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Q8I402

- Q8I402_PLAF7

UniProt

Q8I402 - Q8I402_PLAF7

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Protein
Submitted name:

Cyclophilin, putative

Gene

PFE0505w

Organism
Plasmodium falciparum (isolate 3D7)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli

Functioni

Catalytic activityi

Peptidylproline (omega=180) = peptidylproline (omega=0).SAAS annotation

GO - Molecular functioni

  1. cyclosporin A binding Source: GeneDB_Pfalciparum
  2. peptidyl-prolyl cis-trans isomerase activity Source: GeneDB_Pfalciparum

GO - Biological processi

  1. protein folding Source: GeneDB_Pfalciparum
Complete GO annotation...

Keywords - Molecular functioni

Isomerase, RotamaseUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Cyclophilin, putativeImported (EC:5.2.1.8Imported)
Gene namesi
ORF Names:PFE0505wImported
OrganismiPlasmodium falciparum (isolate 3D7)Imported
Taxonomic identifieri36329 [NCBI]
Taxonomic lineageiEukaryotaAlveolataApicomplexaAconoidasidaHaemosporidaPlasmodiumPlasmodium (Laverania)
ProteomesiUP000001450: Chromosome 5

Organism-specific databases

EuPathDBiPlasmoDB:PF3D7_0510200.

Interactioni

Protein-protein interaction databases

STRINGi5833.PFE0505w-1.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2FU0X-ray1.80A589-747[»]
ProteinModelPortaliQ8I402.
SMRiQ8I402. Positions 154-186, 592-746.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ8I402.

Family & Domainsi

Sequence similaritiesi

Contains 1 PPIase cyclophilin-type domain.UniRule annotation
Contains PPIase cyclophilin-type domain.SAAS annotation

Keywords - Domaini

RepeatUniRule annotation, WD repeatUniRule annotation

Phylogenomic databases

HOGENOMiHOG000213214.
InParanoidiQ8I402.
KOiK12736.
OMAiDENYNDE.
PhylomeDBiQ8I402.

Family and domain databases

Gene3Di2.130.10.10. 1 hit.
2.40.100.10. 1 hit.
InterProiIPR029000. Cyclophilin-like_dom.
IPR020892. Cyclophilin-type_PPIase_CS.
IPR002130. Cyclophilin-type_PPIase_dom.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR017986. WD40_repeat_dom.
[Graphical view]
PfamiPF00160. Pro_isomerase. 1 hit.
PF00400. WD40. 1 hit.
[Graphical view]
PRINTSiPR00153. CSAPPISMRASE.
SMARTiSM00320. WD40. 3 hits.
[Graphical view]
SUPFAMiSSF50891. SSF50891. 1 hit.
SSF50978. SSF50978. 2 hits.
PROSITEiPS00170. CSA_PPIASE_1. 1 hit.
PS50072. CSA_PPIASE_2. 1 hit.
PS50082. WD_REPEATS_2. 1 hit.
PS50294. WD_REPEATS_REGION. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8I402-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSKNDEYKNE KGEGEELPSS DGESSDGSFG PVPLQQNKDN INDENYNDEN
60 70 80 90 100
YNDENYNDKN YNDNDYISGN EKDVVLLDSK KKKKNSVSCS SSSSINIPEN
110 120 130 140 150
EELLNKKKRK VKGIIEENKK NQEKMKKKKI RINNDIYLKN LPTNKNYQVS
160 170 180 190 200
YMHTDIVTHV VVSNKKKYII TASLNGIIKF WYKNIGCIEF VKHFKIHSDE
210 220 230 240 250
IINIFISEDE EHLGSLSKDK TYKQFDITSF DMNIVIKLSF IPRTGEFIYS
260 270 280 290 300
SIFSTEVKVA ISSSEKACIY IYKPLESDIC IQTIDFGCCN IIEIIKYNKF
310 320 330 340 350
YDLCVFSDNE GLLDIVDVTN FKFPTSKEEK KSKTNNNMDH KLIDFMNKRY
360 370 380 390 400
PIKKINFSFK SETDLYELCK YKTYALCISL SLDGEYMAIL SENYFLRIYK
410 420 430 440 450
FESMKLYRVY DESTEMYLTA QNDPLKKELH IDSFDFGKRL FIEKEIKKYM
460 470 480 490 500
KNQNINFNMI SFDESNQYII YSTFIGIKVV NFITNQLCYI IGKNEANLRY
510 520 530 540 550
LSISIYQNII PINKVRTNIH ESLYINEKNI SDCALFCTVY KKARFYVFSK
560 570 580 590 600
KKLNEHELDD RDIYNEQPTK NDVNSLISNP LKNIETIHKN TPKSAIIYTT
610 620 630 640 650
MGDIHISLFY KECKKTVQNF SVHSINGYYN NCIFHRVIKH FMVQTGDPSG
660 670 680 690 700
DGTGGESIWG NEFEDEFFDH LNHSKPFMVS MANCGPNTNG SQFFITTVPC
710 720 730 740
PWLDFKHTVF GKVTQGSKIV LDIEKVRTDK RDKPLEDIKI LNIKINN
Length:747
Mass (Da):87,040
Last modified:March 1, 2003 - v1
Checksum:iAD8E42A379460B8A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL844504 Genomic DNA. Translation: CAD51467.1.
RefSeqiXP_001351660.1. XM_001351624.1.

Genome annotation databases

EnsemblProtistsiPFE0505w:mRNA; PFE0505w:pep; PFE0505w.
GeneIDi812836.
KEGGipfa:PFE0505w.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL844504 Genomic DNA. Translation: CAD51467.1 .
RefSeqi XP_001351660.1. XM_001351624.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
2FU0 X-ray 1.80 A 589-747 [» ]
ProteinModelPortali Q8I402.
SMRi Q8I402. Positions 154-186, 592-746.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 5833.PFE0505w-1.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblProtistsi PFE0505w:mRNA ; PFE0505w:pep ; PFE0505w .
GeneIDi 812836.
KEGGi pfa:PFE0505w.

Organism-specific databases

EuPathDBi PlasmoDB:PF3D7_0510200.

Phylogenomic databases

HOGENOMi HOG000213214.
InParanoidi Q8I402.
KOi K12736.
OMAi DENYNDE.
PhylomeDBi Q8I402.

Miscellaneous databases

EvolutionaryTracei Q8I402.

Family and domain databases

Gene3Di 2.130.10.10. 1 hit.
2.40.100.10. 1 hit.
InterProi IPR029000. Cyclophilin-like_dom.
IPR020892. Cyclophilin-type_PPIase_CS.
IPR002130. Cyclophilin-type_PPIase_dom.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR017986. WD40_repeat_dom.
[Graphical view ]
Pfami PF00160. Pro_isomerase. 1 hit.
PF00400. WD40. 1 hit.
[Graphical view ]
PRINTSi PR00153. CSAPPISMRASE.
SMARTi SM00320. WD40. 3 hits.
[Graphical view ]
SUPFAMi SSF50891. SSF50891. 1 hit.
SSF50978. SSF50978. 2 hits.
PROSITEi PS00170. CSA_PPIASE_1. 1 hit.
PS50072. CSA_PPIASE_2. 1 hit.
PS50082. WD_REPEATS_2. 1 hit.
PS50294. WD_REPEATS_REGION. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Isolate 3D7Imported.
  2. "Sequence of Plasmodium falciparum chromosomes 1, 3-9 and 13."
    Hall N., Pain A., Berriman M., Churcher C.M., Harris B., Harris D., Mungall K.L., Bowman S., Atkin R., Baker S., Barron A., Brooks K., Buckee C.O., Burrows C., Cherevach I., Chillingworth C., Chillingworth T., Christodoulou Z.
    , Clark L., Clark R., Corton C., Cronin A., Davies R.M., Davis P., Dear P., Dearden F., Doggett J., Feltwell T., Goble A., Goodhead I., Gwilliam R., Hamlin N., Hance Z., Harper D., Hauser H., Hornsby T., Holroyd S., Horrocks P., Humphray S., Jagels K., James K.D., Johnson D., Kerhornou A., Knights A., Konfortov B., Kyes S., Larke N., Lawson D., Lennard N., Line A., Maddison M., Mclean J., Mooney P., Moule S., Murphy L., Oliver K., Ormond D., Price C., Quail M.A., Rabbinowitsch E., Rajandream M.A., Rutter S., Rutherford K.M., Sanders M., Simmonds M., Seeger K., Sharp S., Smith R., Squares R., Squares S., Stevens K., Taylor K., Tivey A., Unwin L., Whitehead S., Woodward J.R., Sulston J.E., Craig A., Newbold C., Barrell B.G.
    Nature 419:527-531(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Isolate 3D7Imported.
  3. Cited for: X-RAY CRYSTALLOGRAPHY (1.80 ANGSTROMS) OF 589-747.

Entry informationi

Entry nameiQ8I402_PLAF7
AccessioniPrimary (citable) accession number: Q8I402
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: November 26, 2014
This is version 107 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureImported, Complete proteome, Reference proteomeImported

External Data

Dasty 3