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Protein

C-C motif chemokine

Gene
N/A
Organism
Macaca mulatta (Rhesus macaque)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

CytokineUniRule annotationSAAS annotation

Keywords - Biological processi

ChemotaxisUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
C-C motif chemokineUniRule annotation
OrganismiMacaca mulatta (Rhesus macaque)Imported
Taxonomic identifieri9544 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeCercopithecinaeMacaca

Subcellular locationi

  • Secreted UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

SecretedUniRule annotation

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2626UniRule annotationAdd
BLAST
Chaini27 – 9670C-C motif chemokineUniRule annotationPRO_5005144479Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi9544.ENSMMUP00000017423.

Structurei

3D structure databases

ProteinModelPortaliQ8HYP6.
SMRiQ8HYP6. Positions 27-96.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini29 – 8961SCYInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the intercrine beta (chemokine CC) family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalUniRule annotation

Phylogenomic databases

eggNOGiENOG410J2BK. Eukaryota.
ENOG410ZGME. LUCA.
HOGENOMiHOG000036685.
HOVERGENiHBG017871.
KOiK14625.

Family and domain databases

InterProiIPR000827. Chemokine_CC_CS.
IPR001811. Chemokine_IL8-like_dom.
[Graphical view]
PfamiPF00048. IL8. 1 hit.
[Graphical view]
SMARTiSM00199. SCY. 1 hit.
[Graphical view]
SUPFAMiSSF54117. SSF54117. 1 hit.
PROSITEiPS00472. SMALL_CYTOKINES_CC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8HYP6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MCCTKSLLLA ALMSVLLLYL CSESEAASNF DCCLRYTDRI LHPKFIVGFT
60 70 80 90
QQLANETCDI NAVVFHTKKG LSVCANPKQT WVKLIVRRLS KKINKM
Length:96
Mass (Da):10,841
Last modified:March 1, 2003 - v1
Checksum:i578974EE79BFC32B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF449274 mRNA. Translation: AAN76078.1.
RefSeqiNP_001028026.1. NM_001032854.1.
UniGeneiMmu.3708.

Genome annotation databases

GeneIDi574182.
KEGGimcc:574182.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF449274 mRNA. Translation: AAN76078.1.
RefSeqiNP_001028026.1. NM_001032854.1.
UniGeneiMmu.3708.

3D structure databases

ProteinModelPortaliQ8HYP6.
SMRiQ8HYP6. Positions 27-96.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9544.ENSMMUP00000017423.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi574182.
KEGGimcc:574182.

Organism-specific databases

CTDi6364.

Phylogenomic databases

eggNOGiENOG410J2BK. Eukaryota.
ENOG410ZGME. LUCA.
HOGENOMiHOG000036685.
HOVERGENiHBG017871.
KOiK14625.

Family and domain databases

InterProiIPR000827. Chemokine_CC_CS.
IPR001811. Chemokine_IL8-like_dom.
[Graphical view]
PfamiPF00048. IL8. 1 hit.
[Graphical view]
SMARTiSM00199. SCY. 1 hit.
[Graphical view]
SUPFAMiSSF54117. SSF54117. 1 hit.
PROSITEiPS00472. SMALL_CYTOKINES_CC. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ8HYP6_MACMU
AccessioniPrimary (citable) accession number: Q8HYP6
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: June 8, 2016
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.