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Protein
Submitted name:

Exonuclease I, putative

Gene

PF3D7_0725000

Organism
Plasmodium falciparum (isolate 3D7)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

  • 5'-3' exodeoxyribonuclease activity Source: InterPro
  • 5'-3' exonuclease activity Source: GeneDB

GO - Biological processi

  • DNA recombination Source: GeneDB
  • mismatch repair Source: GeneDB

Keywordsi

Molecular functionExonucleaseImported, Hydrolase, Nuclease

Enzyme and pathway databases

ReactomeiR-PFA-5358565 Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)

Names & Taxonomyi

Protein namesi
Submitted name:
Exonuclease I, putativeImported (EC:3.1.16.1Imported)
Gene namesi
ORF Names:PF3D7_0725000Imported
OrganismiPlasmodium falciparum (isolate 3D7)Imported
Taxonomic identifieri36329 [NCBI]
Taxonomic lineageiEukaryotaAlveolataApicomplexaAconoidasidaHaemosporidaPlasmodiidaePlasmodiumPlasmodium (Laverania)
Proteomesi
  • UP000001450 Componenti: Chromosome 7

Organism-specific databases

EuPathDBiPlasmoDB:PF3D7_0725000

Subcellular locationi

GO - Cellular componenti

  • nucleus Source: GeneDB

PTM / Processingi

Proteomic databases

PRIDEiQ8IBK1

Interactioni

Protein-protein interaction databases

IntActiQ8IBK1, 7 interactors

Structurei

3D structure databases

ProteinModelPortaliQ8IBK1
SMRiQ8IBK1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 99XPGNInterPro annotationAdd BLAST99
Domaini142 – 210XPGIInterPro annotationAdd BLAST69

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili288 – 308Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

InParanoidiQ8IBK1
KOiK10746
PhylomeDBiQ8IBK1

Family and domain databases

InterProiView protein in InterPro
IPR036279 5-3_exonuclease_C_sf
IPR032641 Exo1
IPR029060 PIN-like_dom_sf
IPR006086 XPG-I_dom
IPR006084 XPG/Rad2
IPR006085 XPG_DNA_repair_N
PANTHERiPTHR11081 PTHR11081, 2 hits
PTHR11081:SF8 PTHR11081:SF8, 2 hits
PfamiView protein in Pfam
PF00867 XPG_I, 1 hit
PF00752 XPG_N, 1 hit
PRINTSiPR00853 XPGRADSUPER
SMARTiView protein in SMART
SM00484 XPGI, 1 hit
SM00485 XPGN, 1 hit
SUPFAMiSSF47807 SSF47807, 1 hit
SSF88723 SSF88723, 1 hit

Sequencei

Sequence statusi: Complete.

Q8IBK1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGISNLLQFL KPIIKNSHIS KYKNEVVGVD IMCWIHRGLI SCAYDIVTDQ
60 70 80 90 100
YNDSYLNFIE KMLVPIYNHN IKVVFVFDGE ELPEKKKENM IRKNRREKAK
110 120 130 140 150
MELQEIISKV KNPRTNEMVL KKCIQAISVS KEIIDSVKEF CRKKNIDYII
160 170 180 190 200
SPYEADAQLS YLCRMGFISC AISEDSDLLV YGCPRVLYKL KNTGECNEIS
210 220 230 240 250
LMPINDLIDW NVINKIKNPL SNSYNEFYIT PIKKLQNSDD YDSDISLDEE
260 270 280 290 300
TSVECINNDS YVQNNNEFIN ISKKTKSIVN SNNNNKKKKK KKNKNKKKTN
310 320 330 340 350
KKKNMQKSKC DNIIKQYIQQ FDWPEELFKL QYFNIDMFLT MCVLSGCDYS
360 370 380 390 400
NDFHITGMGI KTAYNLIFQH KNIENIFHFL ISNDRWRNKI PENLNTFDKL
410 420 430 440 450
MNTFQKIKNA FLNHQVYDFI LRKNIPINES FKSSFVNKNS HFIIQQITEA
460 470 480 490 500
SLLYDPLLKI DNCLNIYPQL NDIPLSSPQI QDDDYNKNDD THNKGGDDNI
510 520 530 540 550
KINHDTHNKG GDDNFKINHD THNKGGDDNF KINHDTHNKG GDNFNINTVN
560 570 580 590 600
CSFYNNHQIY TQSSKSPSFE NIFKDFTSEC FEYLEISPPA FIDPQNNNIQ
610 620 630 640 650
NNSKNEYFHN IITQEQVIQQ ADVCPPLIHK DTNISNEIND EYHHLISDIT
660 670 680 690 700
YNEYKNKTIE NCNERINKRK TDDCISSFNL KKKVKTTSAH TSSSNSQDNL
710 720 730 740 750
TIQHIEALDC NNQNVNDNEE KKNIYENSCN YDETFNSERV NILSMYDNNY
760 770 780 790 800
QMWEKKDDLL KNNNNSFHSN NIMETYNDHY INKTYDEHSN NKVNINICDD
810 820 830 840 850
ITTTNNDHNE EMLDEKKEFA QIKSAKNIYE NMKKNFFLFK TLNEDMNTPI
860 870 880 890 900
KSLNVKGKMN MQDNCEQDDK VGNLKSDKMT EQNEKCDNIS NEKCDNILND
910 920 930 940 950
KCDNILNDKC DNILNDKCDN ISNEKCDNIL NDKCDNISNE KCDNVPNDIC
960 970 980 990 1000
DYVPNDICDY VPNNTPNLIT NCIQNKMTTL LQITEENSLN SYNKNDTSFN
1010 1020 1030 1040 1050
KDFHINKTYL NKKDTEINFQ INEKKKNDLL RNPLEESRKS SLTSYKNKTP
1060 1070 1080 1090 1100
SKNVNSKSQL RITSFFKRID KKTNENHNMH NSTQKICNDH NNNPNDNIQN
1110 1120 1130 1140 1150
DKFYNNIYMN SPINYSVEYS EEDYINSFND NYSDMKTFQK LKKKTKRNIK
1160 1170 1180 1190 1200
NTPQSYSIKD HFAVSLQSQD KNDKLSFTNY NSLEKDIFLN QGEKELQFNH
1210 1220 1230 1240 1250
NSINKEKNQN KHLQISSLTN HDNIIMNNHT SNLNTQQNEK QSSNHNTIII
1260 1270 1280 1290 1300
HSNNHQPNFT NENVKSNNVS TEQDTYNKHI TVLKSTEKLQ NQSIEKNKET
1310 1320 1330 1340
SQKINVEYIL QNLNYNYQPK NQKINTFDYF KEKENVNHCN PYIDHNL
Length:1,347
Mass (Da):157,929
Last modified:March 1, 2003 - v1
Checksum:iEA51A65CD219F778
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL844506 Genomic DNA Translation: CAD50999.1
RefSeqiXP_001349153.1, XM_001349117.1

Genome annotation databases

EnsemblProtistsiCAD50999; CAD50999; PF3D7_0725000
GeneDBiPF3D7_0725000.1:pep
GeneIDi2655158
KEGGipfa:PF07_0105

Similar proteinsi

Entry informationi

Entry nameiQ8IBK1_PLAF7
AccessioniPrimary (citable) accession number: Q8IBK1
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: May 23, 2018
This is version 92 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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