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Protein
Submitted name:

Calcium-dependent protein kinase 5

Gene

PF3D7_1337800

Organism
Plasmodium falciparum (isolate 3D7)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Protein predictedi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Calcium bindingi438 – 449PROSITE-ProRule annotationAdd BLAST12
Calcium bindingi473 – 484PROSITE-ProRule annotationAdd BLAST12
Calcium bindingi509 – 520PROSITE-ProRule annotationAdd BLAST12
Calcium bindingi547 – 558PROSITE-ProRule annotationAdd BLAST12

GO - Molecular functioni

  • ATP binding Source: InterPro
  • calcium-dependent protein serine/threonine kinase activity Source: GO_Central
  • calcium ion binding Source: InterPro
  • calmodulin binding Source: GO_Central
  • calmodulin-dependent protein kinase activity Source: GeneDB
  • protein serine/threonine kinase activity Source: GeneDB

GO - Biological processi

  • exit from host cell Source: GeneDB
  • intracellular signal transduction Source: GO_Central
  • peptidyl-serine phosphorylation Source: GO_Central
  • protein autophosphorylation Source: GO_Central
  • protein phosphorylation Source: GeneDB
  • response to drug Source: GeneDB

Keywordsi

Molecular functionKinaseImported, Transferase
LigandCalciumPROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Calcium-dependent protein kinase 5Imported (EC:2.7.11.17Imported)
Gene namesi
ORF Names:PF3D7_1337800Imported
OrganismiPlasmodium falciparum (isolate 3D7)Imported
Taxonomic identifieri36329 [NCBI]
Taxonomic lineageiEukaryotaAlveolataApicomplexaAconoidasidaHaemosporidaPlasmodiidaePlasmodiumPlasmodium (Laverania)
Proteomesi
  • UP000001450 Componenti: Chromosome 13

Organism-specific databases

EuPathDBiPlasmoDB:PF3D7_1337800.

Subcellular locationi

GO - Cellular componenti

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliQ8IDV5.
SMRiQ8IDV5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini125 – 379Protein kinaseInterPro annotationAdd BLAST255
Domaini425 – 460EF-handInterPro annotationAdd BLAST36
Domaini462 – 495EF-handInterPro annotationAdd BLAST34
Domaini496 – 531EF-handInterPro annotationAdd BLAST36
Domaini534 – 568EF-handInterPro annotationAdd BLAST35

Phylogenomic databases

HOGENOMiHOG000233030.
InParanoidiQ8IDV5.
KOiK13412.
OMAiTCVAYQL.
PhylomeDBiQ8IDV5.

Family and domain databases

CDDicd00051. EFh. 1 hit.
InterProiView protein in InterPro
IPR011992. EF-hand-dom_pair.
IPR018247. EF_Hand_1_Ca_BS.
IPR002048. EF_hand_dom.
IPR011009. Kinase-like_dom_sf.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
PfamiView protein in Pfam
PF13499. EF-hand_7. 2 hits.
PF00069. Pkinase. 1 hit.
SMARTiView protein in SMART
SM00054. EFh. 4 hits.
SM00220. S_TKc. 1 hit.
SUPFAMiSSF47473. SSF47473. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEiView protein in PROSITE
PS00018. EF_HAND_1. 4 hits.
PS50222. EF_HAND_2. 4 hits.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8IDV5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKETEVEDMD TNRKDGKIKK KEKIVNMKNE EVKSTTKSTL ADSDEDYSII
60 70 80 90 100
TLCTKCLSKK LEDNKNRIIL DSKAFKDNRL KGRCSVSSNE DPLDNKLNLS
110 120 130 140 150
PYFDRSQIIQ EIILMNNDEL SDVYEIDRYK LGKGSYGNVV KAVSKRTGQQ
160 170 180 190 200
RAIKIIEKKK IHNIERLKRE ILIMKQMDHP NIIKLYEVYE DNEKLYLVLE
210 220 230 240 250
LCDGGELFDK IVKYGSFSEY EAYKIMKQIF SALYYCHSKN IMHRDLKPEN
260 270 280 290 300
ILYVDNTEDS PIQIIDWGFA SKCMNNHNLK SVVGTPYYIA PEILRGKYDK
310 320 330 340 350
RCDIWSSGVI MYILLCGYPP FNGKNNDEIL KKVEKGEFVF DSNYWARVSD
360 370 380 390 400
DAKDLICQCL NYNYKERIDV EQVLKHRWFK KFKSNNLIIN KTLNKTLIEK
410 420 430 440 450
FKEFHKLCKI KKLAVTCIAY QLNEKDIGKL KKTFEAFDHN GDGVLTISEI
460 470 480 490 500
FQCLKVNDNE FDRELYFLLK QLDTDGNGLI DYTEFLAACL DHSIFQQDVI
510 520 530 540 550
CRNAFNVFDL DGDGVITKDE LFKILSFSAV QVSFSKEIIE NLIKEVDSNN
560
DGFIDYDEFY KMMTGVKE
Length:568
Mass (Da):66,248
Last modified:March 1, 2003 - v1
Checksum:iBE587C25EDE12E27
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL844509 Genomic DNA. Translation: CAD52514.1.
RefSeqiXP_001350105.1. XM_001350069.1.

Genome annotation databases

EnsemblProtistsiCAD52514; CAD52514; PF3D7_1337800.
GeneDBiPF3D7_1337800.1:pep.
GeneIDi814178.
KEGGipfa:PF13_0211.

Similar proteinsi

Entry informationi

Entry nameiQ8IDV5_PLAF7
AccessioniPrimary (citable) accession number: Q8IDV5
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: November 22, 2017
This is version 115 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported