Q8H4S6 (P2C64_ORYSJ) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable protein phosphatase 2C 64
Short name=OsPP2C64
EC=3.1.3.16

Gene names

Ordered Locus Names:	Os07g0566200, LOC_Os07g37890
ORF Names:	OJ1773_H01.121, OsJ_023811

Organism

Oryza sativa subsp. japonica (Rice) [Reference proteome]

Taxonomic identifier

39947 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Magnoliophyta › Liliopsida › commelinids › Poales › Poaceae › BEP clade › Ehrhartoideae › Oryzeae › Oryza › Oryza sativa

Protein attributes

Sequence length	427 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Catalytic activity	A phosphoprotein + H2O = a protein + phosphate.
Cofactor	Binds 2 magnesium or manganese ions per subunit By similarity.
Sequence similarities	Belongs to the PP2C family. Contains 1 PP2C-like domain.

Ontologies

Keywords
Ligand	Magnesium Manganese Metal-binding
Molecular function	Hydrolase Protein phosphatase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	metabolic process Inferred from electronic annotation. Source: GOC
Cellular_component	plasma membrane Inferred from electronic annotation. Source: EnsemblPlants/Gramene
Molecular_function	metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW phosphoprotein phosphatase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 427	427	Probable protein phosphatase 2C 64		PRO_0000363311
Regions
	Domain	52 – 317	266	PP2C-like
	Compositional bias	24 – 28	5	Poly-Arg
Sites
	Metal binding	89	1	Manganese 1 By similarity
	Metal binding	89	1	Manganese 2 By similarity
	Metal binding	90	1	Manganese 1; via carbonyl oxygen By similarity
	Metal binding	276	1	Manganese 2 By similarity
	Metal binding	322	1	Manganese 2 By similarity
Experimental info
	Sequence conflict	64	1	G → E in AK069418. Ref.4

Sequences

	Sequence		Length	Mass (Da)
	Q8H4S6 [UniParc]. Last modified October 1, 2003. Version 2. Checksum: CD4E6B454691CA2B	FASTA	427	46,299
	10 20 30 40 50 60 MGNCVARSGT AVDAGGDGGE DGKRRRRRWK APREDQLGMV PGRIFSNDGR SRTATVYTQQ 70 80 90 100 110 120 GRKGINQDAM LVWDGFGGED DGVLCGVFDG HGPHGHVVAR RVRDSLPLRL MSAARDSGAD 130 140 150 160 170 180 MPAAAWRKAF ARAYKAMDKD LRSHPSLDCF CSGSTAVTVL KLGSDLYMAN IGDSRAVLGS 190 200 210 220 230 240 REATGGGMVA VQLTVDLKPD VPSEAERIKK CRGRVFALQD EPEVPRVWLP FDDAPGLAMA 250 260 270 280 290 300 RAFGDFCLKD YGVISVPEFF HWSLTEKDQF VILASDGVWD VLSNQEAVDI VSASPSRSKA 310 320 330 340 350 360 AKSLVEAATR EWKTKYPTSK IDDCAVVCLY LDGKMDHERD STASLDNISI EEGSVADPNE 370 380 390 400 410 420 PQEQEPTLTR NFTVRTVAGS TQEKTLAGVD ARIAGVANDQ NWSGLDGVTR VNSLVQLPRF SEERAIG

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The map-based sequence of the rice genome." International rice genome sequencing project (IRGSP) Nature 436:793-800(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.
[2]	"The rice annotation project database (RAP-DB): 2008 update." The rice annotation project (RAP) Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed] [Europe PMC] [Abstract] Cited for: GENOME REANNOTATION. Strain: cv. Nipponbare.
[3]	"The genomes of Oryza sativa: a history of duplications." Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S., Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L. , Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J., Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X., Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y., Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L., Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H., Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z., Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L., Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F., Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q., Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J., Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M., McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H. PLoS Biol. 3:266-281(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.
[4]	"Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice." The rice full-length cDNA consortium Science 301:376-379(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: cv. Nipponbare.
[5]	"Genome-wide and expression analysis of protein phosphatase 2C in rice and Arabidopsis." Xue T., Wang D., Zhang S., Ehlting J., Ni F., Jacab S., Zheng C., Zhong Y. BMC Genomics 9:550-550(2008) [PubMed] [Europe PMC] [Abstract] Cited for: GENE FAMILY, NOMENCLATURE.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP003932 Genomic DNA. Translation: BAC79670.1. AP008213 Genomic DNA. Translation: BAF21930.1. CM000144 Genomic DNA. Translation: EAZ40328.1. AK069418 mRNA. No translation available.
RefSeq	NP_001060016.1. NM_001066551.1.
UniGene	Os.11587.
3D structure databases
ProteinModelPortal	Q8H4S6.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblPlants	LOC_Os07g37890.1; LOC_Os07g37890.1; LOC_Os07g37890.
GeneID	4343629.
KEGG	osa:4343629.
Organism-specific databases
Gramene	Q8H4S6.
Phylogenomic databases
eggNOG	COG0631.
HOGENOM	HOG000233897.
OMA	DHERDST.
ProtClustDB	CLSN2696854.
Gene expression databases
ArrayExpress	Q8H4S6.
Family and domain databases
Gene3D	3.60.40.10. 1 hit.
InterPro	IPR001932. PP2C-like. IPR015655. Protein_Pase_2C. [Graphical view]
PANTHER	PTHR13832. PTHR13832. 1 hit.
Pfam	PF00481. PP2C. 1 hit. [Graphical view]
SMART	SM00331. PP2C_SIG. 1 hit. SM00332. PP2Cc. 1 hit. [Graphical view]
SUPFAM	SSF81606. PP2C-related. 1 hit.
PROSITE	PS01032. PP2C. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

P2C64_ORYSJ

Accession

Primary (citable) accession number: Q8H4S6

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 10, 2009
Last sequence update:	October 1, 2003
Last modified:	April 3, 2013
This is version 59 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program