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Protein
Submitted name:

Variable region-containing chitin-binding protein 3

Gene

VCBP3

Organism
Branchiostoma floridae (Florida lancelet) (Amphioxus)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Protein family/group databases

MEROPSiI43.001.

Names & Taxonomyi

Protein namesi
Submitted name:
Variable region-containing chitin-binding protein 3Imported
Gene namesi
Name:VCBP3Imported
OrganismiBranchiostoma floridae (Florida lancelet) (Amphioxus)Imported
Taxonomic identifieri7739 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCephalochordataBranchiostomidaeBranchiostoma

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1616Sequence analysisAdd
BLAST
Chaini17 – 334318Sequence analysisPRO_5004308504Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi41 ↔ 124Combined sources
Disulfide bondi175 ↔ 247Combined sources
Disulfide bondi177 ↔ 180Combined sources

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1XT5X-ray1.15A16-150[»]
2FBOX-ray1.85J18-267[»]
ProteinModelPortaliQ8I9N0.
SMRiQ8I9N0. Positions 18-267.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ8I9N0.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini17 – 143127Ig-like (immunoglobulin-like)InterPro annotationAdd
BLAST
Domaini151 – 263113Ig-like (immunoglobulin-like)InterPro annotationAdd
BLAST
Domaini271 – 33161Chitin-binding type-2InterPro annotationAdd
BLAST

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

HOVERGENiHBG071226.

Family and domain databases

Gene3Di2.170.140.10. 1 hit.
2.60.40.10. 2 hits.
InterProiIPR002557. Chitin-bd_dom.
IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003599. Ig_sub.
IPR013106. Ig_V-set.
[Graphical view]
PfamiPF01607. CBM_14. 1 hit.
PF07686. V-set. 1 hit.
[Graphical view]
SMARTiSM00494. ChtBD2. 1 hit.
SM00409. IG. 2 hits.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 2 hits.
SSF57625. SSF57625. 1 hit.
PROSITEiPS50940. CHIT_BIND_II. 1 hit.
PS50835. IG_LIKE. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8I9N0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQMFLLVSVC LGMAYGQSIM TVRTTHTEVE VHAGGTVELP CSYQLANDTQ
60 70 80 90 100
PPVISWLKGA SPDRSTKVFK GNYNWQGEGL GFVESDSYKE SFGDFLGRAS
110 120 130 140 150
VANLAAPTLR LTHVHPQDGG RYWCQVAQWS IRTEFGLDAK SVVLKVTGHT
160 170 180 190 200
PSNNVHVSTA EVVQVDEGND ITMTCPCTDC ANANVTWYTG PTFFENYETG
210 220 230 240 250
TYQPLANKNQ FGITWFSSEI AGRASFSGAR NLVIRAAKIT DAGRVWCELA
260 270 280 290 300
TGQGELDADR SSTILKVQLE PFTCDGKPTG LYADPTACDY YYQCIPGYPP
310 320 330
LHRPCGYAGM VFNEEMQYCD WDINVPPPCG SKPV
Length:334
Mass (Da):36,642
Last modified:March 1, 2003 - v1
Checksum:iAC2E523F55251ECB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF520474 mRNA. Translation: AAN62850.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF520474 mRNA. Translation: AAN62850.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1XT5X-ray1.15A16-150[»]
2FBOX-ray1.85J18-267[»]
ProteinModelPortaliQ8I9N0.
SMRiQ8I9N0. Positions 18-267.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

MEROPSiI43.001.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

HOVERGENiHBG071226.

Miscellaneous databases

EvolutionaryTraceiQ8I9N0.

Family and domain databases

Gene3Di2.170.140.10. 1 hit.
2.60.40.10. 2 hits.
InterProiIPR002557. Chitin-bd_dom.
IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003599. Ig_sub.
IPR013106. Ig_V-set.
[Graphical view]
PfamiPF01607. CBM_14. 1 hit.
PF07686. V-set. 1 hit.
[Graphical view]
SMARTiSM00494. ChtBD2. 1 hit.
SM00409. IG. 2 hits.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 2 hits.
SSF57625. SSF57625. 1 hit.
PROSITEiPS50940. CHIT_BIND_II. 1 hit.
PS50835. IG_LIKE. 2 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Identification of diversified genes that contain immunoglobulin-like variable regions in a protochordate."
    Cannon J.P., Haire R.N., Litman G.W.
    Nat. Immunol. 3:1200-1207(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  2. "Ancient evolutionary origin of diversified variable regions demonstrated by crystal structures of an immune-type receptor in amphioxus."
    Hernandez Prada J.A., Haire R.N., Allaire M., Jakoncic J., Stojanoff V., Cannon J.P., Litman G.W., Ostrov D.A.
    Nat. Immunol. 7:875-882(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (1.15 ANGSTROMS) OF 16-150, DISULFIDE BONDS.

Entry informationi

Entry nameiQ8I9N0_BRAFL
AccessioniPrimary (citable) accession number: Q8I9N0
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: March 16, 2016
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.