Reviewed, UniProtKB/Swiss-Prot Q8H9D2 (NQR_SOLTU)

Names and origin

Protein names	Recommended name:     NAD(P)H:quinone oxidoreductase       Short name=NAD(P)H:QR     EC=1.6.5.2
Organism	Solanum tuberosum (Potato)
Taxonomic identifier	4113 [NCBI]
Taxonomic lineage	Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › asterids › lamiids › Solanales › Solanaceae › Solanoideae › Solaneae › Solanum

Protein attributes

Sequence length	194 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Function	The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinones involved in detoxification pathways By similarity.
Catalytic activity	NAD(P)H + a quinone = NAD(P)+ + a hydroquinone.
Cofactor	FMN By similarity.
Subunit structure	Homotetramer By similarity.
Induction	By P.infestans. Ref.1
Sequence similarities	Belongs to the ssuE family.

Ontologies

Keywords
Ligand	FMN Flavoprotein NAD NADP
Molecular function	Oxidoreductase
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	NAD(P)H dehydrogenase (quinone) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 194	194	NAD(P)H:quinone oxidoreductase		PRO_0000160602

Sequences

	Sequence		Length	Mass (Da)
	Q8H9D2-1 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: F5E003D1AEEAB40E	FASTA	194	21,316
	10 20 30 40 50 60 MAAQPVIKVA GLCGSLRKGS YNRGLLNAAM EICKDSITGM EIEYVDISPL PFLNTDLEVN 70 80 90 100 110 120 GTYPPVVEAF RKKIEEADCF LFASPEYNYS ITGPLKNAID WASRPPNVWA DKAAAMVSAG 130 140 150 160 170 180 GGFGGGRSQY HLRQIGVFLD LHFINKPEFF LNAFQQPPKF DSDGVLTDEE TKQRLRAVLL 190 ALQALALKLK GKCE

References

[1]	"Elicitation of primary and secondary metabolism during defense in the potato." Nakane E., Kawakita K., Doke N., Yoshioka H. J. Gen. Plant Pathol. 69:378-384(2003) Cited for: NUCLEOTIDE SEQUENCE [MRNA], INDUCTION.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AB061251 mRNA. Translation: BAC23037.1.
3D structure databases
ModBase	Search...
Enzyme and pathway databases
BRENDA	1.6.5.2. 296.
Family and domain databases
InterPro	IPR005025. FMN_red. [Graphical view]
Pfam	PF03358. FMN_red. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

NQR_SOLTU

Accession

Primary (citable) accession number: Q8H9D2

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 24, 2006
Last sequence update:	March 1, 2003
Last modified:	January 20, 2009
This is version 20 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

PPAP (Plant Proteome Annotation Project)