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Protein
Submitted name:

Pre-mRNA-processing ATP-dependent RNA helicase PRP5, putative

Gene

PF3D7_0508700

Organism
Plasmodium falciparum (isolate 3D7)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  • ATP binding Source: InterPro
  • ATP-dependent RNA helicase activity Source: GeneDB
  • nucleic acid binding Source: InterPro

GO - Biological processi

Keywordsi

Molecular functionHelicaseImported, Hydrolase
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Pre-mRNA-processing ATP-dependent RNA helicase PRP5, putativeImported (EC:3.6.4.13Imported)
Gene namesi
ORF Names:PF3D7_0508700Imported
OrganismiPlasmodium falciparum (isolate 3D7)Imported
Taxonomic identifieri36329 [NCBI]
Taxonomic lineageiEukaryotaAlveolataApicomplexaAconoidasidaHaemosporidaPlasmodiidaePlasmodiumPlasmodium (Laverania)
Proteomesi
  • UP000001450 Componenti: Chromosome 5

Organism-specific databases

EuPathDBiPlasmoDB:PF3D7_0508700.

Subcellular locationi

GO - Cellular componenti

Interactioni

Protein-protein interaction databases

IntActiQ8I416. 6 interactors.
MINTiMINT-1560531.

Structurei

3D structure databases

ProteinModelPortaliQ8I416.
SMRiQ8I416.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini723 – 751Q_MOTIFInterPro annotationAdd BLAST29
Domaini754 – 932Helicase ATP-bindingInterPro annotationAdd BLAST179
Domaini943 – 1110Helicase C-terminalInterPro annotationAdd BLAST168

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili64 – 84Sequence analysisAdd BLAST21
Coiled coili168 – 196Sequence analysisAdd BLAST29
Coiled coili543 – 563Sequence analysisAdd BLAST21

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi723 – 751Q motifPROSITE-ProRule annotationAdd BLAST29

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

HOGENOMiHOG000284107.
InParanoidiQ8I416.
KOiK12811.
PhylomeDBiQ8I416.

