Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Chromatin remodeling protein

Gene

PF11_0053

Organism
Plasmodium falciparum (isolate 3D7)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

  • ATP binding Source: GeneDB
  • ATP-dependent helicase activity Source: GeneDB
  • DNA binding Source: InterPro
  • DNA-dependent ATPase activity Source: GeneDB

GO - Biological processi

  • ATP-dependent chromatin remodeling Source: InterPro
  • chromatin remodeling Source: GeneDB
  • covalent chromatin modification Source: UniProtKB-KW
  • regulation of transcription, DNA-templated Source: GeneDB

Keywordsi

Molecular functionChromatin regulatorUniRule annotation, HelicaseUniRule annotation, Hydrolase
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Chromatin remodeling proteinImported
Submitted name:
PfSNF2LImported
Gene namesi
ORF Names:PF11_0053Imported, PF3D7_1104200Imported
OrganismiPlasmodium falciparum (isolate 3D7)Imported
Taxonomic identifieri36329 [NCBI]
Taxonomic lineageiEukaryotaAlveolataApicomplexaAconoidasidaHaemosporidaPlasmodiidaePlasmodiumPlasmodium (Laverania)
Proteomesi
  • UP000001450 Componenti: Chromosome 11

Organism-specific databases

EuPathDBiPlasmoDB:PF3D7_1104200.

Subcellular locationi

  • Nucleus UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

NucleusUniRule annotation

Interactioni

Protein-protein interaction databases

IntActiQ8IIW0. 7 interactors.
MINTiMINT-1585538.

Structurei

3D structure databases

SMRiQ8IIW0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini334 – 498Helicase ATP-bindingInterPro annotationAdd BLAST165
Domaini630 – 781Helicase C-terminalInterPro annotationAdd BLAST152

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili125 – 145Sequence analysisAdd BLAST21
Coiled coili219 – 239Sequence analysisAdd BLAST21
Coiled coili822 – 842Sequence analysisAdd BLAST21
Coiled coili900 – 920Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the SNF2/RAD54 helicase family. ISWI subfamily.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

HOGENOMiHOG000282197.
InParanoidiQ8IIW0.
OMAiDNSEEFD.

