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Q8H1G6 (PTI11_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 97. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Web links·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
PTI1-like tyrosine-protein kinase 1

Short name=PTI1-1
EC=2.7.10.2
Gene names
Name:PTI11
Ordered Locus Names:At1g06700
ORF Names:F12K11.1, F4H5.21
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis

Protein attributes

Sequence length361 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.

Subunit structure

Interacts with OXI1. Ref.5

Subcellular location

Cell membrane; Peripheral membrane protein Ref.6.

Post-translational modification

Autophosphorylated and phosphorylated by OXI1. Ref.5

Sequence similarities

Belongs to the protein kinase superfamily. Tyr protein kinase family.

Contains 1 protein kinase domain.

Sequence caution

The sequence AAF24808.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.

The sequence AAF63147.1 differs from that shown. Reason: Erroneous gene model prediction.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 361361PTI1-like tyrosine-protein kinase 1
PRO_0000403322

Regions

Domain68 – 350283Protein kinase
Nucleotide binding74 – 829ATP By similarity

Sites

Active site2001Proton acceptor By similarity
Binding site961ATP By similarity

Experimental info

Sequence conflict3431V → A in AAK44075. Ref.3

Sequences

Sequence LengthMass (Da)Tools
Q8H1G6 [UniParc].

Last modified March 1, 2003. Version 1.
Checksum: 49CD8A555DEF458B

FASTA36139,820
        10         20         30         40         50         60 
MRKWICCTCQ IEDSNEEQQL KSSQQQSDAN HKNSKPAPVA KHEVKKEALP IEVPPLSLDE 

        70         80         90        100        110        120 
VKEKTENFGS KALIGEGSYG RVYYATLNDG VAVALKKLDV APEAETDTEF LSQVSMVSRL 

       130        140        150        160        170        180 
KHENLIQLLG FCVDGNLRVL AYEFATMGSL HDILHGRKGV QGAQPGPTLD WITRVKIAVE 

       190        200        210        220        230        240 
AARGLEYLHE KSQPPVIHRD IRSSNVLLFE DYKAKIADFN LSNQAPDNAA RLHSTRVLGT 

       250        260        270        280        290        300 
FGYHAPEYAM TGQLTQKSDV YSFGVVLLEL LTGRKPVDHT MPRGQQSLVT WATPRLSEDK 

       310        320        330        340        350        360 
VKQCIDPKLK ADYPPKAVAK LAAVAALCVQ YEAEFRPNMS IVVKALQPLL KPPAAAPAPE 


S 

« Hide

References

« Hide 'large scale' references
[1]"Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana."
Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K. expand/collapse author list , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W.
Nature 408:816-820(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[2]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[3]"Empirical analysis of transcriptional activity in the Arabidopsis genome."
Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G. expand/collapse author list , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.
[4]"Analysis of multiple occurrences of alternative splicing events in Arabidopsis thaliana using novel sequenced full-length cDNAs."
Iida K., Fukami-Kobayashi K., Toyoda A., Sakaki Y., Kobayashi M., Seki M., Shinozaki K.
DNA Res. 16:155-164(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.
Tissue: Root.
[5]"The Arabidopsis protein kinase PTI1-2 is activated by convergent phosphatidic acid and oxidative stress signaling pathways downstream of PDK1 and OXI1."
Anthony R.G., Khan S., Costa J., Pais M.S., Boegre L.
J. Biol. Chem. 281:37536-37546(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: INTERACTION WITH OXI1, AUTOPHOSPHORYLATION, PHOSPHORYLATION BY OXI1.
[6]"A high content in lipid-modified peripheral proteins and integral receptor kinases features in the arabidopsis plasma membrane proteome."
Marmagne A., Ferro M., Meinnel T., Bruley C., Kuhn L., Garin J., Barbier-Brygoo H., Ephritikhine G.
Mol. Cell. Proteomics 6:1980-1996(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AC007592 Genomic DNA. Translation: AAF24808.1. Different initiation.
AC011001 Genomic DNA. Translation: AAF63147.1. Sequence problems.
CP002684 Genomic DNA. Translation: AEE28025.1.
CP002684 Genomic DNA. Translation: AEE28026.1.
AF370260 mRNA. Translation: AAK44075.1.
AY150374 mRNA. Translation: AAN12919.1.
AK317491 mRNA. Translation: BAH20156.1.
PIRF86201.
RefSeqNP_001030981.1. NM_001035904.1.
NP_172155.1. NM_100547.2.
UniGeneAt.12093.

3D structure databases

ProteinModelPortalQ8H1G6.
SMRQ8H1G6. Positions 15-347.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid22421. 2 interactions.
IntActQ8H1G6. 1 interaction.
MINTMINT-8085735.

Proteomic databases

PaxDbQ8H1G6.
PRIDEQ8H1G6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT1G06700.1; AT1G06700.1; AT1G06700.
AT1G06700.2; AT1G06700.2; AT1G06700.
GeneID837180.
KEGGath:AT1G06700.

Organism-specific databases

GeneFarm1782. 139.
TAIRAT1G06700.

Phylogenomic databases

eggNOGCOG0515.
HOGENOMHOG000116550.
InParanoidQ8H1G6.
OMATENFGSK.
PhylomeDBQ8H1G6.
ProtClustDBCLSN2682494.

Enzyme and pathway databases

BioCycARA:AT1G06700-MONOMER.
ARA:GQT-2033-MONOMER.

Gene expression databases

GenevestigatorQ8H1G6.

Family and domain databases

InterProIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR001245. Ser-Thr/Tyr_kinase_cat_dom.
IPR008266. Tyr_kinase_AS.
[Graphical view]
PfamPF07714. Pkinase_Tyr. 1 hit.
[Graphical view]
SUPFAMSSF56112. SSF56112. 1 hit.
PROSITEPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00109. PROTEIN_KINASE_TYR. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePTI11_ARATH
AccessionPrimary (citable) accession number: Q8H1G6
Secondary accession number(s): Q94K67, Q9M9X8, Q9SHK8
Entry history
Integrated into UniProtKB/Swiss-Prot: January 11, 2011
Last sequence update: March 1, 2003
Last modified: April 16, 2014
This is version 97 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names