Reviewed, UniProtKB/Swiss-Prot Q8I1E5 (EIF3J_DROPS)

Names and origin

Protein names

Recommended name:
    Eukaryotic translation initiation factor 3 subunit J
      Short name=eIF3j

Gene names

Name:	Adam
ORF Names:	GA11426

Organism

Drosophila pseudoobscura pseudoobscura (Fruit fly) [Complete proteome]

Taxonomic identifier

46245 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	240 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome By similarity.
Subunit structure	Component of the eukaryotic translation initiation factor 3 (eIF-3) complex. The eIF-3 complex interacts with pix By similarity.
Subcellular location	Cytoplasm Probable.
Sequence similarities	Belongs to the eIF-3 subunit J family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Molecular function	Initiation factor
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	translation Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	translation initiation factor activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 240	240	Eukaryotic translation initiation factor 3 subunit J		PRO_0000365138

Sequences

	Sequence		Length	Mass (Da)
	Q8I1E5-1 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: 76D1A9CCBDDD20C4	FASTA	240	27,272
	10 20 30 40 50 60 MADDWESAAD SEIILQNAAS TVNKWEGEDD DDDVKESWED EEEKKDEENE KPTITDVPVK 70 80 90 100 110 120 TKPSKALKAK LEEQARLEEE KEAKRLASLT PEEKLAEKLR LQKIQEDSDL NHALDTFGVT 130 140 150 160 170 180 RAETNGNGLD SFNPETKEQF KEFGSALSWK VGQYRESAEF PQFVEDLVRG LCIHLSAADI 190 200 210 220 230 240 KKVKMSVEIL HSEKLKMEKA IAKKAAGKNK GKATLRTESD DIDDYKKYGN DFSEDYDDFM

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Assessing the impact of comparative genomic sequence data on the functional annotation of the Drosophila genome." Bergman C.M., Pfeiffer B.D., Rincon-Limas D.E., Hoskins R.A., Gnirke A., Mungall C.J., Wang A.M., Kronmiller B., Pacleb J.M., Park S., Stapleton M., Wan K.H., George R.A., de Jong P.J., Botas J., Rubin G.M., Celniker S.E. Genome Biol. 3:RESEARCH0086.1-RESEARCH0086.20(2002) [PubMed: 12537575] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]	"Comparative genome sequencing of Drosophila pseudoobscura: chromosomal, gene, and cis-element evolution." Richards S., Liu Y., Bettencourt B.R., Hradecky P., Letovsky S., Nielsen R., Thornton K., Hubisz M.J., Chen R., Meisel R.P., Couronne O., Hua S., Smith M.A., Zhang P., Liu J., Bussemaker H.J., van Batenburg M.F., Howells S.L. , Scherer S.E., Sodergren E., Matthews B.B., Crosby M.A., Schroeder A.J., Ortiz-Barrientos D., Rives C.M., Metzker M.L., Muzny D.M., Scott G., Steffen D., Wheeler D.A., Worley K.C., Havlak P., Durbin K.J., Egan A., Gill R., Hume J., Morgan M.B., Miner G., Hamilton C., Huang Y., Waldron L., Verduzco D., Clerc-Blankenburg K.P., Dubchak I., Noor M.A.F., Anderson W., White K.P., Clark A.G., Schaeffer S.W., Gelbart W.M., Weinstock G.M., Gibbs R.A. Genome Res. 15:1-18(2005) [PubMed: 15632085] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: MV2-25.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AY190942 Genomic DNA. Translation: AAO01025.1. CM000071 Genomic DNA. Translation: EAL25807.2.
RefSeq	XP_001361229.2.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	4804711.
KEGG	dpo:Dpse_GA11426.
Organism-specific databases
FlyBase	FBgn0064448. Dpse\Adam.
Phylogenomic databases
InParanoid	Q8I1E5.
OrthoDB	EOG9SJ5N4.
Family and domain databases
InterPro	IPR013906. eIF3_subunit. [Graphical view]
PANTHER	PTHR21681. eIF3_subunit. 1 hit.
Pfam	PF08597. eIF3_subunit. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

EIF3J_DROPS

Accession

Primary (citable) accession number: Q8I1E5
Secondary accession number(s): Q28Z08

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 3, 2009
Last sequence update:	March 1, 2003
Last modified:	December 15, 2009
This is version 30 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

Drosophila annotation project