Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q8I6L9

- Q8I6L9_TRYCR

UniProt

Q8I6L9 - Q8I6L9_TRYCR

Protein
Submitted name:

Prostaglandin F2a synthase

Gene

TcPGFS

Organism
Trypanosoma cruzi
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 30 (01 Oct 2014)
      Sequence version 1 (01 Mar 2003)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei61 – 611FMN; via amide nitrogenImported
    Binding sitei103 – 1031FMNImported
    Binding sitei195 – 1951FMNImported
    Binding sitei249 – 2491FMNImported

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi26 – 283FMNImported
    Nucleotide bindingi313 – 3153FMNImported
    Nucleotide bindingi336 – 3372FMNImported

    GO - Molecular functioni

    1. FMN binding Source: InterPro
    2. oxidoreductase activity Source: InterPro

    Keywords - Ligandi

    Flavoprotein, FMNImported, Nucleotide-bindingImported

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Prostaglandin F2a synthaseImported
    Gene namesi
    Name:TcPGFSImported
    OrganismiTrypanosoma cruziImported
    Taxonomic identifieri5693 [NCBI]
    Taxonomic lineageiEukaryotaEuglenozoaKinetoplastidaTrypanosomatidaeTrypanosomaSchizotrypanum

    Structurei

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    3ATYX-ray1.70A/B1-379[»]
    3ATZX-ray2.04A/B/C/D1-379[»]
    ProteinModelPortaliQ8I6L9.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Family and domain databases

    Gene3Di3.20.20.70. 1 hit.
    InterProiIPR013785. Aldolase_TIM.
    IPR001155. OxRdtase_FMN_N.
    [Graphical view]
    PfamiPF00724. Oxidored_FMN. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q8I6L9-1 [UniParc]FASTAAdd to Basket

    « Hide

    MATFPELLRP LKLGRYTLRN RIIMAPLTRC QATEDDHVPR TESMLKYYED    50
    RASAGLIIAE ATMVQPNYTG FLTEPGIYSD AQIEEWRKIV DAVHKKGGLI 100
    FLQLIHAGRA GIPEKILQQS KSDQDPLAGR LLAASAIPIK DHRIPAYFAA 150
    SGEKETYGVP EELTDDEVRD GIIPLFVEGA KNAIFKAGFD GVEIHGANGY 200
    LLDAFFRESS NKRQSGPYAG TTIDTRCQLI YDVTKSVCDA VGSDRVGLRI 250
    SPLNGVHGMI DSNPEALTKH LCKKIEPLSL AYLHYLRGDM VNQQIGDVVA 300
    WVRGSYSGVK ISNLRYDFEE ADQQIREGKV DAVAFGAKFI ANPDLVERAQ 350
    QNWPLNEPRP ETYYTRTAVG YNDYPTYNK 379
    Length:379
    Mass (Da):42,261
    Last modified:March 1, 2003 - v1
    Checksum:i4EEC57419ACAF8CE
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB075599 mRNA. Translation: BAC24024.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB075599 mRNA. Translation: BAC24024.1 .

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    3ATY X-ray 1.70 A/B 1-379 [» ]
    3ATZ X-ray 2.04 A/B/C/D 1-379 [» ]
    ProteinModelPortali Q8I6L9.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    Gene3Di 3.20.20.70. 1 hit.
    InterProi IPR013785. Aldolase_TIM.
    IPR001155. OxRdtase_FMN_N.
    [Graphical view ]
    Pfami PF00724. Oxidored_FMN. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE.
    2. "Structural insight into the stereoselective production of PGF2? by Old Yellow Enzyme from Trypanosoma cruzi."
      Okamoto N., Yamaguchi K., Mizohata E., Tokuoka K., Uchiyama N., Sugiyama S., Matsumura H., Inaka K., Urade Y., Inoue T.
      J. Biochem. 150:563-568(2011) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (1.70 ANGSTROMS) IN COMPLEX WITH FMN.

    Entry informationi

    Entry nameiQ8I6L9_TRYCR
    AccessioniPrimary (citable) accession number: Q8I6L9
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 1, 2003
    Last sequence update: March 1, 2003
    Last modified: October 1, 2014
    This is version 30 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    3D-structureImported

    External Data

    Dasty 3