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Protein

NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial

Gene

NDUFB11

Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.By similarity

GO - Biological processi

Keywordsi

Biological processElectron transport, Respiratory chain, Transport

Enzyme and pathway databases

ReactomeiR-BTA-611105. Respiratory electron transport.
R-BTA-6799198. Complex I biogenesis.

Protein family/group databases

TCDBi3.D.1.6.1. the h(+) or na(+)-translocating nadh dehydrogenase (ndh) family.

Names & Taxonomyi

Protein namesi
Recommended name:
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial
Alternative name(s):
Complex I-ESSS
Short name:
CI-ESSS
NADH-ubiquinone oxidoreductase ESSS subunit
Gene namesi
Name:NDUFB11
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome X

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei89 – 109HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transit peptidei1 – 29Mitochondrion1 PublicationAdd BLAST29
ChainiPRO_000002005630 – 154NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrialAdd BLAST125

Proteomic databases

PaxDbiQ8HXG5.
PRIDEiQ8HXG5.

Expressioni

Gene expression databases

BgeeiENSBTAG00000047278.

Interactioni

Subunit structurei

Complex I is composed of 45 different subunits.1 Publication

Protein-protein interaction databases

CORUMiQ8HXG5.
DIPiDIP-38813N.
IntActiQ8HXG5. 2 interactors.
STRINGi9913.ENSBTAP00000055738.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
5LC5electron microscopy4.35g1-154[»]
5LDWelectron microscopy4.27g30-154[»]
5LDXelectron microscopy5.60g30-154[»]
SMRiQ8HXG5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the complex I NDUFB11 subunit family.Curated

Keywords - Domaini

Transit peptide, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG4808. Eukaryota.
ENOG41120A5. LUCA.
GeneTreeiENSGT00390000003022.
HOVERGENiHBG004073.
InParanoidiQ8HXG5.
KOiK11351.
OMAiYLPDYRM.
OrthoDBiEOG091G0WTH.
TreeFamiTF314671.

Family and domain databases

InterProiView protein in InterPro
IPR019329. NADH_UbQ_OxRdtase_ESSS_su.
PfamiView protein in Pfam
PF10183. ESSS. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q8HXG5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAARMLGLCG RRLLAVAATR GLPAARVRWE SSSSRAVIAP STLAGKRPSE
60 70 80 90 100
PTLRWQEDPE PEDENLYEKN PDSHGYDKDP AVDIWNMRVV FFFGFSIVLV
110 120 130 140 150
LGSTFVAYLP DYRMQEWARR EAERLVKYRE AHGLPIMESN CFDPSKIQLP

EDED
Length:154
Mass (Da):17,573
Last modified:May 16, 2006 - v2
Checksum:i5D0B30342901D748
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC102141 mRNA. Translation: AAI02142.1.
AJ510149 mRNA. Translation: CAD52868.1.
RefSeqiNP_001028792.1. NM_001033620.2.
UniGeneiBt.6494.

Genome annotation databases

EnsembliENSBTAT00000063308; ENSBTAP00000055738; ENSBTAG00000047278.
GeneIDi404161.
KEGGibta:404161.

Similar proteinsi

Entry informationi

Entry nameiNDUBB_BOVIN
AccessioniPrimary (citable) accession number: Q8HXG5
Secondary accession number(s): Q3T137
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 27, 2003
Last sequence update: May 16, 2006
Last modified: September 27, 2017
This is version 86 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families