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Q8I6L9 (Q8I6L9_TRYCR) Unreviewed, UniProtKB/TrEMBL

Last modified December 11, 2013. Version 28. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein names
Gene names
Name:TcPGFS EMBL BAC24024.1
OrganismTrypanosoma cruzi EMBL BAC24024.1
Taxonomic identifier5693 [NCBI]
Taxonomic lineageEukaryotaEuglenozoaKinetoplastidaTrypanosomatidaeTrypanosomaSchizotrypanum

Protein attributes

Sequence length379 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding26 – 283FMN PDB 3ATY PDB 3ATZ
Nucleotide binding313 – 3153FMN PDB 3ATY PDB 3ATZ
Nucleotide binding336 – 3372FMN PDB 3ATY PDB 3ATZ
Region195 – 1984p-hydroxybenzaldehyde binding PDB 3ATZ

Sites

Binding site611FMN; via amide nitrogen PDB 3ATY PDB 3ATZ
Binding site711p-hydroxybenzaldehyde PDB 3ATZ
Binding site1031FMN PDB 3ATY PDB 3ATZ
Binding site1951FMN PDB 3ATY PDB 3ATZ
Binding site2491FMN PDB 3ATY PDB 3ATZ
Binding site3641p-hydroxybenzaldehyde PDB 3ATZ

Sequences

Sequence LengthMass (Da)Tools
Q8I6L9 [UniParc].

Last modified March 1, 2003. Version 1.
Checksum: 4EEC57419ACAF8CE

FASTA37942,261
        10         20         30         40         50         60 
MATFPELLRP LKLGRYTLRN RIIMAPLTRC QATEDDHVPR TESMLKYYED RASAGLIIAE 

        70         80         90        100        110        120 
ATMVQPNYTG FLTEPGIYSD AQIEEWRKIV DAVHKKGGLI FLQLIHAGRA GIPEKILQQS 

       130        140        150        160        170        180 
KSDQDPLAGR LLAASAIPIK DHRIPAYFAA SGEKETYGVP EELTDDEVRD GIIPLFVEGA 

       190        200        210        220        230        240 
KNAIFKAGFD GVEIHGANGY LLDAFFRESS NKRQSGPYAG TTIDTRCQLI YDVTKSVCDA 

       250        260        270        280        290        300 
VGSDRVGLRI SPLNGVHGMI DSNPEALTKH LCKKIEPLSL AYLHYLRGDM VNQQIGDVVA 

       310        320        330        340        350        360 
WVRGSYSGVK ISNLRYDFEE ADQQIREGKV DAVAFGAKFI ANPDLVERAQ QNWPLNEPRP 

       370 
ETYYTRTAVG YNDYPTYNK 

« Hide

References

[1]"A key role for old yellow enzyme in the metabolism of drugs by Trypanosoma cruzi."
Kubata B.K., Kabututu Z., Nozaki T., Munday C.J., Fukuzumi S., Ohkubo K., Lazarus M., Maruyama T., Martin S.K., Duszenko M., Urade Y.
J. Exp. Med. 196:1241-1251(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
[2]"Structural insight into the stereoselective production of PGF2? by Old Yellow Enzyme from Trypanosoma cruzi."
Okamoto N., Yamaguchi K., Mizohata E., Tokuoka K., Uchiyama N., Sugiyama S., Matsumura H., Inaka K., Urade Y., Inoue T.
J. Biochem. 150:563-568(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (1.70 ANGSTROMS) IN COMPLEX WITH FMN AND P-HYDROXYBENZALDEHYDE.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AB075599 mRNA. Translation: BAC24024.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
3ATYX-ray1.70A/B1-379[»]
3ATZX-ray2.04A/B/C/D1-379[»]
ProteinModelPortalQ8I6L9.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D3.20.20.70. 1 hit.
InterProIPR013785. Aldolase_TIM.
IPR001155. OxRdtase_FMN_N.
[Graphical view]
PfamPF00724. Oxidored_FMN. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ8I6L9_TRYCR
AccessionPrimary (citable) accession number: Q8I6L9
Entry history
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: December 11, 2013
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)