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Q8IES4 (Q8IES4_PLAF7) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 71. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
DNA ligase RuleBase RU000617
EC=6.5.1.1 RuleBase RU000617
Gene names
Name:PfLigI EMBL CAD52175.1
ORF Names:MAL13P1.22 EMBL CAD52175.1
OrganismPlasmodium falciparum (isolate 3D7) [Reference proteome] EMBL CAD52175.1
Taxonomic identifier36329 [NCBI]
Taxonomic lineageEukaryota › Alveolata › Apicomplexa › Aconoidasida › Haemosporida › Plasmodium › Plasmodium (Laverania) ›

Protein attributes

Sequence length912 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m). RuleBase RU000617

Sequence similarities

Belongs to the ATP-dependent DNA ligase family. RuleBase RU004196

Sequences

Sequence LengthMass (Da)Tools
Q8IES4 [UniParc].

Last modified March 1, 2003. Version 1.
Checksum: FFC1EC4B2428DD77

FASTA912104,506
        10         20         30         40         50         60 
MNFLILVVLI KMVVCKIINY VRSDYNFMLS FLRTRKIFSH KKIYFNFKVS KNITKNSSSN 

        70         80         90        100        110        120 
SYSDILKCFS FPRKGTNDKT KENETFEKGE VKEEEEEKDK NVKRKIINES SKNKRAKVKN 

       130        140        150        160        170        180 
ENDVIKKGSL FNCVVREDEK VNDLSSPKFN PVHFNINDLY LSEKDKEKHK FKDSLLFTFL 

       190        200        210        220        230        240 
TNAFNQIEEL KGSGTGSKKN VSIILSNIFR VLIYYSPNDL IPAVYITLNK VAPDYLNVEA 

       250        260        270        280        290        300 
GVGEALILKT MSEAYSRTES SIKKDLQQIE DLGIIAENCS CKMRTIFPLP RLTIQSVFHE 

       310        320        330        340        350        360 
LKSIPNLIGS NSQQKKREVI KKLLVSAKTS EAKYIVRFLQ QRLRIGVNSA TVVQALSYAF 

       370        380        390        400        410        420 
ILTRPSIPDD IIKRGKEINE NLINGKLDGT NNLINKSNNK TEEWLTQSGD RNCIKEENLN 

       430        440        450        460        470        480 
DELLSKDDIN KCENMDSLIN EIRIRNEKIN KPNIFYNLIE KVGDTRLLPL FFKELKNIYC 

       490        500        510        520        530        540 
EENNDIDIFE CMEKSVKSAL CELPNIEIII QNLLNGDDMN TLSKKCTVKT GIPVQPMLAK 

       550        560        570        580        590        600 
PTKGVQEVLD RFNNVTFTCE YKYDGERAQI HYIDKDNIKI FSRNLETMTE KYPDVIQIIK 

       610        620        630        640        650        660 
DQIGENVKEC IIDSEVVAYD IVNNKILPFQ VLTTRKRKDV DIENIKVKVC LFPFDLICCN 

       670        680        690        700        710        720 
GIPVIKEPLA VRRKLLYSLL KSKDGVLSYA THSEMNNIED IDMFLQDAIE NNCEGLMVKT 

       730        740        750        760        770        780 
LVENASYEPS RRSLNWLKVK KDYVEGLSDS VDLVPIAGYY GKGKRSGVYG AFVLAAYNSE 

       790        800        810        820        830        840 
TENFQTVCKA GTGFSDEILS TLYETLSEKI IPNKKSYYEV SDKLNPDVWF DAHYVWEVKA 

       850        860        870        880        890        900 
ADLSLSPVHT AAIGIYADDK GIGLRFPRFL RLREDKNAEQ ATTTQQIVDF YEAQFSSNKN 

       910 
KNIDYNDDTE SE

« Hide

References

[1]"Genome sequence of the human malaria parasite Plasmodium falciparum."
Gardner M.J., Hall N., Fung E., White O., Berriman M., Hyman R.W., Carlton J.M., Pain A., Nelson K.E., Bowman S., Paulsen I.T., James K.D., Eisen J.A., Rutherford K.M., Salzberg S.L., Craig A., Kyes S., Chan M.-S. expand/collapse author list , Nene V., Shallom S.J., Suh B., Peterson J., Angiuoli S., Pertea M., Allen J., Selengut J., Haft D., Mather M.W., Vaidya A.B., Martin D.M.A., Fairlamb A.H., Fraunholz M.J., Roos D.S., Ralph S.A., McFadden G.I., Cummings L.M., Subramanian G.M., Mungall C., Venter J.C., Carucci D.J., Hoffman S.L., Newbold C., Davis R.W., Fraser C.M., Barrell B.G.
Nature 419:498-511(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Isolate 3D7.
[2]"Sequence of Plasmodium falciparum chromosomes 1, 3-9 and 13."
Hall N., Pain A., Berriman M., Churcher C.M., Harris B., Harris D., Mungall K.L., Bowman S., Atkin R., Baker S., Barron A., Brooks K., Buckee C.O., Burrows C., Cherevach I., Chillingworth C., Chillingworth T., Christodoulou Z. expand/collapse author list , Clark L., Clark R., Corton C., Cronin A., Davies R.M., Davis P., Dear P., Dearden F., Doggett J., Feltwell T., Goble A., Goodhead I., Gwilliam R., Hamlin N., Hance Z., Harper D., Hauser H., Hornsby T., Holroyd S., Horrocks P., Humphray S., Jagels K., James K.D., Johnson D., Kerhornou A., Knights A., Konfortov B., Kyes S., Larke N., Lawson D., Lennard N., Line A., Maddison M., Mclean J., Mooney P., Moule S., Murphy L., Oliver K., Ormond D., Price C., Quail M.A., Rabbinowitsch E., Rajandream M.A., Rutter S., Rutherford K.M., Sanders M., Simmonds M., Seeger K., Sharp S., Smith R., Squares R., Squares S., Stevens K., Taylor K., Tivey A., Unwin L., Whitehead S., Woodward J.R., Sulston J.E., Craig A., Newbold C., Barrell B.G.
Nature 419:527-531(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Isolate 3D7.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AL844509 Genomic DNA. Translation: CAD52175.1.
RefSeqXP_001349768.1. XM_001349732.1.

3D structure databases

ProteinModelPortalQ8IES4.
ModBaseSearch...

Protein-protein interaction databases

STRING5833.MAL13P1.22-1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsMAL13P1.22:mRNA; MAL13P1.22:pep; MAL13P1.22.
GeneID813777.
KEGGpfa:MAL13P1.22.

Organism-specific databases

EuPathDBPlasmoDB:PF3D7_1304100.

Phylogenomic databases

HOGENOMHOG000036006.
KOK10747.
OMAETICNIG.
ProtClustDBCLSZ2432498.

Family and domain databases

Gene3D1.10.3260.10. 2 hits.
2.40.50.140. 1 hit.
InterProIPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMSSF50249. Nucleic_acid_OB. 1 hit.
SSF117018. SSF117018. 1 hit.
TIGRFAMsTIGR00574. dnl1. 1 hit.
PROSITEPS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ8IES4_PLAF7
AccessionPrimary (citable) accession number: Q8IES4
Entry history
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: May 1, 2013
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info