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Protein
Submitted name:

U5 small nuclear ribonucleoprotein-specific protein, putative

Gene

PFD1060w

Organism
Plasmodium falciparum (isolate 3D7)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  • ATP binding Source: UniProtKB-KW
  • ATP-dependent RNA helicase activity Source: GeneDB
  • nucleic acid binding Source: InterPro

GO - Biological processi

  • RNA splicing, via transesterification reactions Source: GeneDB
Complete GO annotation...

Keywords - Molecular functioni

HelicaseUniRule annotation, Hydrolase, RibonucleoproteinImported

Keywords - Ligandi

ATP-binding, Nucleotide-binding, Viral nucleoproteinImported

Names & Taxonomyi

Protein namesi
Submitted name:
U5 small nuclear ribonucleoprotein-specific protein, putativeImported
Gene namesi
ORF Names:PFD1060wImported
OrganismiPlasmodium falciparum (isolate 3D7)Imported
Taxonomic identifieri36329 [NCBI]
Taxonomic lineageiEukaryotaAlveolataApicomplexaAconoidasidaHaemosporidaPlasmodiidaePlasmodiumPlasmodium (Laverania)
ProteomesiUP000001450 Componenti: Chromosome 4

Organism-specific databases

EuPathDBiPlasmoDB:PF3D7_0422500.

Subcellular locationi

GO - Cellular componenti

  • spliceosomal complex Source: GeneDB
Complete GO annotation...

Keywords - Cellular componenti

Virion

PTM / Processingi

Proteomic databases

PRIDEiQ8IFP1.

Interactioni

Protein-protein interaction databases

IntActiQ8IFP1. 3 interactions.
MINTiMINT-1569750.

Structurei

3D structure databases

ProteinModelPortaliQ8IFP1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000157749.
InParanoidiQ8IFP1.
KOiK12854.
PhylomeDBiQ8IFP1.