Family and domain databases

CDDicd00079. HELICc. 1 hit.
InterProiView protein in InterPro
IPR014001. Helicase_ATP-bd.
IPR001650. Helicase_C.
IPR009057. Homeobox-like_sf.
IPR029915. ISWI.
IPR027417. P-loop_NTPase.
IPR000330. SNF2_N.
PANTHERiPTHR10799:SF887. PTHR10799:SF887. 2 hits.
PfamiView protein in Pfam
PF00271. Helicase_C. 1 hit.
PF00176. SNF2_N. 1 hit.
SMARTiView protein in SMART
SM00487. DEXDc. 1 hit.
SM00490. HELICc. 1 hit.
SUPFAMiSSF46689. SSF46689. 1 hit.
SSF52540. SSF52540. 2 hits.
PROSITEiView protein in PROSITE
PS51192. HELICASE_ATP_BIND_1. 1 hit.
PS51194. HELICASE_CTER. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8IIW0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFRNVRDYFK SSNDVNEEKK NDVGSVHMDE NTENYDKESN GFVHRDFNNG
60 70 80 90 100
INKEDKDYEE LDLKKLNVSS NDITKEGNNM NENMMNRKLN SSVEDGNDNN
110 120 130 140 150
HDKNVHRNIG NDTHVSYDDK RKSYLDNNEE NSEQMNDNMK KRKLNEISYD
160 170 180 190 200
NNEEDEFRNK KDDSMEMNDK EKGSTNMSTI NDNNNNHNDD SNNHNDDSNN
210 220 230 240 250
HNDDSNNHND DSNNHNDDNN NHNEDNNNHN DDNNNHNDDN NYNSEEKPNY
260 270 280 290 300
LQEKLEQLLA QTKRYTEKLA GQRLKMNAQM KSSKKGRCLL TEKEEDFMLL
310 320 330 340 350
KDANEEDEAI ILKQPMNING TMKPYQLEGL NWLYQLYRFK INGILADEMG
360 370 380 390 400
LGKTLQTISL LCYLRFNKNI KKKSIIICPR STLDNWYEEI KKWCTPMKAF
410 420 430 440 450
KYYGNKDQRK ELNRNLLHSD FDVLLTTYEI VIKDKSALYD IDWFFLVIDE
460 470 480 490 500
AHRIKNEKSV LSSSVRFLRS ENRLLITGTP LHNNLKELWS LLNFLMPKIF
510 520 530 540 550
DNSEEFDNLF NISKISTNDN KQSEIITQLH TILKPFMLRR LKVEVEQSLP
560 570 580 590 600
PKREIYIFVG MSKLQKKLYS DILSKNIDVL NAMTGSKNQM LNILMQLRKC
610 620 630 640 650
CNHPYLFDGI EEPPYIEGNH LIETSGKMSL LDKLLPRLKK ENSRVLLFSQ
660 670 680 690 700
MTRLLDIIDD YCRWKNYPYL RIDGSTPGDE RQVRINQFNE PNSKYFIFLL
710 720 730 740 750
STRAGGIGIN LTTADIVILF DSDYNPQMDI QAMDRAHRIG QKKRVIVYRF
760 770 780 790 800
VTQNSVEEKI VERAAKKLKL DSLIIQKGKL NLNSAKENNK QELHDILNFG
810 820 830 840 850
APEVYKTQDI SSISDEDIDI ILADAEKRTI EIEKKLKNLE NIFDLTNISL
860 870 880 890 900
DGGLNMYNDL EKEASEESTD EEDSSGSGEE TILEGSGNND IVEENGVKKK
910 920 930 940 950
KKKKKNINKI RRTIKKFLKN NKKNMTFLDL GERKSKWKVM NTACGRTNKK
960 970 980 990 1000
KMVLHGWRAE ARGGHDFQFF NVEKLDELEK IEDKWNNYMI NQEKINVLIE
1010 1020 1030 1040 1050
AQNEEKDYEK IVTFNEFLDK HAKNIYQIIT LINPSLFDEH KDTKEEELLK
1060 1070 1080 1090 1100
MGTHSDVNSN DKDYKRSSFM STDYNMKTTY LNNINSNNNN NNNNINDNVG
1110 1120 1130 1140 1150
TSINTIDDQQ YFKKKILSLF ESGKKLQMIK FKDRNIKNCY TQVANFIKKN
1160 1170 1180 1190 1200
FPEKINNNDT NNNKSTTLKN KKLKKGKQTK NVNVEKDIAS VDIEKIKLQK
1210 1220 1230 1240 1250
QELMKQGFAK WNKAEFNKLM SGLIIYGTNE VEYIYEKYFS NSKKSMEDIK
1260 1270 1280 1290 1300
AYLTVFFRKY DQIKGGVRLF DKIKRSDLQK KIIEEENDMI TEFVEKQLSE
1310 1320 1330 1340 1350
GVDSIEKLQL PSNLRYDFME KREVLNITEE VKTENEENVL SNEELAYYDR
1360 1370 1380 1390 1400
ENKILLWLLY QQGVVQIKNI HILTPYYWPE AYNFFKYATT PFENVEYRCR
1410 1420
LIVDAIAELY AKKENVPLNN KDKRRI
Length:1,426
Mass (Da):167,441
Last modified:March 1, 2003 - v1
Checksum:iF16DC0BE1E8862C6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014836 Genomic DNA. Translation: AAN35642.1.
LN999945 Genomic DNA. Translation: CZT98707.1.
RefSeqiXP_001347729.1. XM_001347693.1.

Genome annotation databases

EnsemblProtistsiCZT98707; CZT98707; PF3D7_1104200.
GeneDBiPF3D7_1104200.1:pep.
GeneIDi810605.
KEGGipfa:PF11_0053.

Similar proteinsi

Entry informationi

Entry nameiQ8IIW0_PLAF7
AccessioniPrimary (citable) accession number: Q8IIW0
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: December 20, 2017
This is version 104 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported