Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q8H7F6 (GRS16_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 78. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Monothiol glutaredoxin-S16, chloroplastic

Short name=AtGrxS16
Alternative name(s):
CAXIP1-like protein
Gene names
Name:GRXS16
Ordered Locus Names:At2g38270
ORF Names:F16M14.20
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis

Protein attributes

Sequence length293 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

May only reduce GSH-thiol disulfides, but not protein disulfides Potential.

Subcellular location

Plastidchloroplast Potential.

Sequence similarities

Belongs to the glutaredoxin family. CGFS subfamily.

Contains 1 glutaredoxin domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Transit peptide1 – 6262Chloroplast Potential
Chain63 – 293231Monothiol glutaredoxin-S16, chloroplastic
PRO_0000268736

Regions

Domain194 – 293100Glutaredoxin
Region276 – 2772Glutathione binding By similarity

Sites

Metal binding2191Iron-sulfur (2Fe-2S); shared with dimeric partner By similarity
Binding site2111Glutathione By similarity
Binding site2511Glutathione By similarity
Binding site2631Glutathione; via amide nitrogen and carbonyl oxygen By similarity

Experimental info

Sequence conflict1941E → G in AAN60257. Ref.2

Secondary structure

....................... 293
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
Q8H7F6 [UniParc].

Last modified December 12, 2006. Version 2.
Checksum: 6B2E6337F8C5F050

FASTA29332,206
        10         20         30         40         50         60 
MAAITISSSL HASASPRVVR PHVSRNTPVI TLYSRFTPSF SFPSLSFTLR DTAPSRRRSF 

        70         80         90        100        110        120 
FIASAVKSLT ETELLPITEA DSIPSASGVY AVYDKSDELQ FVGISRNIAA SVSAHLKSVP 

       130        140        150        160        170        180 
ELCGSVKVGI VEEPDKAVLT QAWKLWIEEH IKVTGKVPPG NKSGNNTFVK QTPRKKSDIR 

       190        200        210        220        230        240 
LTPGRHVELT VPLEELIDRL VKESKVVAFI KGSRSAPQCG FSQRVVGILE SQGVDYETVD 

       250        260        270        280        290 
VLDDEYNHGL RETLKNYSNW PTFPQIFVKG ELVGGCDILT SMYENGELAN ILN 

« Hide

References

« Hide 'large scale' references
[1]"Cloning and characterization of CXIP1 A novel PICOT domain-containing Arabidopsis protein that associates with CAX1."
Cheng N.-H., Hirschi K.D.
J. Biol. Chem. 278:6503-6509(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[2]"Signal peptide selection derived cDNAs from Arabidopsis thaliana leaves and guard cells."
Stracke R., Palme K.
Submitted (AUG-1998) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
[3]"Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana."
Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D., Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V., Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S., Cronin L.A. expand/collapse author list , Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J., Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M., Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O., Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.
Nature 402:761-768(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[4]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[5]"Functional annotation of a full-length Arabidopsis cDNA collection."
Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T., Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y., Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K., Shinagawa A., Shinozaki K.
Science 296:141-145(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.
[6]"Empirical analysis of transcriptional activity in the Arabidopsis genome."
Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G. expand/collapse author list , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.
[7]"Full-length cDNA from Arabidopsis thaliana."
Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B., Feldmann K.A.
Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
[8]"Plant glutaredoxins: still mysterious reducing systems."
Rouhier N., Gelhaye E., Jacquot J.-P.
Cell. Mol. Life Sci. 61:1266-1277(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: GENE FAMILY, NOMENCLATURE.
[9]"Genome-wide analysis of plant glutaredoxin systems."
Rouhier N., Couturier J., Jacquot J.-P.
J. Exp. Bot. 57:1685-1696(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: GENE FAMILY.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AY157989 mRNA. Translation: AAO19648.1.
AF083698 mRNA. Translation: AAN60257.1.
AC003028 Genomic DNA. Translation: AAC27175.1.
CP002685 Genomic DNA. Translation: AEC09515.1.
AK117441 mRNA. Translation: BAC42106.1.
BT004974 mRNA. Translation: AAO50507.1.
AY086273 mRNA. Translation: AAM64346.1.
PIRT01258.
RefSeqNP_565885.1. NM_129383.2.
UniGeneAt.25559.
At.71438.

3D structure databases

PDBe
RCSB-PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
2LWFNMR-A63-170[»]
ProteinModelPortalQ8H7F6.
SMRQ8H7F6. Positions 62-172, 195-292.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid3749. 12 interactions.
IntActQ8H7F6. 7 interactions.
STRING3702.AT2G38270.1-P.

Proteomic databases

PaxDbQ8H7F6.
PRIDEQ8H7F6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT2G38270.1; AT2G38270.1; AT2G38270.
GeneID818407.
KEGGath:AT2G38270.

Organism-specific databases

TAIRAT2G38270.

Phylogenomic databases

eggNOGCOG0278.
HOGENOMHOG000243994.
InParanoidQ8H7F6.
OMAYNYGLRE.
PhylomeDBQ8H7F6.

Gene expression databases

GenevestigatorQ8H7F6.

Family and domain databases

Gene3D3.40.30.10. 1 hit.
InterProIPR002109. Glutaredoxin.
IPR004480. Monothiol_GRX-rel.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PANTHERPTHR10293. PTHR10293. 1 hit.
PfamPF00462. Glutaredoxin. 1 hit.
[Graphical view]
SUPFAMSSF52833. SSF52833. 1 hit.
TIGRFAMsTIGR00365. TIGR00365. 1 hit.
PROSITEPS51354. GLUTAREDOXIN_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameGRS16_ARATH
AccessionPrimary (citable) accession number: Q8H7F6
Secondary accession number(s): O80451, Q8LD13
Entry history
Integrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: December 12, 2006
Last modified: May 14, 2014
This is version 78 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names