Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Endoplasmin homolog, putative

Gene

PF3D7_1222300

Organism
Plasmodium falciparum (isolate 3D7)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • ATP binding Source: InterPro
  • unfolded protein binding Source: GeneDB

GO - Biological processi

  • protein folding Source: InterPro
  • response to heat Source: GeneDB

Enzyme and pathway databases

ReactomeiR-PFA-3371497. HSP90 chaperone cycle for steroid hormone receptors (SHR).
R-PFA-6798695. Neutrophil degranulation.
R-PFA-844456. The NLRP3 inflammasome.

Names & Taxonomyi

Protein namesi
Submitted name:
Endoplasmin homolog, putativeImported
Submitted name:
Endoplasmin, putativeImported
Gene namesi
ORF Names:PF3D7_1222300Imported, PFL1070cImported
OrganismiPlasmodium falciparum (isolate 3D7)Imported
Taxonomic identifieri36329 [NCBI]
Taxonomic lineageiEukaryotaAlveolataApicomplexaAconoidasidaHaemosporidaPlasmodiidaePlasmodiumPlasmodium (Laverania)
Proteomesi
  • UP000001450 Componenti: Chromosome 12

Organism-specific databases

EuPathDBiPlasmoDB:PF3D7_1222300.

Subcellular locationi

GO - Cellular componenti

  • endoplasmic reticulum Source: GeneDB

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 28Sequence analysisAdd BLAST28
ChainiPRO_501194948429 – 821Sequence analysisAdd BLAST793

PTM databases

SwissPalmiQ8I0V4.

Interactioni

GO - Molecular functioni

  • unfolded protein binding Source: GeneDB

Protein-protein interaction databases

IntActiQ8I0V4. 1 interactor.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3PEHX-ray2.75A/B68-330[»]
3PEJX-ray2.81A/B68-330[»]
SMRiQ8I0V4.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ8I0V4.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini95 – 234HATPase_cInterPro annotationAdd BLAST140

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili467 – 494Sequence analysisAdd BLAST28

Keywords - Domaini

Coiled coilSequence analysis, SignalSequence analysis

Phylogenomic databases

HOGENOMiHOG000031988.
InParanoidiQ8I0V4.
KOiK09487.
OMAiESDPWKD.

Family and domain databases

CDDicd00075. HATPase_c. 1 hit.
Gene3Di1.20.120.790. 1 hit.
3.30.565.10. 1 hit.
HAMAPiMF_00505. HSP90. 1 hit.
InterProiView protein in InterPro
IPR003594. HATPase_C.
IPR036890. HATPase_C_sf.
IPR019805. Heat_shock_protein_90_CS.
IPR037196. HSP90_C.
IPR001404. Hsp90_fam.
IPR020575. Hsp90_N.
IPR020568. Ribosomal_S5_D2-typ_fold.
PANTHERiPTHR11528. PTHR11528. 1 hit.
PfamiView protein in Pfam
PF02518. HATPase_c. 1 hit.
PF00183. HSP90. 1 hit.
PIRSFiPIRSF002583. Hsp90. 1 hit.
PRINTSiPR00775. HEATSHOCK90.
SMARTiView protein in SMART
SM00387. HATPase_c. 1 hit.
SUPFAMiSSF110942. SSF110942. 1 hit.
SSF54211. SSF54211. 2 hits.
SSF55874. SSF55874. 1 hit.
PROSITEiView protein in PROSITE
PS00298. HSP90. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8I0V4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLNNIYSFF FLFFVLCVIQ ENVRRVLCDS SVEGDKGPSD DVSDSSGEKK
60 70 80 90 100
EVKRDRDTLE EIEEGEKPTE SMESHQYQTE VTRLMDIIVN SLYTQKEVFL
110 120 130 140 150
RELISNAADA LEKIRFLSLS DESVLGEEKK LEIRISANKE KNILSITDTG
160 170 180 190 200
IGMTKVDLIN NLGTIAKSGT SNFLEAISKS GGDMSLIGQF GVGFYSAFLV
210 220 230 240 250
ADKVIVYTKN NDDEQYIWES TADAKFTIYK DPRGATLKRG TRISLHLKED
260 270 280 290 300
ATNLLNDKKL MDLISKYSQF IQFPIYLLHE NVYTEEVLAD IAKDMVNDPN
310 320 330 340 350
YDSVKVEETD DPNKKTRTVE KKVKKWTLMN EQRPIWLRSP KELKDEDYKQ
360 370 380 390 400
FFSVLSGYND QPLYHIHFFA EGEIEFKCLI YIPSKAPSMN DQLYSKQNSL
410 420 430 440 450
KLYVRRVLVA DEFVEFLPRY MSFVKGVVDS DDLPLNVSRE QLQQNKILKA
460 470 480 490 500
VSKRIVRKIL DTFHKLYKEG KKNKETLRSE LENETDEEKK KEITKKLSEP
510 520 530 540 550
STYKLIYKEY RKFLKSGCYE DDINRNKIAK LLLFKTMQYP KSISLDTYIE
560 570 580 590 600
HMKPDQKFIY YASGDSYEYL AKIPQLQIFK KKNIDVLFLT ESVDESCIQR
610 620 630 640 650
VQEYEGKKFK SIQKGEISFE LTEEEKKKEQ QMQKMYKALI DVISDTLKNQ
660 670 680 690 700
IFKVEISRRL VDAPCAVVST EWGLSGQMEK LMKMNVSNSD QIKAMSGQKI
710 720 730 740 750
LEINPNHPIM IDLLKRSVTN PKDLELTNSI KIMYQSAKLA SGFDLEDTAD
760 770 780 790 800
LAQIVYDHIN QKLGVDNNLK IDDLDPSIFE TKKIEDENDS SKFEEEINID
810 820
DEIQKKDNNV DNESNDKSDE L
Length:821
Mass (Da):95,018
Last modified:March 1, 2003 - v1
Checksum:i47E7B0095BBF014A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014188 Genomic DNA. Translation: AAN36300.1.
LN999947 Genomic DNA. Translation: CZT99382.1.
RefSeqiXP_001350620.1. XM_001350584.1.

Genome annotation databases

EnsemblProtistsiCZT99382; CZT99382; PF3D7_1222300.
GeneDBiPF3D7_1222300.1:pep.
GeneIDi811266.
KEGGipfa:PFL1070c.

Similar proteinsi

Entry informationi

Entry nameiQ8I0V4_PLAF7
AccessioniPrimary (citable) accession number: Q8I0V4
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: March 28, 2018
This is version 126 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported