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Protein
Submitted name:

Ubiquitin conjugating enzyme E2, putative

Gene

PF3D7_1203900

Organism
Plasmodium falciparum (isolate 3D7)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei85Glycyl thioester intermediatePROSITE-ProRule annotation1

GO - Molecular functioni

  • ATP binding Source: UniProtKB-UniRule
  • ligase activity Source: UniProtKB-KW
  • ubiquitin-protein transferase activity Source: GeneDB

GO - Biological processi

  • cellular protein modification process Source: GeneDB

Keywordsi

Molecular functionLigaseImported
Biological processUbl conjugation pathwayUniRule annotationSAAS annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-PFA-8866652. Synthesis of active ubiquitin: roles of E1 and E2 enzymes.

Protein family/group databases

TCDBi3.A.16.1.3. the endoplasmic reticular retrotranslocon (er-rt) family.

Names & Taxonomyi

Protein namesi
Submitted name:
Ubiquitin conjugating enzyme E2, putativeImported (EC:6.3.2.19Imported)
Submitted name:
Ubiquitin-conjugating enzyme E2Imported
Gene namesi
ORF Names:PF3D7_1203900Imported, PFL0190wImported
OrganismiPlasmodium falciparum (isolate 3D7)Imported
Taxonomic identifieri36329 [NCBI]
Taxonomic lineageiEukaryotaAlveolataApicomplexaAconoidasidaHaemosporidaPlasmodiidaePlasmodiumPlasmodium (Laverania)
Proteomesi
  • UP000001450 Componenti: Chromosome 12

Organism-specific databases

EuPathDBiPlasmoDB:PF3D7_1203900.

Subcellular locationi

GO - Cellular componenti

  • cytoplasm Source: GeneDB

Interactioni

Protein-protein interaction databases

IntActiQ8I607. 3 interactors.
MINTiMINT-1555998.

Structurei

3D structure databases

SMRiQ8I607.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 136UBIQUITIN_CONJUGAT_2InterPro annotationAdd BLAST133

Sequence similaritiesi

Belongs to the ubiquitin-conjugating enzyme family.PROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

HOGENOMiHOG000233455.
InParanoidiQ8I607.
KOiK06689.
OMAiIAHIYKQ.

Family and domain databases

CDDicd00195. UBCc. 1 hit.
Gene3Di3.10.110.10. 1 hit.
InterProiView protein in InterPro
IPR000608. UBQ-conjugat_E2.
IPR023313. UBQ-conjugating_AS.
IPR016135. UBQ-conjugating_enzyme/RWD.
PfamiView protein in Pfam
PF00179. UQ_con. 1 hit.
SUPFAMiSSF54495. SSF54495. 1 hit.
PROSITEiView protein in PROSITE
PS00183. UBIQUITIN_CONJUGAT_1. 1 hit.
PS50127. UBIQUITIN_CONJUGAT_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8I607-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALKRITKEL QDLNKDPPTN CSAGPIGDDL FFWQATIMGP GDSPYENGVY
60 70 80 90 100
FLNIKFPPDY PFKPPKIIFT TKIYHPNINT AGAICLDILK DQWSPALTIS
110 120 130 140
KVLLSISSLL TDPNADDPLV PEIAHVYKTD RTKYHQTAKA WTQKYAQ
Length:147
Mass (Da):16,539
Last modified:March 1, 2003 - v1
Checksum:i233FBD5A8481B085
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014188 Genomic DNA. Translation: AAN36127.1.
LN999947 Genomic DNA. Translation: CZT99202.1.
RefSeqiXP_001350447.1. XM_001350411.1.

Genome annotation databases

EnsemblProtistsiCZT99202; CZT99202; PF3D7_1203900.
GeneDBiPF3D7_1203900.1:pep.
GeneIDi811091.
KEGGipfa:PFL0190w.

Similar proteinsi

Entry informationi

Entry nameiQ8I607_PLAF7
AccessioniPrimary (citable) accession number: Q8I607
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: December 20, 2017
This is version 112 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported