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Q8I402

- Q8I402_PLAF7

UniProt

Q8I402 - Q8I402_PLAF7

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Protein
Submitted name:

Cyclophilin, putative

Gene
PFE0505w
Organism
Plasmodium falciparum (isolate 3D7)
Status
Unreviewed - Annotation score: 1 out of 5 - Experimental evidence at protein leveli

Functioni

Catalytic activityi

Peptidylproline (omega=180) = peptidylproline (omega=0).SAAS annotations

GO - Molecular functioni

  1. cyclosporin A binding Source: GeneDB_Pfalciparum
  2. peptidyl-prolyl cis-trans isomerase activity Source: GeneDB_Pfalciparum

GO - Biological processi

  1. protein folding Source: UniProtKB-KW
  2. protein peptidyl-prolyl isomerization Source: GOC
Complete GO annotation...

Keywords - Molecular functioni

Isomerase, RotamaseUniRule annotationSAAS annotations

Names & Taxonomyi

Protein namesi
Submitted name:
Cyclophilin, putativeImported (EC:5.2.1.8Imported)
Gene namesi
ORF Names:PFE0505wImported
OrganismiPlasmodium falciparum (isolate 3D7)Imported
Taxonomic identifieri36329 [NCBI]
Taxonomic lineageiEukaryotaAlveolataApicomplexaAconoidasidaHaemosporidaPlasmodiumPlasmodium (Laverania)
ProteomesiUP000001450: Chromosome 5

Organism-specific databases

EuPathDBiPlasmoDB:PF3D7_0510200.

Interactioni

Protein-protein interaction databases

STRINGi5833.PFE0505w-1.

Structurei

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2FU0X-ray1.80A589-747[»]
ProteinModelPortaliQ8I402.
SMRiQ8I402. Positions 592-746.

Miscellaneous databases

EvolutionaryTraceiQ8I402.

Family & Domainsi

Sequence similaritiesi

Contains PPIase cyclophilin-type domain.SAAS annotations

Keywords - Domaini

RepeatUniRule annotation, WD repeatUniRule annotation

Phylogenomic databases

HOGENOMiHOG000213214.
KOiK12736.
OMAiDENYNDE.
PhylomeDBiQ8I402.

Family and domain databases

Gene3Di2.130.10.10. 1 hit.
2.40.100.10. 1 hit.
InterProiIPR029000. Cyclophilin-like_dom.
IPR020892. Cyclophilin-type_PPIase_CS.
IPR002130. Cyclophilin-type_PPIase_dom.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR017986. WD40_repeat_dom.
[Graphical view]
PfamiPF00160. Pro_isomerase. 1 hit.
PF00400. WD40. 1 hit.
[Graphical view]
PRINTSiPR00153. CSAPPISMRASE.
SMARTiSM00320. WD40. 3 hits.
[Graphical view]
SUPFAMiSSF50891. SSF50891. 1 hit.
SSF50978. SSF50978. 2 hits.
PROSITEiPS00170. CSA_PPIASE_1. 1 hit.
PS50072. CSA_PPIASE_2. 1 hit.
PS50082. WD_REPEATS_2. 1 hit.
PS50294. WD_REPEATS_REGION. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8I402-1 [UniParc]FASTAAdd to Basket

« Hide

MSKNDEYKNE KGEGEELPSS DGESSDGSFG PVPLQQNKDN INDENYNDEN    50
YNDENYNDKN YNDNDYISGN EKDVVLLDSK KKKKNSVSCS SSSSINIPEN 100
EELLNKKKRK VKGIIEENKK NQEKMKKKKI RINNDIYLKN LPTNKNYQVS 150
YMHTDIVTHV VVSNKKKYII TASLNGIIKF WYKNIGCIEF VKHFKIHSDE 200
IINIFISEDE EHLGSLSKDK TYKQFDITSF DMNIVIKLSF IPRTGEFIYS 250
SIFSTEVKVA ISSSEKACIY IYKPLESDIC IQTIDFGCCN IIEIIKYNKF 300
YDLCVFSDNE GLLDIVDVTN FKFPTSKEEK KSKTNNNMDH KLIDFMNKRY 350
PIKKINFSFK SETDLYELCK YKTYALCISL SLDGEYMAIL SENYFLRIYK 400
FESMKLYRVY DESTEMYLTA QNDPLKKELH IDSFDFGKRL FIEKEIKKYM 450
KNQNINFNMI SFDESNQYII YSTFIGIKVV NFITNQLCYI IGKNEANLRY 500
LSISIYQNII PINKVRTNIH ESLYINEKNI SDCALFCTVY KKARFYVFSK 550
KKLNEHELDD RDIYNEQPTK NDVNSLISNP LKNIETIHKN TPKSAIIYTT 600
MGDIHISLFY KECKKTVQNF SVHSINGYYN NCIFHRVIKH FMVQTGDPSG 650
DGTGGESIWG NEFEDEFFDH LNHSKPFMVS MANCGPNTNG SQFFITTVPC 700
PWLDFKHTVF GKVTQGSKIV LDIEKVRTDK RDKPLEDIKI LNIKINN 747
Length:747
Mass (Da):87,040
Last modified:March 1, 2003 - v1
Checksum:iAD8E42A379460B8A
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL844504 Genomic DNA. Translation: CAD51467.1.
RefSeqiXP_001351660.1. XM_001351624.1.

Genome annotation databases

EnsemblProtistsiPFE0505w:mRNA; PFE0505w:pep; PFE0505w.
GeneIDi812836.
KEGGipfa:PFE0505w.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL844504 Genomic DNA. Translation: CAD51467.1 .
RefSeqi XP_001351660.1. XM_001351624.1.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
2FU0 X-ray 1.80 A 589-747 [» ]
ProteinModelPortali Q8I402.
SMRi Q8I402. Positions 592-746.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 5833.PFE0505w-1.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblProtistsi PFE0505w:mRNA ; PFE0505w:pep ; PFE0505w .
GeneIDi 812836.
KEGGi pfa:PFE0505w.

Organism-specific databases

EuPathDBi PlasmoDB:PF3D7_0510200.

Phylogenomic databases

HOGENOMi HOG000213214.
KOi K12736.
OMAi DENYNDE.
PhylomeDBi Q8I402.

Miscellaneous databases

EvolutionaryTracei Q8I402.

Family and domain databases

Gene3Di 2.130.10.10. 1 hit.
2.40.100.10. 1 hit.
InterProi IPR029000. Cyclophilin-like_dom.
IPR020892. Cyclophilin-type_PPIase_CS.
IPR002130. Cyclophilin-type_PPIase_dom.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR017986. WD40_repeat_dom.
[Graphical view ]
Pfami PF00160. Pro_isomerase. 1 hit.
PF00400. WD40. 1 hit.
[Graphical view ]
PRINTSi PR00153. CSAPPISMRASE.
SMARTi SM00320. WD40. 3 hits.
[Graphical view ]
SUPFAMi SSF50891. SSF50891. 1 hit.
SSF50978. SSF50978. 2 hits.
PROSITEi PS00170. CSA_PPIASE_1. 1 hit.
PS50072. CSA_PPIASE_2. 1 hit.
PS50082. WD_REPEATS_2. 1 hit.
PS50294. WD_REPEATS_REGION. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Isolate 3D7.
  2. "Sequence of Plasmodium falciparum chromosomes 1, 3-9 and 13."
    Hall N., Pain A., Berriman M., Churcher C.M., Harris B., Harris D., Mungall K.L., Bowman S., Atkin R., Baker S., Barron A., Brooks K., Buckee C.O., Burrows C., Cherevach I., Chillingworth C., Chillingworth T., Christodoulou Z.
    , Clark L., Clark R., Corton C., Cronin A., Davies R.M., Davis P., Dear P., Dearden F., Doggett J., Feltwell T., Goble A., Goodhead I., Gwilliam R., Hamlin N., Hance Z., Harper D., Hauser H., Hornsby T., Holroyd S., Horrocks P., Humphray S., Jagels K., James K.D., Johnson D., Kerhornou A., Knights A., Konfortov B., Kyes S., Larke N., Lawson D., Lennard N., Line A., Maddison M., Mclean J., Mooney P., Moule S., Murphy L., Oliver K., Ormond D., Price C., Quail M.A., Rabbinowitsch E., Rajandream M.A., Rutter S., Rutherford K.M., Sanders M., Simmonds M., Seeger K., Sharp S., Smith R., Squares R., Squares S., Stevens K., Taylor K., Tivey A., Unwin L., Whitehead S., Woodward J.R., Sulston J.E., Craig A., Newbold C., Barrell B.G.
    Nature 419:527-531(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Isolate 3D7.
  3. Cited for: X-RAY CRYSTALLOGRAPHY (1.80 ANGSTROMS) OF 589-747.

Entry informationi

Entry nameiQ8I402_PLAF7
AccessioniPrimary (citable) accession number: Q8I402
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: July 9, 2014
This is version 104 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureImported, Complete proteome, Reference proteome

External Data

Dasty 3

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