SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q8HWN3

- Q8HWN3_HUMAN

UniProt

Q8HWN3 - Q8HWN3_HUMAN

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Submitted name:

MHC class II antigen

Gene
HLA-DRB1
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5 - Protein predictedi

Functioni

GO - Biological processi

  1. antigen processing and presentation of peptide or polysaccharide antigen via MHC class II Source: UniProtKB-KW
  2. immune response Source: InterPro
Complete GO annotation...

Keywords - Biological processi

Immunity

Names & Taxonomyi

Protein namesi
Submitted name:
MHC class II antigenImported
Gene namesi
Name:HLA-DRB1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. MHC class II protein complex Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane, MHC IIUniRule annotation

PTM / Processingi

Proteomic databases

PRIDEiQ8HWN3.

Expressioni

Gene expression databases

ArrayExpressiQ8HWN3.
BgeeiQ8HWN3.

Structurei

3D structure databases

ProteinModelPortaliQ8HWN3.

Family & Domainsi

Keywords - Domaini

TransmembraneUniRule annotation

Family and domain databases

Gene3Di3.10.320.10. 1 hit.
InterProiIPR011162. MHC_I/II-like_Ag-recog.
IPR014745. MHC_II_a/b_N.
IPR000353. MHC_II_b_N.
[Graphical view]
PfamiPF00969. MHC_II_beta. 1 hit.
[Graphical view]
ProDomiPD000328. MHC_II_b_N. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SMARTiSM00921. MHC_II_beta. 1 hit.
[Graphical view]
SUPFAMiSSF54452. SSF54452. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q8HWN3-1 [UniParc]FASTAAdd to Basket

« Hide

CHFFNGTERV RFLDRYFYNQ EESVRFDSDV GEFRAVTELG RPDAEYWNSQ   50
KDILEQARAA VDTYCRHNYG VVESFT 76
Length:76
Mass (Da):9,053
Last modified:March 1, 2003 - v1
Checksum:iF62FE07568A68C1A
GO

Non-terminal residue

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei76 – 761Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ507782 Genomic DNA. Translation: CAD47818.1.
UniGeneiHs.534322.
Hs.696211.
Hs.736560.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ507782 Genomic DNA. Translation: CAD47818.1 .
UniGenei Hs.534322.
Hs.696211.
Hs.736560.

3D structure databases

ProteinModelPortali Q8HWN3.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi Q8HWN3.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Miscellaneous databases

ChiTaRSi HLA-DRB1. human.

Gene expression databases

ArrayExpressi Q8HWN3.
Bgeei Q8HWN3.

Family and domain databases

Gene3Di 3.10.320.10. 1 hit.
InterProi IPR011162. MHC_I/II-like_Ag-recog.
IPR014745. MHC_II_a/b_N.
IPR000353. MHC_II_b_N.
[Graphical view ]
Pfami PF00969. MHC_II_beta. 1 hit.
[Graphical view ]
ProDomi PD000328. MHC_II_b_N. 1 hit.
[Graphical view ] [Entries sharing at least one domain ]
SMARTi SM00921. MHC_II_beta. 1 hit.
[Graphical view ]
SUPFAMi SSF54452. SSF54452. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "A novel HLA-DRB1*15 allele."
    Fae I., Fischer G.F.
    Submitted (SEP-2002) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: SJ187/37Imported.
    Tissue: BloodImported.

Entry informationi

Entry nameiQ8HWN3_HUMAN
AccessioniPrimary (citable) accession number: Q8HWN3
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: July 9, 2014
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi