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Protein
Submitted name:

26S proteasome regulatory complex subunit, putative

Gene

PF11_0303

Organism
Plasmodium falciparum (isolate 3D7)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  • endopeptidase activity Source: GeneDB
  • enzyme regulator activity Source: InterPro

GO - Biological processi

  • proteasome-mediated ubiquitin-dependent protein catabolic process Source: GO_Central
  • proteolysis Source: GeneDB

Keywordsi

Molecular functionHydrolaseImported

Enzyme and pathway databases

ReactomeiR-PFA-1236978. Cross-presentation of soluble exogenous antigens (endosomes).
R-PFA-5687128. MAPK6/MAPK4 signaling.
R-PFA-5689603. UCH proteinases.
R-PFA-5689880. Ub-specific processing proteases.
R-PFA-6798695. Neutrophil degranulation.
R-PFA-68949. Orc1 removal from chromatin.
R-PFA-983168. Antigen processing: Ubiquitination & Proteasome degradation.

Names & Taxonomyi

Protein namesi
Submitted name:
26S proteasome regulatory complex subunit, putativeImported
Submitted name:
26S proteasome regulatory subunit RPN7,putativeImported (EC:3.4.25.1Imported)
Gene namesi
ORF Names:PF11_0303Imported, PF3D7_1129200Imported
OrganismiPlasmodium falciparum (isolate 3D7)Imported
Taxonomic identifieri36329 [NCBI]
Taxonomic lineageiEukaryotaAlveolataApicomplexaAconoidasidaHaemosporidaPlasmodiidaePlasmodiumPlasmodium (Laverania)
Proteomesi
  • UP000001450 Componenti: Chromosome 11

Organism-specific databases

EuPathDBiPlasmoDB:PF3D7_1129200.

Subcellular locationi

GO - Cellular componenti

  • proteasome complex Source: GeneDB

Keywords - Cellular componenti

ProteasomeImported

Interactioni

Protein-protein interaction databases

IntActiQ8II71. 2 interactors.
MINTiMINT-1646226.

Structurei

3D structure databases

SMRiQ8II71.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini294 – 377PINTInterPro annotationAdd BLAST84

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili74 – 105Sequence analysisAdd BLAST32

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

HOGENOMiHOG000214998.
InParanoidiQ8II71.
KOiK03037.
OMAiVDYIDQE.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiView protein in InterPro
IPR000717. PCI_dom.
IPR035268. PSMD6.
IPR019585. Rpn7/CSN1.
IPR036388. WH-like_DNA-bd_sf.
IPR036390. WH_DNA-bd_sf.
PANTHERiPTHR14145:SF1. PTHR14145:SF1. 1 hit.
PfamiView protein in Pfam
PF01399. PCI. 1 hit.
PF10602. RPN7. 1 hit.
SMARTiView protein in SMART
SM00088. PINT. 1 hit.
SUPFAMiSSF46785. SSF46785. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8II71-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEDNKEENCE LNKNSYPNFH LADLFYLLQL PNISINERND LLQSLFDEIK
60 70 80 90 100
KNHMYPYYNY ICQELNLNFD EEYFKSLKEK ADEELNQIEN KLSESAENFD
110 120 130 140 150
SLDNKNDVLL KANFFCKISD KENAFKEYEE TYKKGIGMGM KLDILLTMIR
160 170 180 190 200
ICIFYNDVKN LKKYLEQART QMEKGGDWER KNKLKIYEAL NYIMIRNFAE
210 220 230 240 250
ASKILIDAAS TFTATEIISY EKIIFYVVIL GIMTEERTVL DKKILNSSVI
260 270 280 290 300
LQITSSDEDL HTYLHSFYHC DYRTFMEKTI KIAMRVKRDR YLGRHYRYFI
310 320 330 340 350
RNTRVRAYKQ FLEPFKNVTL KNMAFAFGVS EEFIENEISS FIANGKLNCK
360 370 380 390
IDKVNGSIES NQPNERNTMY QNTIKKGDIL LNRIQKLSRV IDM
Length:393
Mass (Da):46,624
Last modified:September 22, 2009 - v2
Checksum:iC7D6BE78F3F9FEA8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014186 Genomic DNA. Translation: AAN35887.2.
LN999945 Genomic DNA. Translation: CZT98954.1.
RefSeqiXP_001347974.2. XM_001347938.2.

Genome annotation databases

EnsemblProtistsiCZT98954; CZT98954; PF3D7_1129200.
GeneDBiPF3D7_1129200.1:pep.
GeneIDi810850.
KEGGipfa:PF11_0303.

Similar proteinsi

Entry informationi

Entry nameiQ8II71_PLAF7
AccessioniPrimary (citable) accession number: Q8II71
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: September 22, 2009
Last modified: October 25, 2017
This is version 100 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported