Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q8I4D9

- Q8I4D9_CAEEL

UniProt

Q8I4D9 - Q8I4D9_CAEEL

Protein
Submitted name:

Protein UNC-25, isoform c

Gene

unc-25

Organism
Caenorhabditis elegans
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 80 (01 Oct 2014)
      Sequence version 1 (01 Mar 2003)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Cofactori

    Pyridoxal phosphate.UniRule annotation

    GO - Molecular functioni

    1. glutamate decarboxylase activity Source: WormBase
    2. pyridoxal phosphate binding Source: WormBase

    GO - Biological processi

    1. gamma-aminobutyric acid biosynthetic process Source: WormBase
    2. synaptic transmission, GABAergic Source: WormBase

    Keywords - Molecular functioni

    LyaseUniRule annotation

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotation

    Enzyme and pathway databases

    ReactomeiREACT_183019. GABA synthesis, release, reuptake and degradation.
    REACT_183178. GABA synthesis.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Protein UNC-25, isoform cImported
    Gene namesi
    Name:unc-25Imported
    ORF Names:CELE_Y37D8A.23Imported, Y37D8A.23Imported
    OrganismiCaenorhabditis elegansImported
    Taxonomic identifieri6239 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
    ProteomesiUP000001940: Chromosome III

    Organism-specific databases

    WormBaseiY37D8A.23c; CE32012; WBGene00006762; unc-25.

    Subcellular locationi

    GO - Cellular componenti

    1. axon Source: WormBase
    2. inhibitory synapse Source: WormBase
    3. neuronal cell body Source: WormBase
    4. synaptic vesicle Source: WormBase

    PTM / Processingi

    Proteomic databases

    PaxDbiQ8I4D9.
    PRIDEiQ8I4D9.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8I4D9.
    SMRiQ8I4D9. Positions 12-425.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the group II decarboxylase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0076.
    GeneTreeiENSGT00730000110441.
    HOGENOMiHOG000005382.
    KOiK01580.

    Family and domain databases

    Gene3Di3.40.640.10. 1 hit.
    3.90.1150.10. 1 hit.
    InterProiIPR002129. PyrdxlP-dep_de-COase.
    IPR015424. PyrdxlP-dep_Trfase.
    IPR015421. PyrdxlP-dep_Trfase_major_sub1.
    IPR015422. PyrdxlP-dep_Trfase_major_sub2.
    [Graphical view]
    PfamiPF00282. Pyridoxal_deC. 1 hit.
    [Graphical view]
    SUPFAMiSSF53383. SSF53383. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q8I4D9-1 [UniParc]FASTAAdd to Basket

    « Hide

    MLCSRILLRK SCEDVLRLGV RTGHPRFFNQ ISCGLDLVSM AGEWLTATAN    50
    TNMFTYEIAP VFILMEKSVM ARMWEAVGWD PEKADGIFAP GGAIANLYAM 100
    NAARHQLWPR SKHLGMKDIP TLCCFTSEDS HYSIKSASAV LGIGADYCFN 150
    IPTDKNGKMI PEALEAKIIE CKKEGLTPFF ACCTAGSTVY GAFDPLERVA 200
    NICERHKLWF HVDAAWGGGM LLSPEHRYKL AGIERANSVT WNPHKLMGAL 250
    LQCSACLFRQ DGLLFQCNQM SADYLFQQDK PYDVSFDTGD KAIQCGRHND 300
    VFKLWLMWKS KGMEGYRQQI NKLMDLANYF TRRIKETEGF ELIIENPEFL 350
    NICFWYVPSK IRNLEPAEMR ARLEKIAPKI KAGMMQRGTT MVGYQPDKQR 400
    PNFFRMIISN QAITREDLDF LIKEIVDIGE SLE 433
    Length:433
    Mass (Da):49,233
    Last modified:March 1, 2003 - v1
    Checksum:iF8267E0254CB8F60
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL032626 Genomic DNA. Translation: CAD45606.2.
    RefSeqiNP_001022832.1. NM_001027661.2.
    UniGeneiCel.7826.

    Genome annotation databases

    EnsemblMetazoaiY37D8A.23c; Y37D8A.23c; WBGene00006762.
    GeneIDi176713.
    KEGGicel:CELE_Y37D8A.23.
    UCSCiY37D8A.23a. c. elegans.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL032626 Genomic DNA. Translation: CAD45606.2 .
    RefSeqi NP_001022832.1. NM_001027661.2.
    UniGenei Cel.7826.

    3D structure databases

    ProteinModelPortali Q8I4D9.
    SMRi Q8I4D9. Positions 12-425.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PaxDbi Q8I4D9.
    PRIDEi Q8I4D9.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblMetazoai Y37D8A.23c ; Y37D8A.23c ; WBGene00006762 .
    GeneIDi 176713.
    KEGGi cel:CELE_Y37D8A.23.
    UCSCi Y37D8A.23a. c. elegans.

    Organism-specific databases

    CTDi 176713.
    WormBasei Y37D8A.23c ; CE32012 ; WBGene00006762 ; unc-25.

    Phylogenomic databases

    eggNOGi COG0076.
    GeneTreei ENSGT00730000110441.
    HOGENOMi HOG000005382.
    KOi K01580.

    Enzyme and pathway databases

    Reactomei REACT_183019. GABA synthesis, release, reuptake and degradation.
    REACT_183178. GABA synthesis.

    Miscellaneous databases

    NextBioi 893696.

    Family and domain databases

    Gene3Di 3.40.640.10. 1 hit.
    3.90.1150.10. 1 hit.
    InterProi IPR002129. PyrdxlP-dep_de-COase.
    IPR015424. PyrdxlP-dep_Trfase.
    IPR015421. PyrdxlP-dep_Trfase_major_sub1.
    IPR015422. PyrdxlP-dep_Trfase_major_sub2.
    [Graphical view ]
    Pfami PF00282. Pyridoxal_deC. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53383. SSF53383. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
      The C. elegans sequencing consortium
      Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Bristol N2Imported.

    Entry informationi

    Entry nameiQ8I4D9_CAEEL
    AccessioniPrimary (citable) accession number: Q8I4D9
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 1, 2003
    Last sequence update: March 1, 2003
    Last modified: October 1, 2014
    This is version 80 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3