DKIKAVFYIV REERLMNLYE
710 720 730 740 750
DYNNCMGIIA TKPFPNISYL FNESEDMNNL KGTNEVKLNE SKLNESKLNE
760 770 780 790 800
SKLNEEELKL CKDMYHIEDV NLCTNNCRSI EKNRDNLIND KNVINKKNDD
810 820 830 840 850
TYGSSKELCC SKNGYHTNKI IKEITNNDIK KVKRTFFDFN INYNNVNICI
860 870 880 890 900
VENERELIQK LINKILFYSP LSIVSYENDK YNINYINQRC LALDIGNFYK
910 920 930 940 950
MICKLNDQKK FLDLHNAYSR NIKGIIIESL YKLSNTYNTS FENLCKHYLN
960 970 980 990 1000
INIPSINKYT LYYWYNYNTK RKIKANGSST VVNKDIINND LWNDMDEEHI
1010 1020 1030 1040 1050
YFPYRHITIK HYLRKVYFIL LIYDKICFLK RKMNFCKYIH VDLLSLINRG
1060 1070 1080 1090 1100
SQYIIESFLL KMSIKYNYVL YSPSNKEIFD QRPILHTPLI LQPKSSINFF
1110 1120 1130 1140 1150
PLLVFDFQSL YPSILIAFNI CYSTCLGTIT LKRKLNQMDE EKNNEKKDEN
1160 1170 1180 1190 1200
IEGSLMEKCE TYKNGINDKN HIYDKNELSC SNKNDLPSDE YTDMMNISED
1210 1220 1230 1240 1250
AKYLIDLLDE NINDCISSAD PMIEPDIIQS NGKGLGENIP SENMITEDHD
1260 1270 1280 1290 1300
KIKYKLDMNN KLEMGNIKHV NIMNEQSIYG NINKNKLYSN EEKSLESNFE
1310 1320 1330 1340 1350
FIKLGVMKNV PSISSRIKNL KSEDIIITSN NTIYVKKHKR KGICPLFLED
1360 1370 1380 1390 1400
ILKTRIMLKR CMGMYEERVN KKLNERMGKL KLILNVATGY IGANFSGRMP
1410 1420 1430 1440 1450
CVDISESIIS IGRNFLLFII EYIKENYKFV KILYGDTDSL FLLNETTDDI
1460 1470 1480 1490 1500
QSSFKLAYEI LNSINNILPL PMYLNFEKIY CPSLLLTKKR YFGFSFKNEN
1510 1520 1530 1540 1550
QDNPILDLKG VESIRSDQCI LVKNILIQIY FILFYFKNNC YFSYCCCCCY
1560 1570 1580 1590 1600
LCKNFFSNLI CSCKELNVHK TDPCFLFTLL KIVLSICKVR RYINQNEDKY
1610 1620 1630 1640 1650
NINNNNNNNN KSNCHHNKQN GNKINDISNL SLELYRKVPS FDKVKLYKEV
1660 1670 1680 1690 1700
MNWVEYYDNE NLLLKTLNFL YREKYSFLIY LFNLFDEATL HKEIEKIIQT
1710 1720 1730 1740 1750
NFEKIQNQKN NKCCFINPSN VFKSCLCVKN INENIKCDQI RCYCNVKQAM
1760 1770 1780 1790 1800
FFFYNPTYNK VDYVFNTKLF YSHLLSHIRQ TLSEYFNKIY DNQISCDNFI
1810 1820 1830 1840 1850
IYRKVKLGTY KGEMQGIRRK VSLPPQAIVA RKIMRDFPNS IITYKEKVPY
1860 1870 1880 1890 1900
IFTKKLKDDK IYSSVSHPHF IRGIYRSFRF DCGSTEQLEI SEDNCNNDSE
1910 1920 1930 1940 1950
KNGDIEKNDN IEKNDNIEKI GDIEKIGDIK KIGDIEKNEN IEKNENIEKN
1960 1970 1980 1990 2000
DNIEKNDNIE KTDNIENFPS SEKSEYCDIS ENEEKSENFK NSDMSEYCEY
2010 2020 2030 2040 2050
DKNELLYVDG MMEIEELKNR ILGINIKKKM KKKKKKIKEI NYDYYIQNLI
2060 2070 2080 2090 2100
IPPLKRMLDL LPFCSLNLDE IFYRTKRKFN WNKAKLEMFS KYYKNMDNKL
2110 2120 2130 2140 2150
LKNNNVTNKG INLMNILNED KINNKEQNGN TKKKLNFLHN VNRTMETYKD
2160 2170 2180 2190 2200
MNNKSKIIIR LEEQGENEEL KVTNKIMNSY VEINKSQNML KKLNKICLMC
2210 2220 2230 2240
ANSEMEALAC NYSVHCKIFF KRINLQENIL KNKDSINRLS
Length:2,240
Mass (Da):267,715
Last modified:March 1, 2003 - v1
Checksum:i63B913D755074DF6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014834 Genomic DNA. Translation: AAN35559.1.
RefSeqiXP_001347646.1. XM_001347610.1.

Genome annotation databases

GeneDBiPF3D7_1037000.1:pep.
GeneIDi810519.
KEGGipfa:PF10_0362.

Similar proteinsi

Entry informationi

Entry nameiQ8IJ38_PLAF7
AccessioniPrimary (citable) accession number: Q8IJ38
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: December 20, 2017
This is version 104 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported