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Q8I402 (Q8I402_PLAF7) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 104. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein names
EC=5.2.1.8 EMBL CAD51467.1
Gene names
ORF Names:PFE0505w EMBL CAD51467.1
OrganismPlasmodium falciparum (isolate 3D7) [Reference proteome] EMBL CAD51467.1
Taxonomic identifier36329 [NCBI]
Taxonomic lineageEukaryotaAlveolataApicomplexaAconoidasidaHaemosporidaPlasmodiumPlasmodium (Laverania)

Protein attributes

Sequence length747 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

Peptidylproline (omega=180) = peptidylproline (omega=0). SAAS SAAS002130

Sequence similarities

Contains 1 PPIase cyclophilin-type domain. RuleBase RU003420

Contains PPIase cyclophilin-type domain. SAAS SAAS020892

Sequences

Sequence LengthMass (Da)Tools
Q8I402 [UniParc].

Last modified March 1, 2003. Version 1.
Checksum: AD8E42A379460B8A

FASTA74787,040
        10         20         30         40         50         60 
MSKNDEYKNE KGEGEELPSS DGESSDGSFG PVPLQQNKDN INDENYNDEN YNDENYNDKN 

        70         80         90        100        110        120 
YNDNDYISGN EKDVVLLDSK KKKKNSVSCS SSSSINIPEN EELLNKKKRK VKGIIEENKK 

       130        140        150        160        170        180 
NQEKMKKKKI RINNDIYLKN LPTNKNYQVS YMHTDIVTHV VVSNKKKYII TASLNGIIKF 

       190        200        210        220        230        240 
WYKNIGCIEF VKHFKIHSDE IINIFISEDE EHLGSLSKDK TYKQFDITSF DMNIVIKLSF 

       250        260        270        280        290        300 
IPRTGEFIYS SIFSTEVKVA ISSSEKACIY IYKPLESDIC IQTIDFGCCN IIEIIKYNKF 

       310        320        330        340        350        360 
YDLCVFSDNE GLLDIVDVTN FKFPTSKEEK KSKTNNNMDH KLIDFMNKRY PIKKINFSFK 

       370        380        390        400        410        420 
SETDLYELCK YKTYALCISL SLDGEYMAIL SENYFLRIYK FESMKLYRVY DESTEMYLTA 

       430        440        450        460        470        480 
QNDPLKKELH IDSFDFGKRL FIEKEIKKYM KNQNINFNMI SFDESNQYII YSTFIGIKVV 

       490        500        510        520        530        540 
NFITNQLCYI IGKNEANLRY LSISIYQNII PINKVRTNIH ESLYINEKNI SDCALFCTVY 

       550        560        570        580        590        600 
KKARFYVFSK KKLNEHELDD RDIYNEQPTK NDVNSLISNP LKNIETIHKN TPKSAIIYTT 

       610        620        630        640        650        660 
MGDIHISLFY KECKKTVQNF SVHSINGYYN NCIFHRVIKH FMVQTGDPSG DGTGGESIWG 

       670        680        690        700        710        720 
NEFEDEFFDH LNHSKPFMVS MANCGPNTNG SQFFITTVPC PWLDFKHTVF GKVTQGSKIV 

       730        740 
LDIEKVRTDK RDKPLEDIKI LNIKINN 

« Hide

References

« Hide 'large scale' references
[1]"Genome sequence of the human malaria parasite Plasmodium falciparum."
Gardner M.J., Hall N., Fung E., White O., Berriman M., Hyman R.W., Carlton J.M., Pain A., Nelson K.E., Bowman S., Paulsen I.T., James K.D., Eisen J.A., Rutherford K.M., Salzberg S.L., Craig A., Kyes S., Chan M.-S. expand/collapse author list , Nene V., Shallom S.J., Suh B., Peterson J., Angiuoli S., Pertea M., Allen J., Selengut J., Haft D., Mather M.W., Vaidya A.B., Martin D.M.A., Fairlamb A.H., Fraunholz M.J., Roos D.S., Ralph S.A., McFadden G.I., Cummings L.M., Subramanian G.M., Mungall C., Venter J.C., Carucci D.J., Hoffman S.L., Newbold C., Davis R.W., Fraser C.M., Barrell B.G.
Nature 419:498-511(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Isolate 3D7.
[2]"Sequence of Plasmodium falciparum chromosomes 1, 3-9 and 13."
Hall N., Pain A., Berriman M., Churcher C.M., Harris B., Harris D., Mungall K.L., Bowman S., Atkin R., Baker S., Barron A., Brooks K., Buckee C.O., Burrows C., Cherevach I., Chillingworth C., Chillingworth T., Christodoulou Z. expand/collapse author list , Clark L., Clark R., Corton C., Cronin A., Davies R.M., Davis P., Dear P., Dearden F., Doggett J., Feltwell T., Goble A., Goodhead I., Gwilliam R., Hamlin N., Hance Z., Harper D., Hauser H., Hornsby T., Holroyd S., Horrocks P., Humphray S., Jagels K., James K.D., Johnson D., Kerhornou A., Knights A., Konfortov B., Kyes S., Larke N., Lawson D., Lennard N., Line A., Maddison M., Mclean J., Mooney P., Moule S., Murphy L., Oliver K., Ormond D., Price C., Quail M.A., Rabbinowitsch E., Rajandream M.A., Rutter S., Rutherford K.M., Sanders M., Simmonds M., Seeger K., Sharp S., Smith R., Squares R., Squares S., Stevens K., Taylor K., Tivey A., Unwin L., Whitehead S., Woodward J.R., Sulston J.E., Craig A., Newbold C., Barrell B.G.
Nature 419:527-531(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Isolate 3D7.
[3]"Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms."
Vedadi M., Lew J., Artz J., Amani M., Zhao Y., Dong A., Wasney G.A., Gao M., Hills T., Brokx S., Qiu W., Sharma S., Diassiti A., Alam Z., Melone M., Mulichak A., Wernimont A., Bray J. expand/collapse author list , Loppnau P., Plotnikova O., Newberry K., Sundararajan E., Houston S., Walker J., Tempel W., Bochkarev A., Kozieradzki I., Edwards A., Arrowsmith C., Roos D., Kain K., Hui R.
Mol. Biochem. Parasitol. 151:100-110(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (1.80 ANGSTROMS) OF 589-747.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL844504 Genomic DNA. Translation: CAD51467.1.
RefSeqXP_001351660.1. XM_001351624.1.

3D structure databases

PDBe
RCSB-PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
2FU0X-ray1.80A589-747[»]
ProteinModelPortalQ8I402.
SMRQ8I402. Positions 592-746.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING5833.PFE0505w-1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsPFE0505w:mRNA; PFE0505w:pep; PFE0505w.
GeneID812836.
KEGGpfa:PFE0505w.

Organism-specific databases

EuPathDBPlasmoDB:PF3D7_0510200.

Phylogenomic databases

HOGENOMHOG000213214.
KOK12736.
OMADENYNDE.
PhylomeDBQ8I402.

Family and domain databases

Gene3D2.130.10.10. 1 hit.
2.40.100.10. 1 hit.
InterProIPR029000. Cyclophilin-like_dom.
IPR020892. Cyclophilin-type_PPIase_CS.
IPR002130. Cyclophilin-type_PPIase_dom.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR017986. WD40_repeat_dom.
[Graphical view]
PfamPF00160. Pro_isomerase. 1 hit.
PF00400. WD40. 1 hit.
[Graphical view]
PRINTSPR00153. CSAPPISMRASE.
SMARTSM00320. WD40. 3 hits.
[Graphical view]
SUPFAMSSF50891. SSF50891. 1 hit.
SSF50978. SSF50978. 2 hits.
PROSITEPS00170. CSA_PPIASE_1. 1 hit.
PS50072. CSA_PPIASE_2. 1 hit.
PS50082. WD_REPEATS_2. 1 hit.
PS50294. WD_REPEATS_REGION. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

EvolutionaryTraceQ8I402.

Entry information

Entry nameQ8I402_PLAF7
AccessionPrimary (citable) accession number: Q8I402
Entry history
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: July 9, 2014
This is version 104 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)