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Protein

Tachykinin-1

Gene
N/A
Organism
Octopus vulgaris (Common octopus)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles.1 Publication

GO - Biological processi

Keywordsi

Molecular functionNeuropeptide

Names & Taxonomyi

Protein namesi
Recommended name:
Tachykinin-1
Alternative name(s):
OctTK-I
Tachykinin I
OrganismiOctopus vulgaris (Common octopus)
Taxonomic identifieri6645 [NCBI]
Taxonomic lineageiEukaryotaMetazoaLophotrochozoaMolluscaCephalopodaColeoideaNeocoleoideaOctopodiformesOctopodaIncirrataOctopodidaeOctopus

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 221 PublicationSequence analysisAdd BLAST22
PropeptideiPRO_000003351623 – 371 PublicationAdd BLAST15
PeptideiPRO_000003351738 – 49Tachykinin-1Add BLAST12
PropeptideiPRO_000003351852 – 871 PublicationAdd BLAST36

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei49Methionine amide1 Publication1

Keywords - PTMi

Amidation

Expressioni

Tissue specificityi

Expressed in the posterior salivary gland and more specifically in the mucus-secreting gland cells.1 Publication

Family & Domainsi

Sequence similaritiesi

Belongs to the tachykinin family.1 Publication

Keywords - Domaini

Signal

Family and domain databases

InterProiView protein in InterPro
IPR013055. Tachy_Neuro_lke_CS.
PROSITEiView protein in PROSITE
PS00267. TACHYKININ. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q8I6S3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIRVGLILCC IFIAGVFEAS SADDMLTAHN LIKRSEVKPP SSSEFIGLMG
60 70 80
RSEELTRRLI QHPGSMSETS KRGPPKKVSR RPYILKK
Length:87
Mass (Da):9,699
Last modified:March 1, 2003 - v1
Checksum:iE81447859911840C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB085916 mRNA. Translation: BAC53870.1.

Similar proteinsi

Entry informationi

Entry nameiTKN1_OCTVU
AccessioniPrimary (citable) accession number: Q8I6S3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 31, 2004
Last sequence update: March 1, 2003
Last modified: April 12, 2017
This is version 34 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

Documents

  1. SIMILARITY comments
    Index of protein domains and families