Q8HZR3 (FUT4_BOVIN) Reviewed, UniProtKB/Swiss-Prot
Last modified
November 16, 2011.
Version 53.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Alpha-(1,3)-fucosyltransferase EC=2.4.1.- Alternative name(s): Fucosyltransferase 4 Fucosyltransferase IV Short name=Fuc-TIV Short name=FucT-IV Galactoside 3-L-fucosyltransferase | ||
| Gene names |
| ||
| Organism | Bos taurus (Bovine) | ||
| Taxonomic identifier | 9913 [NCBI] | ||
| Taxonomic lineage | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Laurasiatheria › Cetartiodactyla › Ruminantia › Pecora › Bovidae › Bovinae › Bos |
Protein attributes
| Sequence length | 398 AA. |
| Sequence status | Complete. |
| Protein existence | Evidence at transcript level |
General annotation (Comments)
| Function | May catalyze alpha-1,3 glycosidic linkages involved in the expression of Lewis X/SSEA-1 and VIM-2 antigens By similarity. |
| Pathway | |
| Subcellular location | Golgi apparatus › Golgi stack membrane; Single-pass type II membrane protein By similarity. Note: Membrane-bound form in trans cisternae of Golgi By similarity. |
| Sequence similarities | Belongs to the glycosyltransferase 10 family. |
Ontologies
| Keywords | |
|---|---|
| Cellular component | Golgi apparatus Membrane |
| Domain | Signal-anchor Transmembrane Transmembrane helix |
| Molecular function | Glycosyltransferase Transferase |
| PTM | Glycoprotein |
| Technical term | Complete proteome Reference proteome |
| Gene Ontology (GO) | |
| Biological process | protein glycosylation Inferred from electronic annotation. Source: InterPro |
| Cellular component | Golgi cisterna membrane Inferred from electronic annotation. Source: UniProtKB-SubCell integral to membraneInferred from electronic annotation. Source: UniProtKB-KW |
| Molecular function | fucosyltransferase activity Inferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 398 | 398 | Alpha-(1,3)-fucosyltransferase | PRO_0000221099 | |||||
Regions | |||||||||
| Topological domain | 1 – 15 | 15 | Cytoplasmic Potential | ||||||
| Transmembrane | 16 – 40 | 25 | Helical; Signal-anchor for type II membrane protein; Potential | ||||||
| Topological domain | 41 – 398 | 358 | Lumenal Potential | ||||||
Amino acid modifications | |||||||||
| Glycosylation | 84 | 1 | N-linked (GlcNAc...) Potential | ||||||
| Glycosylation | 183 | 1 | N-linked (GlcNAc...) Potential | ||||||
| Glycosylation | 311 | 1 | N-linked (GlcNAc...) Potential | ||||||
Sequences
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References
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | AF531092 mRNA. Translation: AAN63882.1. |
| IPI | IPI00697209. |
| RefSeq | NP_777161.1. NM_174736.2. |
| UniGene | Bt.12767. |
3D structure databases | |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | Q8HZR3. |
Protein family/group databases | |
| CAZy | GT10. Glycosyltransferase Family 10. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| GeneID | 282854. |
| KEGG | bta:282854. |
Organism-specific databases | |
| CTD | 2526. |
Phylogenomic databases | |
| GeneTree | ENSGT00550000074250. |
| HOVERGEN | HBG000274. |
| InParanoid | Q8HZR3. |
| OrthoDB | EOG4H72BB. |
Family and domain databases | |
| InterPro | IPR001503. Glyco_trans_10. [Graphical view] |
| KO | K07632. |
| PANTHER | PTHR11929. Glyco_trans_10. 1 hit. |
| Pfam | PF00852. Glyco_transf_10. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | FUT4_BOVIN | ||||||||
| Accession | Primary (citable) accession number: Q8HZR3 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Chordata Protein Annotation Program | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

Clusters with