Q8IHG0 (Q8IHG0_DROME) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
AT04516p EMBL AAN71025.1

Gene names

Name:	Drp1 FlyBase FBgn0026479
Synonyms:	noodle FlyBase FBgn0031438
ORF Names:	CG3210 EMBL AAN71025.1 FlyBase FBgn0031438

Organism

Drosophila melanogaster (Fruit fly)

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	735 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the dynamin family. RuleBase RU003932 Contains 1 GED domain. SAAS SAAS001401

Ontologies

Keywords
Ligand	GTP-binding SAAS SAAS019762 RuleBase RU003932 Nucleotide-binding
Gene Ontology (GO)
Biological process	cytokinesis Inferred from mutant phenotype. Source: FlyBase mitochondrion localization Inferred from mutant phenotype. Source: FlyBase sperm mitochondrion organization Inferred from mutant phenotype. Source: FlyBase synaptic vesicle budding from presynaptic membrane Non-traceable author statement. Source: FlyBase
Cellular component	microtubule associated complex Inferred from direct assay. Source: FlyBase
Molecular function	GTP binding Inferred from electronic annotation. Source: UniProtKB-KW GTPase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8IHG0 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: A040E702D7DBFF66	FASTA	735	82,539
	10 20 30 40 50 60 MEALIPVINK LQDVFNTVGS DSIQLPQIVV LGSQSSGKSS VIESVVGRSF LPRGTGIVTR 70 80 90 100 110 120 RPLVLQLIYS PLDDRENRSA ENGTSNAEEW GRFLHTKKCF TDFDEIRKEI ENETERAAGS 130 140 150 160 170 180 NKGICPEPIN LKIFSTHVVN LTLVDLPGIT KVPVGDQPED IEAQIKELVL KYIENPNSII 190 200 210 220 230 240 LAVTAANTDM ATSEALKLAK DVDPDGRRTL AVVTKLDLMD AGTDAIDILC GRVIPVKLGI 250 260 270 280 290 300 IGVMNRSQKD IMDQKHIDDQ MKDEAAFLQR KYPTLATRNG TPYLAKTLNR LLMHHIRDCL 310 320 330 340 350 360 PDLKTRVNIM ATQFQSLLNS YGEDVSDKSQ TLLQIITKFS SAYCCTIEGT ARNIETTELC 370 380 390 400 410 420 GGARMGYIFH ETFGRTLDSI HPLAGLSKMD ILTAIRNATG PRPALFVPEV SFELLVKRQI 430 440 450 460 470 480 RRLEEPSLRC VELIHEEMQR IVQHCGNEVQ QEMLRFPKLH EKIVDVVTQL LRRRLPHTNV 490 500 510 520 530 540 MVENIVAIEL AYINTKHPDF HKDAALVPSL LKTDSDPYSQ INLGQRRANT PRNHMSPQIS 550 560 570 580 590 600 SHSAGSQQPQ QQQPPQPSSS QQQYSQVHEQ NHVAENSTPS MASTWLSNIL PPAPTRPDSI 610 620 630 640 650 660 ENSTNNTPVH NNIVSPVKPV NLLPDVPANH NPRRLTDKEQ KDCDVIEHLI KSYFYIVRKS 670 680 690 700 710 720 IQDSVPKAIM HFLVNYVKDN LQSELVTHLY KSDKAETLLN ESDHIAVRRK EAADMLKALT 730 RANHIISEIR ETHMW

References

[1]

Stapleton M., Brokstein P., Hong L., Agbayani A., Carlson J., Champe M., Chavez C., Dorsett V., Dresnek D., Farfan D., Frise E., George R., Gonzalez M., Guarin H., Kronmiller B., Li P., Liao G., Miranda A. , Mungall C.J., Nunoo J., Pacleb J., Paragas V., Park S., Patel S., Phouanenavong S., Wan K., Yu C., Lewis S.E., Rubin G.M., Celniker S. Submitted (NOV-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BT001269 mRNA. Translation: AAN71025.1.
3D structure databases
ProteinModelPortal	Q8IHG0.
SMR	Q8IHG0. Positions 1-347.
ModBase	Search...
Protein-protein interaction databases
STRING	Q8IHG0.
Proteomic databases
PRIDE	Q8IHG0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Organism-specific databases
FlyBase	FBgn0026479. Drp1.
Phylogenomic databases
eggNOG	inNOG07295.
InParanoid	Q8IHG0.
OrthoDB	EOG4P2NH7.
Gene expression databases
ArrayExpress	Q8IHG0.
Bgee	Q8IHG0.
Family and domain databases
InterPro	IPR022812. Dynamin. IPR000375. Dynamin_central. IPR001401. Dynamin_GTPase. IPR019762. Dynamin_GTPase_CS. IPR003130. GED. IPR020850. GTPase_effector_domain_GED. [Graphical view]
Pfam	PF01031. Dynamin_M. 1 hit. PF00350. Dynamin_N. 1 hit. PF02212. GED. 1 hit. [Graphical view]
PRINTS	PR00195. DYNAMIN.
SMART	SM00053. DYNc. 1 hit. SM00302. GED. 1 hit. [Graphical view]
PROSITE	PS00410. DYNAMIN. 1 hit. PS51388. GED. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q8IHG0_DROME

Accession

Primary (citable) accession number: Q8IHG0

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2003
Last sequence update:	March 1, 2003
Last modified:	November 16, 2011
This is version 49 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)