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Q8H7L6

- APY1_ORYSJ

UniProt

Q8H7L6 - APY1_ORYSJ

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Protein

Probable apyrase 1

Gene
APY1, Os03g0328400, LOC_Os03g21120, OSJNBb0014I10.10
Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the hydrolysis of phosphoanhydride bonds of nucleoside tri- and di-phosphates By similarity.

Catalytic activityi

A nucleoside 5'-triphosphate + 2 H2O = a nucleoside 5'-phosphate + 2 phosphate.

Cofactori

Calcium By similarity.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei211 – 2111Proton acceptor By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi89 – 9911ATP-binding InferredAdd
BLAST
Nucleotide bindingi235 – 24511ATP-binding InferredAdd
BLAST

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. hydrolase activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Ligandi

ATP-binding, Calcium, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable apyrase 1 (EC:3.6.1.5)
Short name:
OsAPY1
Alternative name(s):
ATP-diphosphatase
ATP-diphosphohydrolase
Adenosine diphosphatase
Short name:
ADPase
Gene namesi
Name:APY1
Ordered Locus Names:Os03g0328400, LOC_Os03g21120
ORF Names:OSJNBb0014I10.10
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza
ProteomesiUP000000763: Chromosome 3

Organism-specific databases

GrameneiQ8H7L6.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 2828Cytoplasmic Reviewed predictionAdd
BLAST
Transmembranei29 – 4921Helical; Signal-anchor for type II membrane protein; Reviewed predictionAdd
BLAST
Topological domaini50 – 489440Extracellular Reviewed predictionAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 489489Probable apyrase 1PRO_0000419907Add
BLAST

Family & Domainsi

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi12 – 165Poly-Gln
Compositional biasi368 – 3736Poly-Gly

Sequence similaritiesi

Belongs to the GDA1/CD39 NTPase family.

Keywords - Domaini

Signal-anchor, Transmembrane, Transmembrane helix

Phylogenomic databases

OMAiSYSKCRA.

Family and domain databases

InterProiIPR000407. GDA1_CD39_NTPase.
[Graphical view]
PANTHERiPTHR11782. PTHR11782. 1 hit.
PfamiPF01150. GDA1_CD39. 1 hit.
[Graphical view]
PROSITEiPS01238. GDA1_CD39_NTPASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8H7L6-1 [UniParc]FASTAAdd to Basket

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MRRFSAAAGA RQQQQQGEAV SDRVLRFRGV LVVVLAPVLL ISLVLLLMPR    50
APASATVEGS AGELVAAAGR RWGPRAVSGL GDGSTRYAVI FDAGSSGSRV 100
HVYCFDGNLD LLPIGKEIEL FKQKKPGLSA YAMDPQEAAK SLVSLLEEAE 150
KVIPVELREQ TPVRVGATAG LRALGTEKSE EILQAVRDLL QDKSSFRSQP 200
EWVTVLDGSQ EGAFQWVTIN YLLGNLGKPY SHTVGVVDLG GGSVQMAYAI 250
SEKDAGKAPP VAEGEDSYVK ELLLKGTTYY LYVHSYLRYG LLAARAEILK 300
AGEGNDYRNC MLEGHHGQYR YGDDIFEASG LSSGASYSKC RAVAVRALKV 350
DEPACTHMKC TFGGVWNGGG GDGQKNLFVA SFFFDRAAEA GFVNPKAPFA 400
KVKPSDFEEA ARRVCKLNVK DAQATYPDVS EENVPYLCMD LVYQYTLLVD 450
GFGVDPYQDI TLVKKVPYSN SFVEAAWPLG SAIEVASSS 489
Length:489
Mass (Da):52,799
Last modified:March 1, 2003 - v1
Checksum:i0BF6BF154488D38E
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC126222 Genomic DNA. Translation: AAN65004.1.
DP000009 Genomic DNA. Translation: ABF95735.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC126222 Genomic DNA. Translation: AAN65004.1 .
DP000009 Genomic DNA. Translation: ABF95735.1 .

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

Gramenei Q8H7L6.

Phylogenomic databases

OMAi SYSKCRA.

Family and domain databases

InterProi IPR000407. GDA1_CD39_NTPase.
[Graphical view ]
PANTHERi PTHR11782. PTHR11782. 1 hit.
Pfami PF01150. GDA1_CD39. 1 hit.
[Graphical view ]
PROSITEi PS01238. GDA1_CD39_NTPASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Sequence, annotation, and analysis of synteny between rice chromosome 3 and diverged grass species."
    The rice chromosome 3 sequencing consortium
    Buell C.R., Yuan Q., Ouyang S., Liu J., Zhu W., Wang A., Maiti R., Haas B., Wortman J., Pertea M., Jones K.M., Kim M., Overton L., Tsitrin T., Fadrosh D., Bera J., Weaver B., Jin S.
    , Johri S., Reardon M., Webb K., Hill J., Moffat K., Tallon L., Van Aken S., Lewis M., Utterback T., Feldblyum T., Zismann V., Iobst S., Hsiao J., de Vazeille A.R., Salzberg S.L., White O., Fraser C.M., Yu Y., Kim H., Rambo T., Currie J., Collura K., Kernodle-Thompson S., Wei F., Kudrna K., Ammiraju J.S.S., Luo M., Goicoechea J.L., Wing R.A., Henry D., Oates R., Palmer M., Pries G., Saski C., Simmons J., Soderlund C., Nelson W., de la Bastide M., Spiegel L., Nascimento L., Huang E., Preston R., Zutavern T., Palmer L., O'Shaughnessy A., Dike S., McCombie W.R., Minx P., Cordum H., Wilson R., Jin W., Lee H.R., Jiang J., Jackson S.
    Genome Res. 15:1284-1291(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Nipponbare.

Entry informationi

Entry nameiAPY1_ORYSJ
AccessioniPrimary (citable) accession number: Q8H7L6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 31, 2012
Last sequence update: March 1, 2003
Last modified: May 14, 2014
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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