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Q8H7L6 (APY1_ORYSJ) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 53. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable apyrase 1

Short name=OsAPY1
EC=3.6.1.5
Alternative name(s):
ATP-diphosphatase
ATP-diphosphohydrolase
Adenosine diphosphatase
Short name=ADPase
Gene names
Name:APY1
Ordered Locus Names:Os03g0328400, LOC_Os03g21120
ORF Names:OSJNBb0014I10.10
OrganismOryza sativa subsp. japonica (Rice) [Reference proteome]
Taxonomic identifier39947 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza

Protein attributes

Sequence length489 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the hydrolysis of phosphoanhydride bonds of nucleoside tri- and di-phosphates By similarity.

Catalytic activity

A nucleoside 5'-triphosphate + 2 H2O = a nucleoside 5'-phosphate + 2 phosphate.

Cofactor

Calcium By similarity.

Subcellular location

Membrane; Single-pass type II membrane protein By similarity.

Sequence similarities

Belongs to the GDA1/CD39 NTPase family.

Ontologies

Keywords
   Cellular componentMembrane
   DomainSignal-anchor
Transmembrane
Transmembrane helix
   LigandATP-binding
Calcium
Nucleotide-binding
   Molecular functionHydrolase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentintegral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

hydrolase activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 489489Probable apyrase 1
PRO_0000419907

Regions

Topological domain1 – 2828Cytoplasmic Potential
Transmembrane29 – 4921Helical; Signal-anchor for type II membrane protein; Potential
Topological domain50 – 489440Extracellular Potential
Nucleotide binding89 – 9911ATP-binding Probable
Nucleotide binding235 – 24511ATP-binding Probable
Compositional bias12 – 165Poly-Gln
Compositional bias368 – 3736Poly-Gly

Sites

Active site2111Proton acceptor By similarity

Sequences

Sequence LengthMass (Da)Tools
Q8H7L6 [UniParc].

Last modified March 1, 2003. Version 1.
Checksum: 0BF6BF154488D38E

FASTA48952,799
        10         20         30         40         50         60 
MRRFSAAAGA RQQQQQGEAV SDRVLRFRGV LVVVLAPVLL ISLVLLLMPR APASATVEGS 

        70         80         90        100        110        120 
AGELVAAAGR RWGPRAVSGL GDGSTRYAVI FDAGSSGSRV HVYCFDGNLD LLPIGKEIEL 

       130        140        150        160        170        180 
FKQKKPGLSA YAMDPQEAAK SLVSLLEEAE KVIPVELREQ TPVRVGATAG LRALGTEKSE 

       190        200        210        220        230        240 
EILQAVRDLL QDKSSFRSQP EWVTVLDGSQ EGAFQWVTIN YLLGNLGKPY SHTVGVVDLG 

       250        260        270        280        290        300 
GGSVQMAYAI SEKDAGKAPP VAEGEDSYVK ELLLKGTTYY LYVHSYLRYG LLAARAEILK 

       310        320        330        340        350        360 
AGEGNDYRNC MLEGHHGQYR YGDDIFEASG LSSGASYSKC RAVAVRALKV DEPACTHMKC 

       370        380        390        400        410        420 
TFGGVWNGGG GDGQKNLFVA SFFFDRAAEA GFVNPKAPFA KVKPSDFEEA ARRVCKLNVK 

       430        440        450        460        470        480 
DAQATYPDVS EENVPYLCMD LVYQYTLLVD GFGVDPYQDI TLVKKVPYSN SFVEAAWPLG 


SAIEVASSS 

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AC126222 Genomic DNA. Translation: AAN65004.1.
DP000009 Genomic DNA. Translation: ABF95735.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Organism-specific databases

GrameneQ8H7L6.

Phylogenomic databases

OMASYSKCRA.

Family and domain databases

InterProIPR000407. GDA1_CD39_NTPase.
[Graphical view]
PANTHERPTHR11782. PTHR11782. 1 hit.
PfamPF01150. GDA1_CD39. 1 hit.
[Graphical view]
PROSITEPS01238. GDA1_CD39_NTPASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameAPY1_ORYSJ
AccessionPrimary (citable) accession number: Q8H7L6
Entry history
Integrated into UniProtKB/Swiss-Prot: October 31, 2012
Last sequence update: March 1, 2003
Last modified: May 14, 2014
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Oryza sativa (rice)

Index of Oryza sativa entries and their corresponding gene designations