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Q8H7L6

- APY1_ORYSJ

UniProt

Q8H7L6 - APY1_ORYSJ

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Protein

Probable apyrase 1

Gene

APY1

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the hydrolysis of phosphoanhydride bonds of nucleoside tri- and di-phosphates.By similarity

Catalytic activityi

A nucleoside 5'-triphosphate + 2 H2O = a nucleoside 5'-phosphate + 2 phosphate.

Cofactori

Calcium.By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei211 – 2111Proton acceptorBy similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi89 – 9911ATP-bindingCuratedAdd
BLAST
Nucleotide bindingi235 – 24511ATP-bindingCuratedAdd
BLAST

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. hydrolase activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Ligandi

ATP-binding, Calcium, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable apyrase 1 (EC:3.6.1.5)
Short name:
OsAPY1
Alternative name(s):
ATP-diphosphatase
ATP-diphosphohydrolase
Adenosine diphosphatase
Short name:
ADPase
Gene namesi
Name:APY1
Ordered Locus Names:Os03g0328400, LOC_Os03g21120
ORF Names:OSJNBb0014I10.10
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza
ProteomesiUP000000763: Chromosome 3

Organism-specific databases

GrameneiQ8H7L6.

Subcellular locationi

Membrane By similarity; Single-pass type II membrane protein By similarity

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 489489Probable apyrase 1PRO_0000419907Add
BLAST

Structurei

Topological domain

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 2828CytoplasmicSequence AnalysisAdd
BLAST
Topological domaini50 – 489440ExtracellularSequence AnalysisAdd
BLAST

Transmembrane

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei29 – 4921Helical; Signal-anchor for type II membrane proteinSequence AnalysisAdd
BLAST

Family & Domainsi

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi12 – 165Poly-Gln
Compositional biasi368 – 3736Poly-Gly

Sequence similaritiesi

Belongs to the GDA1/CD39 NTPase family.Curated

Keywords - Domaini

Signal-anchor, Transmembrane, Transmembrane helix

Phylogenomic databases

InParanoidiQ8H7L6.
OMAiSYSKCRA.

Family and domain databases

InterProiIPR000407. GDA1_CD39_NTPase.
[Graphical view]
PANTHERiPTHR11782. PTHR11782. 1 hit.
PfamiPF01150. GDA1_CD39. 1 hit.
[Graphical view]
PROSITEiPS01238. GDA1_CD39_NTPASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8H7L6-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MRRFSAAAGA RQQQQQGEAV SDRVLRFRGV LVVVLAPVLL ISLVLLLMPR
60 70 80 90 100
APASATVEGS AGELVAAAGR RWGPRAVSGL GDGSTRYAVI FDAGSSGSRV
110 120 130 140 150
HVYCFDGNLD LLPIGKEIEL FKQKKPGLSA YAMDPQEAAK SLVSLLEEAE
160 170 180 190 200
KVIPVELREQ TPVRVGATAG LRALGTEKSE EILQAVRDLL QDKSSFRSQP
210 220 230 240 250
EWVTVLDGSQ EGAFQWVTIN YLLGNLGKPY SHTVGVVDLG GGSVQMAYAI
260 270 280 290 300
SEKDAGKAPP VAEGEDSYVK ELLLKGTTYY LYVHSYLRYG LLAARAEILK
310 320 330 340 350
AGEGNDYRNC MLEGHHGQYR YGDDIFEASG LSSGASYSKC RAVAVRALKV
360 370 380 390 400
DEPACTHMKC TFGGVWNGGG GDGQKNLFVA SFFFDRAAEA GFVNPKAPFA
410 420 430 440 450
KVKPSDFEEA ARRVCKLNVK DAQATYPDVS EENVPYLCMD LVYQYTLLVD
460 470 480
GFGVDPYQDI TLVKKVPYSN SFVEAAWPLG SAIEVASSS
Length:489
Mass (Da):52,799
Last modified:March 1, 2003 - v1
Checksum:i0BF6BF154488D38E
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC126222 Genomic DNA. Translation: AAN65004.1.
DP000009 Genomic DNA. Translation: ABF95735.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC126222 Genomic DNA. Translation: AAN65004.1 .
DP000009 Genomic DNA. Translation: ABF95735.1 .

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

Gramenei Q8H7L6.

Phylogenomic databases

InParanoidi Q8H7L6.
OMAi SYSKCRA.

Family and domain databases

InterProi IPR000407. GDA1_CD39_NTPase.
[Graphical view ]
PANTHERi PTHR11782. PTHR11782. 1 hit.
Pfami PF01150. GDA1_CD39. 1 hit.
[Graphical view ]
PROSITEi PS01238. GDA1_CD39_NTPASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Sequence, annotation, and analysis of synteny between rice chromosome 3 and diverged grass species."
    The rice chromosome 3 sequencing consortium
    Buell C.R., Yuan Q., Ouyang S., Liu J., Zhu W., Wang A., Maiti R., Haas B., Wortman J., Pertea M., Jones K.M., Kim M., Overton L., Tsitrin T., Fadrosh D., Bera J., Weaver B., Jin S.
    , Johri S., Reardon M., Webb K., Hill J., Moffat K., Tallon L., Van Aken S., Lewis M., Utterback T., Feldblyum T., Zismann V., Iobst S., Hsiao J., de Vazeille A.R., Salzberg S.L., White O., Fraser C.M., Yu Y., Kim H., Rambo T., Currie J., Collura K., Kernodle-Thompson S., Wei F., Kudrna K., Ammiraju J.S.S., Luo M., Goicoechea J.L., Wing R.A., Henry D., Oates R., Palmer M., Pries G., Saski C., Simmons J., Soderlund C., Nelson W., de la Bastide M., Spiegel L., Nascimento L., Huang E., Preston R., Zutavern T., Palmer L., O'Shaughnessy A., Dike S., McCombie W.R., Minx P., Cordum H., Wilson R., Jin W., Lee H.R., Jiang J., Jackson S.
    Genome Res. 15:1284-1291(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Nipponbare.

Entry informationi

Entry nameiAPY1_ORYSJ
AccessioniPrimary (citable) accession number: Q8H7L6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 31, 2012
Last sequence update: March 1, 2003
Last modified: October 29, 2014
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3