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Protein
Submitted name:

DNA repair helicase rad25, Putative

Gene

PF10_0369

Organism
Plasmodium falciparum (isolate 3D7)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  • ATP binding Source: InterPro
  • ATP-dependent DNA helicase activity Source: InterPro
  • damaged DNA binding Source: GeneDB
  • DNA binding Source: GeneDB
  • helicase activity Source: GeneDB

GO - Biological processi

Keywordsi

Molecular functionHelicaseImported, Hydrolase
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-PFA-6781823. Formation of TC-NER Pre-Incision Complex.
R-PFA-72086. mRNA Capping.
R-PFA-73776. RNA Polymerase II Promoter Escape.
R-PFA-77075. RNA Pol II CTD phosphorylation and interaction with CE.

Names & Taxonomyi

Protein namesi
Submitted name:
DNA repair helicase rad25, PutativeImported (EC:3.6.3.-Imported)
Gene namesi
ORF Names:PF10_0369Imported, PF3D7_1037600Imported
OrganismiPlasmodium falciparum (isolate 3D7)Imported
Taxonomic identifieri36329 [NCBI]
Taxonomic lineageiEukaryotaAlveolataApicomplexaAconoidasidaHaemosporidaPlasmodiidaePlasmodiumPlasmodium (Laverania)
Proteomesi
  • UP000001450 Componenti: Chromosome 10

Organism-specific databases

EuPathDBiPlasmoDB:PF3D7_1037600.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini398 – 562Helicase ATP-bindingInterPro annotationAdd BLAST165
Domaini616 – 786Helicase C-terminalInterPro annotationAdd BLAST171

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili308 – 328Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

HOGENOMiHOG000160172.
InParanoidiQ8IJ31.
KOiK10843.
OMAiTKHVHPL.

Family and domain databases

CDDicd00079. HELICc. 1 hit.
InterProiView protein in InterPro
IPR032438. ERCC3_RAD25_C.
IPR006935. Helicase/UvrB_N.
IPR014001. Helicase_ATP-bd.
IPR001650. Helicase_C.
IPR027417. P-loop_NTPase.
IPR001161. XPB/Ssl2.
IPR032830. XPB/Ssl2_N.
PfamiView protein in Pfam
PF16203. ERCC3_RAD25_C. 1 hit.
PF13625. Helicase_C_3. 1 hit.
PF04851. ResIII. 1 hit.
SMARTiView protein in SMART
SM00487. DEXDc. 1 hit.
SM00490. HELICc. 1 hit.
SUPFAMiSSF52540. SSF52540. 3 hits.
TIGRFAMsiTIGR00603. rad25. 1 hit.
PROSITEiView protein in PROSITE
PS51192. HELICASE_ATP_BIND_1. 1 hit.
PS51194. HELICASE_CTER. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8IJ31-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMNSLKDSSN YSPNLSHTRG SRKRSDIFNE NYYAKNLKRR KLKAAKKLKD
60 70 80 90 100
STNGEFTKKV KKQLKDYYEM RFDKKVINLP FSTDSINIQQ RGFHDYSKDM
110 120 130 140 150
KLKKNHMNKP LWICSDGFIY LEMFNSCSKQ ASDFLITIAE PICRPELIHE
160 170 180 190 200
FQLTIFSLYA AISVGITLDE LLINLDKFSK NVLPNELISN ITKSAESFGK
210 220 230 240 250
VKLVLRENKY YIEATNKSEL DYLLNNDTIQ NARIYSTDNN NDKNMISLYN
260 270 280 290 300
LNNRHRDNNK NDNKNNNDDN NNIDKTTSNL LNEDQKGKDC YVTYEAPVLD
310 320 330 340 350
TTQLGFKISE SEKQLMMEEK KHANLNANEN STNSAEVYSF EVNCDKIEEV
360 370 380 390 400
KQEALQTMQR PLLMEYDFRR DKKNPNLICS LKSHVQIRYY QEKALRKMFS
410 420 430 440 450
NGRSRSGIIV LPCGVGKTLT GITAASTIKK SALFLTTSAV AVEQWKKQFE
460 470 480 490 500
DFTNIHPRHI RILTSDYKLD LWPINEAGVL ISTYTMLSYS GKRSEQSLRI
510 520 530 540 550
VNDIRRREWG LLVFDEVQFA PAPSFRRIND IVKSHCKLGL TATLVREDLL
560 570 580 590 600
IRDLHWIIGP KLYEANWVEL QNKGFLAKAL CKEIWCSMPC SFYKYYLKSN
610 620 630 640 650
SFIKRRLYTC NPRKLMMCEY LIKYHEQNND KIIVFSDNIF ALLHIAKTLN
660 670 680 690 700
KPFIYGKLSP IERIAIINKF KHDSSINTIL LSKVGDNAID IPIANVVIQI
710 720 730 740 750
SFNFASRRQE AQRLGRIIRP KNKANEKKNI NDPDSFFYSL VSKDTIEMCY
760 770 780 790 800
SDKRQRFLIN QGYAYNVLSD NIVDFNKLNL VYKNKKIQEN LLKCILASTD
810 820 830 840 850
DGNMDEDDDL FEDQSFKKDN TKVNKTNSNI LLNKKEDSLK KIDNTTGGLL
860 870 880
KLSSNMDVTF ADKKKIPTKK FADKHILFRK FLSQNK
Length:886
Mass (Da):102,876
Last modified:March 1, 2003 - v1
Checksum:i8BC9F389EEAE324E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014185 Genomic DNA. Translation: AAN35566.1.
LN999944 Genomic DNA. Translation: CZT98632.1.
RefSeqiXP_001347653.1. XM_001347617.1.

Genome annotation databases

EnsemblProtistsiCZT98632; CZT98632; PF3D7_1037600.
GeneDBiPF3D7_1037600.1:pep.
GeneIDi810526.
KEGGipfa:PF10_0369.

Similar proteinsi

Entry informationi

Entry nameiQ8IJ31_PLAF7
AccessioniPrimary (citable) accession number: Q8IJ31
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: December 20, 2017
This is version 101 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported