Q8I3H4 (Q8I3H4_PLAF7) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Apicoplast TIC22, putative EMBL CAD51654.1

Gene names

ORF Names:

PFE1460w EMBL CAD51654.1

Organism

Plasmodium falciparum (isolate 3D7) [Reference proteome]

Taxonomic identifier

36329 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Alveolata › Apicomplexa › Aconoidasida › Haemosporida › Plasmodium › Plasmodium (Laverania) › Plasmodium falciparum

Protein attributes

Sequence length	279 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Technical term	3D-structure PDB 4E6Z Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	apicoplast Inferred from direct assay PubMed 11738814. Source: GeneDB_Pfalciparum
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8I3H4 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: 4FFB87C4417B0CAE	FASTA	279	33,474
	10 20 30 40 50 60 MCLLLFICLY FARGIYCLKT LNGLSRDINN SIYLRNNVHK KKRLVDCNLC MLKHKFRLSF 70 80 90 100 110 120 WKKRYDERPI EEKLEVIPVF LITNYNSSPY IFQENEKQVC YMFLCPYDAE NMLNDMIKYN 130 140 150 160 170 180 GMKYNGNIKI HNITMKKAYE LMKEFLQLEK MEVNKEDSKK KQNIYWKLIS SKRQLQNALY 190 200 210 220 230 240 YLSFTKKSEL MYPVFYAENL YIQKDGSNII PLFFDLEDLK EAIEEQKNKA LSKVDYKIKV 250 260 270 LNMVDLIFTE DHKKFGFVPS TQSVKYLDKL NIGTKKTYF

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Genome sequence of the human malaria parasite Plasmodium falciparum." Gardner M.J., Hall N., Fung E., White O., Berriman M., Hyman R.W., Carlton J.M., Pain A., Nelson K.E., Bowman S., Paulsen I.T., James K.D., Eisen J.A., Rutherford K.M., Salzberg S.L., Craig A., Kyes S., Chan M.-S. , Nene V., Shallom S.J., Suh B., Peterson J., Angiuoli S., Pertea M., Allen J., Selengut J., Haft D., Mather M.W., Vaidya A.B., Martin D.M.A., Fairlamb A.H., Fraunholz M.J., Roos D.S., Ralph S.A., McFadden G.I., Cummings L.M., Subramanian G.M., Mungall C., Venter J.C., Carucci D.J., Hoffman S.L., Newbold C., Davis R.W., Fraser C.M., Barrell B.G. Nature 419:498-511(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Isolate 3D7.
[2]	"Sequence of Plasmodium falciparum chromosomes 1, 3-9 and 13." Hall N., Pain A., Berriman M., Churcher C.M., Harris B., Harris D., Mungall K.L., Bowman S., Atkin R., Baker S., Barron A., Brooks K., Buckee C.O., Burrows C., Cherevach I., Chillingworth C., Chillingworth T., Christodoulou Z. , Clark L., Clark R., Corton C., Cronin A., Davies R.M., Davis P., Dear P., Dearden F., Doggett J., Feltwell T., Goble A., Goodhead I., Gwilliam R., Hamlin N., Hance Z., Harper D., Hauser H., Hornsby T., Holroyd S., Horrocks P., Humphray S., Jagels K., James K.D., Johnson D., Kerhornou A., Knights A., Konfortov B., Kyes S., Larke N., Lawson D., Lennard N., Line A., Maddison M., Mclean J., Mooney P., Moule S., Murphy L., Oliver K., Ormond D., Price C., Quail M.A., Rabbinowitsch E., Rajandream M.A., Rutter S., Rutherford K.M., Sanders M., Simmonds M., Seeger K., Sharp S., Smith R., Squares R., Squares S., Stevens K., Taylor K., Tivey A., Unwin L., Whitehead S., Woodward J.R., Sulston J.E., Craig A., Newbold C., Barrell B.G. Nature 419:527-531(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Isolate 3D7.
[3]	"Tic22 is an essential chaperone required for protein import into the apicoplast." Glaser S., van Dooren G.G., Agrawal S., Brooks C.F., McFadden G.I., Striepen B., Higgins M.K. J. Biol. Chem. 287:39505-39512(2012) [PubMed] [Europe PMC] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (2.15 ANGSTROMS).

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AL844504 Genomic DNA. Translation: CAD51654.1.

RefSeq

XP_001351847.1. XM_001351811.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
4E6Z	X-ray	2.15	A	1-279	[»]

ProteinModelPortal

Q8I3H4.

ModBase

Search...

Protein-protein interaction databases

STRING

5833.PFE1460w-1.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

EnsemblProtists

PFE1460w:mRNA; PFE1460w:pep; PFE1460w.

GeneID

813106.

KEGG

pfa:PFE1460w.

Organism-specific databases

EuPathDB

PlasmoDB:PF3D7_0529300.

Phylogenomic databases

HOGENOM

HOG000283623.

ProtClustDB

CLSZ2444874.

Family and domain databases

InterPro

IPR007378. Tic22-like.
[Graphical view]

Pfam

PF04278. Tic22. 1 hit.
[Graphical view]

ProtoNet

Search...

Entry information

Entry name

Q8I3H4_PLAF7

Accession

Primary (citable) accession number: Q8I3H4

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2003
Last sequence update:	March 1, 2003
Last modified:	April 3, 2013
This is version 47 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)