Q8I0G4 (YO44_CAEEL) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Uncharacterized protein ZK757.4

Gene names

ORF Names:

ZK757.4

Organism

Caenorhabditis elegans [Reference proteome]

Taxonomic identifier

6239 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Protostomia › Ecdysozoa › Nematoda › Chromadorea › Rhabditida › Rhabditoidea › Rhabditidae › Peloderinae › Caenorhabditis

Protein attributes

Sequence length	403 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Subcellular location	Membrane; Multi-pass membrane protein Potential.
Sequence similarities	Contains 1 DHHC-type zinc finger.

Ontologies

Keywords
Cellular component	Membrane
Domain	Transmembrane Transmembrane helix Zinc-finger
Ligand	Metal-binding Zinc
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 403	403	Uncharacterized protein ZK757.4		PRO_0000065548
Regions
	Transmembrane	17 – 37	21	Helical; Potential
	Transmembrane	55 – 75	21	Helical; Potential
	Transmembrane	176 – 196	21	Helical; Potential
	Transmembrane	239 – 259	21	Helical; Potential
	Zinc finger	132 – 182	51	DHHC-type

Sequences

	Sequence		Length	Mass (Da)
	Q8I0G4 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: 7F7BA549B147DE42	FASTA	403	46,452
	10 20 30 40 50 60 MSCRDCTRKG GCVYTTFWLV RFLPVVLVSL ATGWGIYAYT YELCILSIDN WPQRIIYLFI 70 80 90 100 110 120 FYALLILFYT SYLRTVYTKA WKPPQKYCIE GASKATYESV KDDERQLQLF LSDIARERDL 130 140 150 160 170 180 TLLVRGFDHG IRFCDKCCCI KPDRSHHCSM CEQCVLKFDH HCPWVNNCVN FGNYKYFILF 190 200 210 220 230 240 LAYGFIFCIW IAATTLPSFI DFWRHEYDMN KKQYDSIDSV IQRNLKHLHT VLSNGRFPLV 250 260 270 280 290 300 FLLFLSCMFS LSLSFLFFYH LYLTAKNRTT VESFRAPMID GKYAKDAFNH GIRANYREIF 310 320 330 340 350 360 GSHPLYWFLP VPSSIGDGCK FVMNDMTAMS AAAGNQVFVE MGNVPNGQSH AHPPIAQHHI 370 380 390 400 NLYSEQSSSA SEKEIKSVDD EITERSQVST ATTASPSHDS VTA

References

[1]	"2.2 Mb of contiguous nucleotide sequence from chromosome III of C. elegans." Wilson R., Ainscough R., Anderson K., Baynes C., Berks M., Bonfield J., Burton J., Connell M., Copsey T., Cooper J., Coulson A., Craxton M., Dear S., Du Z., Durbin R., Favello A., Fraser A., Fulton L. , Gardner A., Green P., Hawkins T., Hillier L., Jier M., Johnston L., Jones M., Kershaw J., Kirsten J., Laisster N., Latreille P., Lightning J., Lloyd C., Mortimore B., O'Callaghan M., Parsons J., Percy C., Rifken L., Roopra A., Saunders D., Shownkeen R., Sims M., Smaldon N., Smith A., Smith M., Sonnhammer E., Staden R., Sulston J., Thierry-Mieg J., Thomas K., Vaudin M., Vaughan K., Waterston R., Watson A., Weinstock L., Wilkinson-Sproat J., Wohldman P. Nature 368:32-38(1994) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Bristol N2.
[2]	"Genome sequence of the nematode C. elegans: a platform for investigating biology." The C. elegans sequencing consortium Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Bristol N2.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	Z29121, Z22180 Genomic DNA. Translation: CAD54174.2.
RefSeq	NP_001023032.1. NM_001027861.5.
3D structure databases
ModBase	Search...
Proteomic databases
PaxDb	Q8I0G4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblMetazoa	ZK757.4a; ZK757.4a; ZK757.4.
GeneID	191420.
KEGG	cel:CELE_ZK757.4.
UCSC	ZK757.4a. c. elegans.
Organism-specific databases
CTD	191420.
WormBase	ZK757.4a; CE32089; WBGene00014075.
Phylogenomic databases
eggNOG	COG5273.
GeneTree	ENSGT00670000097758.
HOGENOM	HOG000234777.
Gene expression databases
ArrayExpress	Q8I0G4.
Family and domain databases
InterPro	IPR001594. Znf_DHHC_palmitoyltrfase. [Graphical view]
Pfam	PF01529. zf-DHHC. 1 hit. [Graphical view]
PROSITE	PS50216. ZF_DHHC. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	949096.

Entry information

Entry name

YO44_CAEEL

Accession

Primary (citable) accession number: Q8I0G4

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 30, 2003
Last sequence update:	March 1, 2003
Last modified:	April 3, 2013
This is version 60 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Caenorhabditis annotation project