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Protein
Submitted name:

ATP-dependent RNA helicase, putative

Gene

PF3D7_1227100

Organism
Plasmodium falciparum (isolate 3D7)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

  • ATP binding Source: UniProtKB-KW
  • ATP-dependent RNA helicase activity Source: GeneDB
  • RNA binding Source: GeneDB

GO - Biological processi

  • RNA metabolic process Source: GeneDB
  • RNA secondary structure unwinding Source: GO_Central

Keywordsi

Molecular functionHelicaseUniRule annotationImported, Hydrolase
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
ATP-dependent RNA helicase, putativeImported
Submitted name:
DNA helicase 60Imported (EC:3.6.4.12Imported)
Gene namesi
ORF Names:PF3D7_1227100Imported, PFL1310cImported
OrganismiPlasmodium falciparum (isolate 3D7)Imported
Taxonomic identifieri36329 [NCBI]
Taxonomic lineageiEukaryotaAlveolataApicomplexaAconoidasidaHaemosporidaPlasmodiidaePlasmodiumPlasmodium (Laverania)
Proteomesi
  • UP000001450 Componenti: Chromosome 12

Organism-specific databases

EuPathDBiPlasmoDB:PF3D7_1227100.

Subcellular locationi

GO - Cellular componenti

Structurei

3D structure databases

SMRiQ8I5E7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini288 – 315Q_MOTIFInterPro annotationAdd BLAST28
Domaini318 – 560Helicase ATP-bindingInterPro annotationAdd BLAST243
Domaini586 – 739Helicase C-terminalInterPro annotationAdd BLAST154

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili361 – 381Sequence analysisAdd BLAST21
Coiled coili385 – 405Sequence analysisAdd BLAST21

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi288 – 315Q motifPROSITE-ProRule annotationAdd BLAST28

Sequence similaritiesi

Belongs to the DEAD box helicase family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

HOGENOMiHOG000268804.
InParanoidiQ8I5E7.
KOiK12823.
OMAiDNHVDNH.

Family and domain databases

CDDicd00079. HELICc. 1 hit.
InterProiView protein in InterPro
IPR011545. DEAD/DEAH_box_helicase_dom.
IPR014001. Helicase_ATP-bd.
IPR001650. Helicase_C.
IPR027417. P-loop_NTPase.
IPR000629. RNA-helicase_DEAD-box_CS.
IPR014014. RNA_helicase_DEAD_Q_motif.
PfamiView protein in Pfam
PF00270. DEAD. 1 hit.
PF00271. Helicase_C. 1 hit.
SMARTiView protein in SMART
SM00487. DEXDc. 1 hit.
SM00490. HELICc. 1 hit.
SUPFAMiSSF52540. SSF52540. 3 hits.
PROSITEiView protein in PROSITE
PS00039. DEAD_ATP_HELICASE. 1 hit.
PS51192. HELICASE_ATP_BIND_1. 1 hit.
PS51194. HELICASE_CTER. 1 hit.
PS51195. Q_MOTIF. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8I5E7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRRNLLKLTS INCKKNDYVS LSNNFFLIKN RSYKYITVRN KIGRNVFNEK
60 70 80 90 100
DNCAILNRGQ THVVGIKKNI CTENKVKQQD GEFYMNQRVP DDMDNDMDNN
110 120 130 140 150
VDNDMDNNVD NHVDNHVDNH VDNHVDNHMD NHINNHTHKN VHDDTSYDNN
160 170 180 190 200
SFDRYQRKRD EIGENGFVQN RRYENYEKRK QSKTNYSYDN DYNQGSRNKR
210 220 230 240 250
NMSYPDRYEE LGSHLKDIEW DNVKYKMERQ NLYNNNYNKC NDQNNNQNSN
260 270 280 290 300
DNLNNEQTNC LSKEDIQNEL KKNNIYINKD GIIHNIINKF SDVCFHESIL
310 320 330 340 350
NYLNNKFSEP TAIQKITWPI ALSGKDLIGV AETGSGKTLA FVLPCFMHIL
360 370 380 390 400
KHKEIIQNNN NNKQTNQNNN LQQEQEGKTN NHHIINNYNE NNDNNENNHN
410 420 430 440 450
NNNNNNNNNN NSYDYDYDIN SSERASDTYG LILLPTRELC LQVLDEIKSF
460 470 480 490 500
EKNLPIKSVA VYGGVPKYYQ INNLKKGADI IVATPGRLLD FLENGNINLL
510 520 530 540 550
KCIYVVIDEA DRLLDMGFEK QLRKIMTQVN KNKQLLFLTA TWPEQVRKLA
560 570 580 590 600
YDFCSYDPVK IQIGKNELTA NKNIEQNVII SSSIDMKKKL LDWLKENYEN
610 620 630 640 650
NKILIFCDTK RNCDNLCKEL RYHQYNALSI HGDKQQRERD RILNNYKTDR
660 670 680 690 700
CNILVATDVA SRGLDIKNIS VVINYDIPNT IEDYIHRIGR TGRAGKKGKS
710 720 730 740
ILFFSYDYYM PQKLKFAKEL IKLLNKTNQT VPPQLKEIAY SR
Length:742
Mass (Da):87,020
Last modified:March 1, 2003 - v1
Checksum:iDA4AF4120205912B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014848 Genomic DNA. Translation: AAN36348.1.
LN999947 Genomic DNA. Translation: CZT99430.1.
RefSeqiXP_001350668.1. XM_001350632.1.

Genome annotation databases

EnsemblProtistsiCZT99430; CZT99430; PF3D7_1227100.
GeneDBiPF3D7_1227100.1:pep.
GeneIDi811314.
KEGGipfa:PFL1310c.

Similar proteinsi

Entry informationi

Entry nameiQ8I5E7_PLAF7
AccessioniPrimary (citable) accession number: Q8I5E7
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: December 20, 2017
This is version 114 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported