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Protein

Nucleoside diphosphate kinase

Gene

PF3D7_1366500

Organism
Plasmodium falciparum (isolate 3D7)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Catalytic activityi

ATP + nucleoside diphosphate = ADP + nucleoside triphosphate.UniRule annotation

GO - Molecular functioni

  • ATP binding Source: GeneDB
  • magnesium ion binding Source: GeneDB
  • nucleoside diphosphate kinase activity Source: GeneDB

GO - Biological processi

  • CTP biosynthetic process Source: GeneDB
  • GTP biosynthetic process Source: GeneDB
  • UTP biosynthetic process Source: GeneDB

Keywordsi

Molecular functionKinaseUniRule annotationImported, Transferase
LigandATP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-PFA-499943 Interconversion of nucleotide di- and triphosphates
R-PFA-6798695 Neutrophil degranulation

Names & Taxonomyi

Protein namesi
Recommended name:
Nucleoside diphosphate kinaseUniRule annotation (EC:2.7.4.6UniRule annotation)
Gene namesi
ORF Names:PF3D7_1366500Imported
OrganismiPlasmodium falciparum (isolate 3D7)Imported
Taxonomic identifieri36329 [NCBI]
Taxonomic lineageiEukaryotaAlveolataApicomplexaAconoidasidaHaemosporidaPlasmodiidaePlasmodiumPlasmodium (Laverania)
Proteomesi
  • UP000001450 Componenti: Chromosome 13

Organism-specific databases

EuPathDBiPlasmoDB:PF3D7_1366500

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Proteomic databases

PRIDEiQ8ID43

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1XIQX-ray3.05A/B/C/D/E/F1-149[»]
ProteinModelPortaliQ8ID43
SMRiQ8ID43
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ8ID43

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 138NDKInterPro annotationAdd BLAST138

Sequence similaritiesi

Belongs to the NDK family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000224564
InParanoidiQ8ID43
KOiK00940
OMAiWADGGQH
PhylomeDBiQ8ID43

Family and domain databases

Gene3Di3.30.70.141, 1 hit
HAMAPiMF_00451 NDP_kinase, 1 hit
InterProiView protein in InterPro
IPR034907 NDK-like_dom
IPR036850 NDK-like_dom_sf
IPR001564 Nucleoside_diP_kinase
IPR023005 Nucleoside_diP_kinase_AS
PfamiView protein in Pfam
PF00334 NDK, 1 hit
PRINTSiPR01243 NUCDPKINASE
SMARTiView protein in SMART
SM00562 NDK, 1 hit
SUPFAMiSSF54919 SSF54919, 1 hit
PROSITEiView protein in PROSITE
PS00469 NDP_KINASES, 1 hit

Sequencei

Sequence statusi: Complete.

Q8ID43-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEKSFIMIKP DGVQRGLVGT IIKRFEKKGY KLIAIKMLNP TEEILKEHYK
60 70 80 90 100
ELSDQPFFKN LVAYISKGPV VAMVWEGVDM VKQGRKLIGE TNPLTSNTGT
110 120 130 140
IRGDFCLEVS KNVIHGSDSV ASANKEINIW FKAEELTQWK HHMKEWICS
Length:149
Mass (Da):17,012
Last modified:March 1, 2003 - v1
Checksum:iF8886BB3B0E18DCC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL844509 Genomic DNA Translation: CAD52785.1
RefSeqiXP_001350376.1, XM_001350340.1

Genome annotation databases

EnsemblProtistsiCAD52785; CAD52785; PF3D7_1366500
GeneDBiPF3D7_1366500.1:pep
GeneIDi814308
KEGGipfa:PF13_0349

Similar proteinsi

Entry informationi

Entry nameiQ8ID43_PLAF7
AccessioniPrimary (citable) accession number: Q8ID43
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: May 23, 2018
This is version 108 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

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