Family and domain databases

Gene3Di2.60.40.150. 1 hit.
3.40.50.300. 8 hits.
InterProiIPR003593. AAA+_ATPase.
IPR000008. C2_dom.
IPR011545. DEAD/DEAH_box_helicase_dom.
IPR014001. Helicase_ATP-bd.
IPR001650. Helicase_C.
IPR014756. Ig_E-set.
IPR027417. P-loop_NTPase.
IPR004179. Sec63-dom.
[Graphical view]
PfamiPF00270. DEAD. 2 hits.
PF00271. Helicase_C. 1 hit.
PF02889. Sec63. 2 hits.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
SM00487. DEXDc. 1 hit.
SM00490. HELICc. 1 hit.
SM00611. SEC63. 2 hits.
SM00973. Sec63. 2 hits.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 7 hits.
SSF81296. SSF81296. 3 hits.
PROSITEiPS51192. HELICASE_ATP_BIND_1. 1 hit.
PS51194. HELICASE_CTER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8IFP1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAEEYEKFKR FEYRMNSNLV LQREGPISNT KEPTGESESL VGRLKYKMGD
60 70 80 90 100
KVEYSNKNKK NIMLVQDNKE MAINRNKRKD IFDDDKYNRR SNKKIRHKEK
110 120 130 140 150
SVLNVNIEDI FLYKPTTKYT EEIYTKLMSK IRFLLGDNTG DIINSACNEI
160 170 180 190 200
LYILKNEELN NEEKKKQVES ELEIYINDDI FIEINNLSKE IYDFNKQEEG
210 220 230 240 250
EYVENDEGVA VIFEEDDDYF NIGRNITRGY INDHETMELQ ELSDDNEEED
260 270 280 290 300
ISEDDDGDDE EEDDEEADAE EADDEDGDDE DGDDEEGDDE YGENEDGDDN
310 320 330 340 350
NNNNNNNNNS VRRKKKKKGN QINHLKSYDK KNKKFENYLS LKNTNKNLYY
360 370 380 390 400
DEENKNVQDN DELNINVIDS HWLQRELNKI FPDPSLCLDK EKEVLNVLNI
410 420 430 440 450
YDIQESENKL MHILKYENFH IARVLIKNRW KIYYCTLLGQ AQTEEEKEEI
460 470 480 490 500
KKEMKKTEEG QDILDELCNF KNVRKNKQSE FSKIIRKEAD NLFGKKKIND
510 520 530 540 550
YNKKGNMSDY TYIHDDDDND DNNDDNNDDN NDDDNNDDDD EEKEEGPKYY
560 570 580 590 600
DEENVSDDDN YYESTKLYNS DSQGEDANKK ININAKDVKN IKGVKEEDND
610 620 630 640 650
GGSGKEDNEP TQKSFYNNMK YKFIDLEKLE TKEKNKDIFF NKEVILPPES
660 670 680 690 700
KRIERKEYDE IIISSMKDNK MDGMKRTKNN KMNYYTSPEE IKLIHINELP
710 720 730 740 750
EWTHEVFSCV NITKLNPIQS KVYDVAFNKY EENMLICAPT GSGKTNIALL
760 770 780 790 800
CILNVINSYR LTSGNINRKD FKIVYISPMK ALVNEQVQSF NLRLKCMNIK
810 820 830 840 850
VSELTGDVNL STKELDDSQI IVMTPEKFDV ISRKWNEKIL LHKIKLIIFD
860 870 880 890 900
EIHLLNEMRG NVLESIIARI NRYMDNTMVY DMGDVADGSS GGIRGKNKDA
910 920 930 940 950
NRYNNNDDKK NDDNNNDDKK NDDNNNDDKK NDDNNNDDDD NYNGGGVNSV
960 970 980 990 1000
RQNKYGENHI SIRRKKIRLV GLSATLPNYE DVGIFLRAHI ERGIFYFDHS
1010 1020 1030 1040 1050
FRPVQIEQHY IGIKEKKGIK KYALMNELTY EKVLEEAGKN QILIFVHSRK
1060 1070 1080 1090 1100
ETYRTSKLLI DRFMKSDNLS KFLIDKKISS EILLSEKEHV INEELKEILP
1110 1120 1130 1140 1150
FGFGIHHAGL KRLDRKLVED LFSDRHIQVL VCTSTLAWGI NLPAHTVIIK
1160 1170 1180 1190 1200
GTSVYNINIG DFDELSSMDV LQMVGRSGRP QYDKSGKAII ITDHKNLQLY
1210 1220 1230 1240 1250
LSLNNEQLFI ESTLLHNIVN IINAEIVLKN IQNMDDAMNW LEHTYMYIRM
1260 1270 1280 1290 1300
LKCPSLYGVI INSNDKIKGI EEFKDIIDMN NKTKKHNNNN NNNINGGNNN
1310 1320 1330 1340 1350
NNNNINGGNN NNNNNINGGN NNNSNNVMDY MSILKTNYKY NKFMEKIKRR
1360 1370 1380 1390 1400
MYNILYSCFL ILEKYDLIKY NKKLNTVSST YIGKISSYYY VDYKSIDIYN
1410 1420 1430 1440 1450
KKLNKYTNEI DLLKIFTMSN EFKNIFIRDE EKTELSIIME KLPIPVKESI
1460 1470 1480 1490 1500
NIPYTKINIL LQLYLSNIIL NGYIINADMV YIHQNALRIF RSFFEISLKK
1510 1520 1530 1540 1550
NSYNLIKLTL KFCKMIERRM WSTMTPLRQF GLLSTELIRI IEKKNITFKN
1560 1570 1580 1590 1600
YLTMNLNEYI TIFKNKKIAK NIYKLVHHFP KLELNAYIQP INHKILKVDL
1610 1620 1630 1640 1650
NIAPDFIYNP KYHGYFMLFW VFVFDISNES ILHYDLFTLK KNYKNDILNQ
1660 1670 1680 1690 1700
TQRYNNNGNN SNMYNPSDVL DDHVLTFFLP INDNPFYIVK VISDKWLECE
1710 1720 1730 1740 1750
ATINLYLKDL ILPSQNFYST QLLDLQPLPI HSIKYDKAHT FFNNIRNLHY
1760 1770 1780 1790 1800
FNSIHTQIFS SIFENNGNVL IASSNSKHYL IPAELGMIKI LKFLHCFYNF
1810 1820 1830 1840 1850
INTYIKKEKD VYKIINDKKL ADLLYNNNLI DLIKIVYIAP LDDVIIKTFK
1860 1870 1880 1890 1900
NWQAMKKTFD LKMCILTGDI QIDMKLLQTH HIILSNPSNY DNISKKWRRK
1910 1920 1930 1940 1950
KILQTVSFYI FDHMELLDTV QGGIMEILIS RIRYISTQLN INKSEKKNQH
1960 1970 1980 1990 2000
NNDNNNNDNL IMSILNIDMI KMDNVEDDNN KKNIIHNNNN NNSNSKKDDF
2010 2020 2030 2040 2050
VQTINALQNF TIDNIYDYIG LNRILCLSSC SLYNSKDFAE WIGCKKNDYY
2060 2070 2080 2090 2100
NFLSTVRDIP IEIYLHAVNI MNKQNRYISM QRQVYQNIRK LKNIPKKKKM
2110 2120 2130 2140 2150
QNVIIFVTDQ KLCKTLALDL ILSAYNDNFK YFSLFENYED DKYDTSKSST
2160 2170 2180 2190 2200
NPYDPKNEEK EKKKGGGWIS NLFTYNKDDK IGRHNESNDL INNNSHDDTT
2210 2220 2230 2240 2250
SNNLQKSGTF RSNDLYNNGT NVEELAKSIH NMINLNISNM DIIKNKEVAE
2260 2270 2280 2290 2300
NNMNVASSNN NNNNNSNSNN IYKNGRKRSN NRNNKNEEHV FDYINDKMLR
2310 2320 2330 2340 2350
QFMKKGICYL HNNMTEIEKK IVEILFDKKT IQILIVSYDY IYSLNVYANN
2360 2370 2380 2390 2400
VIILDTIITH FHNNKEEDYS IQNILEMISY AGRQNEDTKA FVYIYTYITK
2410 2420 2430 2440 2450
KEYYKNFIYE PLTVESNIED NLPNFLNNEI VMSTIENYQD AIDWLTWSFF
2460 2470 2480 2490 2500
YRRIKKNPNY YGLKGISNEH ISDYLSELIE NNMEILSFAN CINIEEQTMD
2510 2520 2530 2540 2550
IKPCNLGIIS SFYNLDYHII HFFNQYVLSL KTLKKSRIFE IICLSNIFND
2560 2570 2580 2590 2600
ILKIHNYDIF LCLKIAQACN NVQVTYEFLK LSINNENTLK NANIEDNLNK
2610 2620 2630 2640 2650
DTKSEDYKKD QYINLLQFMS VPMYFTSHLK AFILLQAHIH RYSLPLNYIQ
2660 2670 2680 2690 2700
ETKTVLLKAY KLINSLIDVI SSNNILNFCL FVMEVSQMLT QSMKSTDQSN
2710 2720 2730 2740 2750
LYQLPHFDEH LIKKANDLEI LDVYDLINAE DEPRDILLKH LNEKQRSEIA
2760 2770 2780 2790 2800
NVCNIFPIIE VQYEIDLDKS YKVNEIAQLN LTIERDLTDD AVIFAHSLYL
2810 2820 2830 2840 2850
PFEKEEMWWI VIGIKKMNLL LSIKKLSLLK SVNNIKINFE LPDKPNTYDV
2860 2870
VIYVINDCYV GCDQEYEFKI NVEE
Length:2,874
Mass (Da):337,908
Last modified:March 1, 2003 - v1
Checksum:iEE6EDC4E7E4A6E9B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL844503 Genomic DNA. Translation: CAD49259.1.
RefSeqiXP_001351528.1. XM_001351492.1.

Genome annotation databases

EnsemblProtistsiPFD1060w:mRNA; PFD1060w:pep; PFD1060w.
GeneIDi812456.
KEGGipfa:PFD1060w.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL844503 Genomic DNA. Translation: CAD49259.1.
RefSeqiXP_001351528.1. XM_001351492.1.

3D structure databases

ProteinModelPortaliQ8IFP1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ8IFP1. 3 interactions.
MINTiMINT-1569750.

Proteomic databases

PRIDEiQ8IFP1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsiPFD1060w:mRNA; PFD1060w:pep; PFD1060w.
GeneIDi812456.
KEGGipfa:PFD1060w.

Organism-specific databases

EuPathDBiPlasmoDB:PF3D7_0422500.

Phylogenomic databases

HOGENOMiHOG000157749.
InParanoidiQ8IFP1.
KOiK12854.
PhylomeDBiQ8IFP1.

Family and domain databases

Gene3Di2.60.40.150. 1 hit.
3.40.50.300. 8 hits.
InterProiIPR003593. AAA+_ATPase.
IPR000008. C2_dom.
IPR011545. DEAD/DEAH_box_helicase_dom.
IPR014001. Helicase_ATP-bd.
IPR001650. Helicase_C.
IPR014756. Ig_E-set.
IPR027417. P-loop_NTPase.
IPR004179. Sec63-dom.
[Graphical view]
PfamiPF00270. DEAD. 2 hits.
PF00271. Helicase_C. 1 hit.
PF02889. Sec63. 2 hits.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
SM00487. DEXDc. 1 hit.
SM00490. HELICc. 1 hit.
SM00611. SEC63. 2 hits.
SM00973. Sec63. 2 hits.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 7 hits.
SSF81296. SSF81296. 3 hits.
PROSITEiPS51192. HELICASE_ATP_BIND_1. 1 hit.
PS51194. HELICASE_CTER. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Isolate 3D7Imported.
  2. "Sequence of Plasmodium falciparum chromosomes 1, 3-9 and 13."
    Hall N., Pain A., Berriman M., Churcher C., Harris B., Harris D., Mungall K., Bowman S., Atkin R., Baker S., Barron A., Brooks K., Buckee C.O., Burrows C., Cherevach I., Chillingworth C., Chillingworth T., Christodoulou Z.
    , Clark L., Clark R., Corto C., Cronin A., Davies R., Davies P., Dear P., Dearden F., Doggett J., Feltwell T., Goble A., Goodhead I., Gwilliam R., Hamlin N., Hance Z., Harper D., Hauser H., Hornsby T., Holroyd S., Horrocks P., Humphray S., Jagels K., James D., Johnson D., Kerhornou A., Knight A., Kontfortov B., Keyes S., Larke N., Lawson D., Lennard N., Line A., Maddison M., McLean J., Mooney P., Moule S., Murphy L., Oliver K., Ormond D., Price C., Quail M.A., Rabbinowitsch E., Rajandream M-A., Rutter S., Rutherford K.M., Sanders M., Simmonds M., Seeger K., Sharp S., Smith R., Squares R., Squares S., Stevens K., Taylor K., Tivey A., Unwin L., Whitehead S., Woodward J., Sulston J.E., Craig A., Newbold C., Barrell B.G.
    Nature 419:527-531(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Isolate 3D7Imported.

Entry informationi

Entry nameiQ8IFP1_PLAF7
AccessioniPrimary (citable) accession number: Q8IFP1
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: July 22, 2015
This is version 89 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.