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Protein

RNA helicase

Gene

PF3D7_0721300

Organism
Plasmodium falciparum (isolate 3D7)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + H2O = ADP + phosphate.SAAS annotation

GO - Molecular functioni

  • ATP binding Source: GeneDB
  • ATP-dependent RNA helicase activity Source: GeneDB
  • RNA binding Source: GeneDB

GO - Biological processi

  • RNA metabolic process Source: GeneDB
  • RNA secondary structure unwinding Source: GO_Central

Keywordsi

Molecular functionHelicaseSAAS annotationImported, Hydrolase, RNA-bindingSAAS annotation
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
RNA helicaseSAAS annotation (EC:3.6.4.13SAAS annotation)
Gene namesi
ORF Names:PF3D7_0721300Imported
OrganismiPlasmodium falciparum (isolate 3D7)Imported
Taxonomic identifieri36329 [NCBI]
Taxonomic lineageiEukaryotaAlveolataApicomplexaAconoidasidaHaemosporidaPlasmodiidaePlasmodiumPlasmodium (Laverania)
Proteomesi
  • UP000001450 Componenti: Chromosome 7

Organism-specific databases

EuPathDBiPlasmoDB:PF3D7_0721300.

Subcellular locationi

GO - Cellular componenti

Structurei

3D structure databases

ProteinModelPortaliQ8IBN8.
SMRiQ8IBN8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini173 – 201Q_MOTIFInterPro annotationAdd BLAST29
Domaini204 – 433Helicase ATP-bindingInterPro annotationAdd BLAST230
Domaini593 – 782Helicase C-terminalInterPro annotationAdd BLAST190

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi173 – 201Q motifPROSITE-ProRule annotationAdd BLAST29

Sequence similaritiesi

Belongs to the DEAD box helicase family.SAAS annotation

Phylogenomic databases

InParanoidiQ8IBN8.
KOiK14806.
OMAiTCASSAQ.
PhylomeDBiQ8IBN8.

Family and domain databases

CDDicd00079. HELICc. 1 hit.
InterProiView protein in InterPro
IPR011545. DEAD/DEAH_box_helicase_dom.
IPR025313. DUF4217.
IPR014001. Helicase_ATP-bd.
IPR001650. Helicase_C.
IPR027417. P-loop_NTPase.
IPR000629. RNA-helicase_DEAD-box_CS.
IPR014014. RNA_helicase_DEAD_Q_motif.
PfamiView protein in Pfam
PF00270. DEAD. 1 hit.
PF13959. DUF4217. 1 hit.
PF00271. Helicase_C. 1 hit.
SMARTiView protein in SMART
SM00487. DEXDc. 1 hit.
SM01178. DUF4217. 1 hit.
SM00490. HELICc. 1 hit.
SUPFAMiSSF52540. SSF52540. 4 hits.
PROSITEiView protein in PROSITE
PS00039. DEAD_ATP_HELICASE. 1 hit.
PS51192. HELICASE_ATP_BIND_1. 1 hit.
PS51194. HELICASE_CTER. 1 hit.
PS51195. Q_MOTIF. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8IBN8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNKHDQKKKR NKQHTDNVMG KKSKGFIKNK KNIGESGNEK KRNNNFNNIW
60 70 80 90 100
KKKKRSGNSE KDQVDILGLL KGDSENMNDD DDNNMNDDYN NNNIKGDYNN
110 120 130 140 150
NNIKDDDVDD DDYDDDDDDN FDENKNCNDN CSSKHKRNVP SKKEHDILEL
160 170 180 190 200
NNINFNETRK KMINYKNIFD GKFCDLKYIL SESLINTLEK NEFIKMTSIQ
210 220 230 240 250
KMSIPLFFKP NDIFLKSMTG SGKTLCYAIP SIEKILNMKE KVKITRDMGI
260 270 280 290 300
FVLVLSPTRE LAIQINNLFC ILTKPYPYIV ASCITGGEKK KSEKNRLKKG
310 320 330 340 350
ISILTCTPGR LLDHLENTKS LKLTFLKMVI LDEADKIIYL GTQDKIKLIY
360 370 380 390 400
DMIRKIKQEE FSKVHKKKKK EENEVLDHIN DTNMSDMNNI SNDHSNDYEQ
410 420 430 440 450
FILDKFQMIF ISATLNHAMK TLANYCLTNN TMWIEKEKKN GINGGNKNDE
460 470 480 490 500
TKQKSNDMIS CMNRENSPLN IHNNDDNDDN DDNDENNGDN NNNNDDNNNN
510 520 530 540 550
NDDNNNKNND DDNNNTYELP EQLKQYCILI DMKQKFICLI YMLLDCIEKK
560 570 580 590 600
KKPVVFLSNH HSVEYLQILL KNIYWPTDVN KKNIEVNKKL NEKITPVLER
610 620 630 640 650
EDEKLLRKHL EQNILNNNYY NNNYNVGNIS YKNINLEEIQ NEDELNDEPG
660 670 680 690 700
NLYNINADKH KRIYLFNNVN IYILHGNLSK EDRLGNFMDF SKTNNSILLC
710 720 730 740 750
TDIISRGIHF DSLSVVIQYD PPQILEEYIH KVGRTARLNK QGSAYLFLLK
760 770 780 790 800
SQKQFLNILK NKNIQLKIIL GNTIINHFKK FCIPNFLKSV GKDILNFLHN
810 820 830 840 850
HMQTIVKSNN TLMEKGTSAF LCTITSFYST SKNLRSIFNA KDIHLGHLAY
860 870 880 890
TFLLEKTPKQ ISKYKKEQNY INIKKQTVLS KKEKRLLKSK QFQKKQKRK
Length:899
Mass (Da):105,030
Last modified:March 1, 2003 - v1
Checksum:i9B7BE69348B07885
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL844506 Genomic DNA. Translation: CAD50961.1.
RefSeqiXP_001349115.1. XM_001349079.1.

Genome annotation databases

EnsemblProtistsiCAD50961; CAD50961; PF3D7_0721300.
GeneDBiPF3D7_0721300.1:pep.
GeneIDi2654935.
KEGGipfa:MAL7P1.113.

Similar proteinsi

Entry informationi

Entry nameiQ8IBN8_PLAF7
AccessioniPrimary (citable) accession number: Q8IBN8
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: October 25, 2017
This is version 114 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported