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Protein
Submitted name:

DEAD box helicase, putative

Gene

PF3D7_1324500

Organism
Plasmodium falciparum (isolate 3D7)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

Catalytic activityi

ATP + H2O = ADP + phosphate.SAAS annotation

GO - Molecular functioni

  • ATP binding Source: UniProtKB-KW
  • ATP-dependent DNA helicase activity Source: InterPro
  • DNA binding Source: InterPro
  • helicase activity Source: GeneDB

GO - Biological processi

Keywordsi

Molecular functionHelicaseSAAS annotationImported, Hydrolase
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
DEAD box helicase, putativeImported (EC:3.6.4.12Imported)
Gene namesi
ORF Names:PF3D7_1324500Imported
OrganismiPlasmodium falciparum (isolate 3D7)Imported
Taxonomic identifieri36329 [NCBI]
Taxonomic lineageiEukaryotaAlveolataApicomplexaAconoidasidaHaemosporidaPlasmodiidaePlasmodiumPlasmodium (Laverania)
Proteomesi
  • UP000001450 Componenti: Chromosome 13

Organism-specific databases

EuPathDBiPlasmoDB:PF3D7_1324500.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei742 – 762HelicalSequence analysisAdd BLAST21
Transmembranei809 – 831HelicalSequence analysisAdd BLAST23

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • membrane Source: GeneDB

Keywords - Cellular componenti

Membrane

Structurei

3D structure databases

ProteinModelPortaliQ8IE72.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini7 – 460Helicase ATP-bindingInterPro annotationAdd BLAST454

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili227 – 247Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

HOGENOMiHOG000281821.
InParanoidiQ8IE72.
KOiK11273.
OMAiHIICEMK.
PhylomeDBiQ8IE72.

Family and domain databases

InterProiView protein in InterPro
IPR006555. ATP-dep_Helicase_C.
IPR010614. DEAD_2.
IPR014013. Helic_SF1/SF2_ATP-bd_DinG/Rad3.
IPR006554. Helicase-like_DEXD_c2.
IPR027417. P-loop_NTPase.
PfamiView protein in Pfam
PF06733. DEAD_2. 1 hit.
PF13307. Helicase_C_2. 1 hit.
SMARTiView protein in SMART
SM00488. DEXDc2. 1 hit.
SM00491. HELICc2. 1 hit.
SUPFAMiSSF52540. SSF52540. 3 hits.
PROSITEiView protein in PROSITE
PS51193. HELICASE_ATP_BIND_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8IE72-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVERFNEEIK RFFPFEPYKI QLNFMRLFYQ VLTSSNIKKY DNLNLIYEVI
60 70 80 90 100
KQNQNIQGML KDDASNLIFD HLNVLKNEDI KNTEEEHIIC EMKTGSGKSL
110 120 130 140 150
TLLTSLIYWL WKHKMNLFFI KENIELKSTE PDWVKESVIE KVIEKYKHNI
160 170 180 190 200
QQDHKIKENN LNILKKYFSF TDDKIALHKN IKISKKKCEQ HEPVQKNDNF
210 220 230 240 250
VLPDNNDEVR SDYSIDDKDK KKQIFICSRT QSQLNQYFHE LKKIEKKMGE
260 270 280 290 300
DFSINMIIIG SRKHLCINEA FLKKYKNINE LNDCCKNSKC KYKEIYNEKM
310 320 330 340 350
SEKWKKKNGK KKRIFYDSSC SSNSSENEDI ETIDNYILIT KLINNRNVDI
360 370 380 390 400
EDIKDICKNE HIEICPYYLS KENIKNADII LLPYICILNE NIRNNLKINI
410 420 430 440 450
KNNIVIFDES QNIIENINSC NSVSISNHHI LFCKIILNEY IKKYKNVLNN
460 470 480 490 500
NNIIMIKQII VYCNLLLESF TSIQQNLINI NKYTLLSKLD VLNLNNISNF
510 520 530 540 550
LNNSMFCRKI KIFTESLMST YFKNIKKYLH ASFPIFKTTA IYILNEFTQK
560 570 580 590 600
LIKSNLYDYV SIHYNDNYSP TIEHSENNLM NQINHSTRTL NGNNCKDEQN
610 620 630 640 650
IFSTDCDIDK IKNKKRIMTS HGLTPVDSKK NKLQNGNHNT KKELFMNDWD
660 670 680 690 700
DSKDQDVNDV MCKRSNCINN TQKCKNKNIK MSDDNFNNDD KKGFNDDTYN
710 720 730 740 750
NLNIFFEEFF VKKRKDLFNE IEVISVSSCN NFQSITKDCS NVILIGGTLY
760 770 780 790 800
PMEEFLLLFL NYNKNKIKLF SSDYIFKKQN IFARIFSTNL ISSDFIDNTY
810 820 830 840 850
KNRLKKDHLL NLAIYIYMIT FNILYGNIIF FPSYNFLNDF YNFLNKEGEY
860 870 880 890 900
IFNRIKKKKF VFFEKKNDDT IVKNYMNNIE NIKNIDPNLR IQNGCILFCV
910 920 930 940 950
MNGKLSEGIN FYDDLCRNVV VVGIPFIKHD SVVDKNLLRL KYYREYTKDI
960 970 980 990 1000
MNTHDKNDNT KILIYDDVHK MCESYETKYA MKIINQCIGR SLRHVNDFSS
1010 1020 1030 1040 1050
FFFLDYRFSK KEIFQNLPSF IKTHINDIDN IIYKNYDDTE NSYIKIKEHF
1060 1070 1080 1090
QDTYANIKHF YTNQMSSCGF NFQPISQDLI SNLVKDLDML KKFHDTKNK
Length:1,099
Mass (Da):130,702
Last modified:March 1, 2003 - v1
Checksum:i84B0D76E2E32CE14
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL844509 Genomic DNA. Translation: CAD52393.1.
RefSeqiXP_001349985.1. XM_001349949.1.

Genome annotation databases

EnsemblProtistsiCAD52393; CAD52393; PF3D7_1324500.
GeneDBiPF3D7_1324500.1:pep.
GeneIDi813685.
KEGGipfa:MAL13P1.134.

Similar proteinsi

Entry informationi

Entry nameiQ8IE72_PLAF7
AccessioniPrimary (citable) accession number: Q8IE72
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: December 20, 2017
This is version 88 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported