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Protein

60S ribosomal protein L19

Gene

RPL19

Organism
Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Names & Taxonomyi

Protein namesi
Recommended name:
60S ribosomal protein L19
Gene namesi
Name:RPL19
ORF Names:QbsB-11252, QccE-18201
OrganismiMacaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
Taxonomic identifieri9541 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeCercopithecinaeMacaca

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001311701 – 19660S ribosomal protein L19Add BLAST196

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei5CitrullineBy similarity1
Modified residuei13PhosphoserineBy similarity1
Modified residuei16CitrullineBy similarity1
Modified residuei38CitrullineBy similarity1
Modified residuei164PhosphoserineBy similarity1
Cross-linki181Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1)By similarity
Modified residuei187PhosphothreonineBy similarity1

Post-translational modificationi

Citrullinated by PADI4.By similarity

Keywords - PTMi

Citrullination, Isopeptide bond, Phosphoprotein, Ubl conjugation

Structurei

3D structure databases

ProteinModelPortaliQ8HXN9.
SMRiQ8HXN9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein L19e family.Curated

Phylogenomic databases

HOVERGENiHBG056059.

Family and domain databases

CDDicd01417. Ribosomal_L19e_E. 1 hit.
Gene3Di1.10.1200.60. 1 hit.
1.10.1650.10. 1 hit.
HAMAPiMF_01475. Ribosomal_L19e. 1 hit.
InterProiIPR000196. Ribosomal_L19/L19e.
IPR023638. Ribosomal_L19/L19e_CS.
IPR015972. Ribosomal_L19/L19e_dom1.
IPR015974. Ribosomal_L19/L19e_dom3.
IPR033935. Ribosomal_L19_euka.
[Graphical view]
PfamiPF01280. Ribosomal_L19e. 1 hit.
[Graphical view]
SMARTiSM01416. Ribosomal_L19e. 1 hit.
[Graphical view]
SUPFAMiSSF48140. SSF48140. 1 hit.
PROSITEiPS00526. RIBOSOMAL_L19E. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8HXN9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSMLRLQKRL ASSVLRCGKK KVWLDPNETN EIANANSRQQ IRKLIKDGLI
60 70 80 90 100
IRKPVTVHSR ARCRKNTLAR RKGRHMGIGK RKGTANARMP EKVTWMRRMR
110 120 130 140 150
ILRRLLRRYR ESKKIDRHMY HSLYLKVKGN VFKNKRILME HIHKLKADKA
160 170 180 190
RKKLLADQAE ARRSKTKEAR KRREERLQAK KEEIIKTLSK EEETKK
Length:196
Mass (Da):23,466
Last modified:August 16, 2004 - v2
Checksum:i4AF506393E526216
GO

Sequence cautioni

The sequence BAC21651 differs from that shown. Reason: Frameshift at positions 188, 191 and 194.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB093677 mRNA. Translation: BAC21651.1. Frameshift.
AB169688 mRNA. Translation: BAE01769.1.
RefSeqiXP_005584063.1. XM_005584006.2.
UniGeneiMfa.2091.

Genome annotation databases

GeneIDi101926814.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB093677 mRNA. Translation: BAC21651.1. Frameshift.
AB169688 mRNA. Translation: BAE01769.1.
RefSeqiXP_005584063.1. XM_005584006.2.
UniGeneiMfa.2091.

3D structure databases

ProteinModelPortaliQ8HXN9.
SMRiQ8HXN9.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi101926814.

Organism-specific databases

CTDi6143.

Phylogenomic databases

HOVERGENiHBG056059.

Family and domain databases

CDDicd01417. Ribosomal_L19e_E. 1 hit.
Gene3Di1.10.1200.60. 1 hit.
1.10.1650.10. 1 hit.
HAMAPiMF_01475. Ribosomal_L19e. 1 hit.
InterProiIPR000196. Ribosomal_L19/L19e.
IPR023638. Ribosomal_L19/L19e_CS.
IPR015972. Ribosomal_L19/L19e_dom1.
IPR015974. Ribosomal_L19/L19e_dom3.
IPR033935. Ribosomal_L19_euka.
[Graphical view]
PfamiPF01280. Ribosomal_L19e. 1 hit.
[Graphical view]
SMARTiSM01416. Ribosomal_L19e. 1 hit.
[Graphical view]
SUPFAMiSSF48140. SSF48140. 1 hit.
PROSITEiPS00526. RIBOSOMAL_L19E. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRL19_MACFA
AccessioniPrimary (citable) accession number: Q8HXN9
Secondary accession number(s): Q4R556
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 21, 2003
Last sequence update: August 16, 2004
Last modified: November 30, 2016
This is version 64 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Documents

  1. Ribosomal proteins
    Ribosomal proteins families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.