Family and domain databases

CDDicd00079. HELICc. 1 hit.
InterProiView protein in InterPro
IPR011545. DEAD/DEAH_box_helicase_dom.
IPR014001. Helicase_ATP-bd.
IPR001650. Helicase_C.
IPR027417. P-loop_NTPase.
IPR000629. RNA-helicase_DEAD-box_CS.
IPR014014. RNA_helicase_DEAD_Q_motif.
PfamiView protein in Pfam
PF00270. DEAD. 1 hit.
PF00271. Helicase_C. 1 hit.
SMARTiView protein in SMART
SM00487. DEXDc. 1 hit.
SM00490. HELICc. 1 hit.
SUPFAMiSSF52540. SSF52540. 2 hits.
PROSITEiView protein in PROSITE
PS00039. DEAD_ATP_HELICASE. 1 hit.
PS51192. HELICASE_ATP_BIND_1. 1 hit.
PS51194. HELICASE_CTER. 1 hit.
PS51195. Q_MOTIF. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8I416-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYNIFNYIYK DSKEEKKNDK DKDMDIKVKK QDHDDSDDVL KRDNISSNKK
60 70 80 90 100
KDVERNTYYD NSYNEEEENK KKKKKRDSKK YSVDDSYNKT KNKIYNDHKT
110 120 130 140 150
DEYPSYAYKK KSSYHHVHRE KYPDEKRKKY YEHIGKKNKR RSYDYSSNYD
160 170 180 190 200
ESDFSSTSSY YNERNKKYYK YEDKKKKEKE KEKEKERKRK KRYHHTDDDQ
210 220 230 240 250
DHLESYSSSR SSSRSSINIK EKQKHKKLYS HEKERKRKKR YSNSANYSSY
260 270 280 290 300
DEETKERDKK KKSYHHDFVL DDKKKNYHNY ESDEETNKDE SNNNNNNNNN
310 320 330 340 350
NNNNNNKDSS SENLNKTHEQ REKSININKI SKENQEICEE NKKEIQKVKE
360 370 380 390 400
NMSNVKVITE NNNLSRLERL KLFARKIKKT NDTTNEKHTK FTLNTKVNKI
410 420 430 440 450
KNLNIFINDQ DDESDNSKEK EFDIKNENKI NVQNVDDNNH KDDTKKKIYE
460 470 480 490 500
NHKIKEDSNN TNDIHVVEIN NKNEDALDLF MKEIEQACEE EKKNVKKSIT
510 520 530 540 550
LDEIYTYDMN KQKYEPFINP KNNEEIKEYN AKVKGNNIQQ GNIHEKQDSN
560 570 580 590 600
VNTQEDLKKE NKNITKNTTN NNYSDNNNNN DDDDDDDDDD DVFHKLFVEE
610 620 630 640 650
LKKKTEEDMK RNEKDNMNES NLTDSKNKKQ NKGSDASFSS SDDTDDKLSS
660 670 680 690 700
NKSELNYEEN GMKKMNKKLL EVNHDEIDYI PIKKNIYVQV KEITNMKDSD
710 720 730 740 750
VDMFRKNNGN IIVRGKNCPR PVQYFYQCGL PSKILQILEK KNFKKMYNIQ
760 770 780 790 800
MQTIPALMCG RDVIAIAETG SGKTLSYLFP VIRHVLHQEP LRNNDGPISI
810 820 830 840 850
ILTPTRELSI QVKNEAKIYC KAVNIEILAV YGGSNIARQL KVLKKGVEIL
860 870 880 890 900
VGTPGRIIDI LTISNCKVTN LNRVSFVVLD EADRLLDLGF ESQIYNILRN
910 920 930 940 950
CRKDKQTAMI SATFPNYIQN MAKKLLYKPI EIIVGEKGKT NNNIYQFVEI
960 970 980 990 1000
IEESKKVFRL LKLLGEWIKY GLVLIFVNKQ IEADLLYLEL YKYDYNLLVL
1010 1020 1030 1040 1050
HGGQDQTDRQ FTLEKFKKEE NKVLIATSVM ARGIDIKNII LVINYQCPDH
1060 1070 1080 1090 1100
IEDYIHRIGR TGRSNNIGYA YTFILPNEYT KAYDIYNLLK NNIYYLNKTI
1110 1120 1130 1140 1150
DIPQDLENMI IEYTKINSIN EKQKGKNKNL GYKGKGYKFT PDEKSRHQID
1160 1170 1180 1190 1200
IALAKKELGL TQENDENEKL QVDDELGDNI EHNNNTNVCN LKNADQNKNY
1210 1220 1230 1240 1250
DKFEDVKESN IYPYTIHNSN NNMFEDKNSG ISKNMSKKNN TNEKKNTNQY
1260 1270 1280 1290 1300
TDITKVEQEI QRIKMNDTME LSLKAKKINE LMKTYNFLSL QENHDKFLKN
1310 1320 1330 1340 1350
AQYEEFDKIA EKEALKVTEH IKDEKEKKLI FNKTKEDIKK KLIQNKIQSD
1360 1370 1380 1390 1400
TMNESIQRNM LLSALRTKNM KKYSPYLPHT YITEDNNILE EFYINNYPQH
1410 1420 1430 1440 1450
VRLKISHKDV LAKIADMSGA TCQIKGQYSN PSQPNKQNFL LDTKQLHIEI
1460 1470 1480 1490
LAPTYNQIQI ARNELNSLLN NFMISCNIKA KRASTGWAPP
Length:1,490
Mass (Da):175,807
Last modified:March 1, 2003 - v1
Checksum:iE2E1637E0138C9FC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL844504 Genomic DNA. Translation: CAD51452.1.
RefSeqiXP_001351645.1. XM_001351609.1.

Genome annotation databases

EnsemblProtistsiCAD51452; CAD51452; PF3D7_0508700.
GeneDBiPF3D7_0508700.1:pep.
GeneIDi812854.
KEGGipfa:PFE0430w.

Similar proteinsi

Entry informationi

Entry nameiQ8I416_PLAF7
AccessioniPrimary (citable) accession number: Q8I416
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: December 20, 2017
This is version 111 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported